The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
Knee osteoarthritis: Current status and research progress in treatment (Review)
Open accessAbstract
Knee osteoarthritis (KOA) is a common chronic articular disease worldwide. It is also the most common form of OA and is characterized by high morbidity and disability rates. With the gradual increase in life expectancy and ageing population, KOA not only affects the quality of life of patients, but also poses a burden on global public health. OA is a disease of unknown etiology and complex pathogenesis. It commonly affects joints subjected to greater loads and higher levels of activity. The knee joint, which is the most complex joint of the human body and bears the greatest load among all joints, is therefore most susceptible to development of OA. KOA lesions may involve articular cartilage, synovium, joint capsule and periarticular muscles, causing irreversible articular damage. Factors such as mechanical overload, inflammation, metabolism, hormonal changes and ageing serve key roles in the acceleration of KOA progression. The clinical diagnosis of KOA is primarily based on combined analysis of symptoms, signs, imaging and laboratory examination results. At present, there is no cure for KOA and the currently available therapies primarily focus on symptomatic treatment and delay of disease progression. Knee replacement surgery is typically performed in patients with advanced disease. The current study presents a review of epidemiological characteristics, risk factors, histopathological manifestations, pathogenesis, diagnosis, treatment modalities and progress in KOA research.
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Cites
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Cited by
Puts, S., Njemini, R., Bilterys, T., Lefeber, N., Scheerlinck, T., Nijs, J., Beckwée, D., & Bautmans, I. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13175212 · Cited by 15
Metadata
- Authors
- Geng, R., Li, J., Yu, C., Zhang, C., Chen, F., Chen, J., Ni, H., Wang, J., Kang, K., Wei, Z., Xu, Y., & Jin, T.
- Venue
- Experimental and Therapeutic Medicine
- Publisher
- Spandidos Publications
- Published
- 2023-08-25
- Volume
- 26
- Issue
- 4
- Pages
- 481-481
- ISSN
- 1792-0981 (ISSN-L)
- 1792-1015
- OpenAlex
- W4386168264
- Cited by
- 266
- References
- 135
- FWCI
- 46.05
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Geng, R., Li, J., Yu, C., Zhang, C., Chen, F., Chen, J., Ni, H., Wang, J., Kang, K., Wei, Z., Xu, Y., & Jin, T. (2023). Knee osteoarthritis: Current status and research progress in treatment (Review). Experimental and Therapeutic Medicine. https://doi.org/10.3892/etm.2023.12180
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
