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3D-printed devices for continuous-flow organic chemistry
Open accessAbstract
We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds. Robust and inexpensive 3D-printed reactionware devices are easily connected using standard fittings resulting in complex, custom-made flow systems, including multiple reactors in a series with in-line, real-time analysis using an ATR-IR flow cell. As a proof of concept, we utilized two types of organic reactions, imine syntheses and imine reductions, to show how different reactor configurations and substrates give different products.
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Cited by
Evaluation of 3D Printing and Its Potential Impact on Biotechnology and the Chemical Sciences
Gross, B. C., Erkal, J. L., Lockwood, S. Y., Chen, C., & Spence, D. M. (2014) · Analytical Chemistry · doi:10.1021/ac403397r · Cited by 1,746
3D-printing technologies for electrochemical applications
Ambrosi, A., & Pumera, M. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00714c · Cited by 1,040
González-Henríquez, C. M., Sarabia-Vallejos, M. A., & Rodriguez-Hernandez, J. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2019.03.001 · Cited by 562
3D Printable Graphene Composite
Wei, X., Li, D., Jiang, W., Gu, Z., Wang, X., Zhang, Z., & Sun, Z. (2015) · Scientific Reports · doi:10.1038/srep11181 · Cited by 481
Heterogeneous catalysis in continuous flow microreactors: A review of methods and applications
Tanimu, A., Jaenicke, S., & Alhooshani, K. (2017) · Chemical Engineering Journal · doi:10.1016/j.cej.2017.06.161 · Cited by 355
Metadata
- Authors
- Dragone, V., Sans, V., Rosnes, M. H., Kitson, P. J., & Cronin, L.
- Venue
- Beilstein Journal of Organic Chemistry
- Publisher
- Beilstein Institut
- Published
- 2013-05-16
- Volume
- 9
- Pages
- 951-959
- ISSN
- 1860-5397 (ISSN-L)
- OpenAlex
- W2164136492
- Cited by
- 174
- References
- 0
- FWCI
- 6.38
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Dragone, V., Sans, V., Rosnes, M. H., Kitson, P. J., & Cronin, L. (2013). 3D-printed devices for continuous-flow organic chemistry. Beilstein Journal of Organic Chemistry. https://doi.org/10.3762/bjoc.9.109
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