The DOI matches its Crossref record.
Efficacy and safety of SPN-812 (extended-release viloxazine) in children and adolescents with attention-deficit/hyperactivity disorder: a systematic review and meta-analysis
Open accessAbstract
eview question / Objective P:children and adolescents with ADHD; I:SPN-812; C:placebo; O:ADHD-RS-5, Conners 3-PS, WFIRS-P, CGI-I score,AEs and SAEs; S:RCTs.Condition being studied ADHD (attention deficit hyperactivity disorder) is a widespread and debilitating neuropsychiatric condition that affects children and teenagers.METHODS Participant or population Children and adolescents (6-17 years old) who were diagnosed with ADHD.Intervention Different doses of SPN-812 vs. placebo.Comparator ADHD-RS-5, Conners 3-PS, WFIRS-P, CGI-I score,AEs and SAEs.Study designs to be included Randomized controlled trials.Eligibility criteria Inclusion criteria :(1) The type of study must be an RCT; (2) language: English(3) Subjects: diagnosed ADHD patients (6-17 years old); (4) intervention: different doses of SPN-812 and placebo; (5) Indicators: ADHD-RS-5, Conners 3-PS, WFIRS-P, CGI-I score, AEs and SAEs.Case reports, case reviews, retrospective studies, and cohort studies and studies with active controls were excluded.
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ADHD in Adulthood: Clinical Presentation, Comorbidities, and Treatment Perspectives
Bogdańska-Chomczyk, E., Majewski, M. K., & Kozłowska, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262211020 · Cited by 15
(2025) · Wiley eBooks · doi:10.1002/9781118941430.refs
Metadata
- Authors
- Tan, X., Xu, Y., Wang, S., Li, J., Hu, C., Chen, Z., Cheng, Q., & Wang, Z.
- Affiliations
- First Affiliated Hospital of Soochow University (CN)
- Publisher
- INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols
- Published
- 2023-09-16
- OpenAlex
- W4386797299
- Cited by
- 2
- References
- 0
- Citations by year
- 2025: 2
- Type
- report
- Language
- en
- Open access
- gold
- doi.org
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmaceutical studies and practices
- Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
- Keywords
- attention deficit hyperactivity disorder, children and adolescents, stimulant-free treatment, ADHD symptom severity, adverse events, treatment efficacy and safety
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