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RAPID3 (Routine Assessment of Patient Index Data 3), a Rheumatoid Arthritis Index Without Formal Joint Counts for Routine Care: Proposed Severity Categories Compared to Disease Activity Score and Clinical Disease Activity Index Categories
Open accessAbstract
Objective: To compare 4 categories (high, moderate, and low severity, and near-remission) of RAPID3 (Routine Assessment of Patient Index Data 3), an index without formal joint counts, which is scored in < 10 seconds to 4 categories of the DiseaseActivity Score (DAS28) and Clinical Disease Activity Index (CDAI) in patients with rheumatoid arthritis (RA). Methods: All patients complete a Multidimensional Health Assessment Questionnaire (MDHAQ) at each visit. A physician/assessor 28-joint count and erythrocyte sedimentation rate (ESR) were completed in 285 patients with RA in usual care by 3 rheumatologists to score DAS28, CDAI, and RAPID3. RAPID3 includes the 3 MDHAQ patient self-report RA Core Data Set measures for physical function, pain, and patient global estimate. Proposed RAPID3 (range 0–10) severity categories of high (> 4), moderate (2.01–4), low (1.01–2), and near-remission (≤ 1) were compared to DAS (0–10) activity categories of high (> 5.1), moderate (3.21–5.1), low (2.61–3.2), and remission (≤ 2.6), and CDAI (0–76) categories of > 22, 10.1–22.0, 2.9–10.0, and ≤ 2.8. Additional RAPID scores, which add to RAPID3 a physician/assessor or patient self-report joint count and/or assessor global estimate, were also analyzed. Statistical significance was analyzed using Spearman correlations, cross-tabulations, and kappa statistics. Results: All RAPID scores were correlated significantly with DAS28 and CDAI (rho > 0.65, p < 0.001). Overall, 78%–84% of patients who met DAS28 or CDAI moderate/high activity criteria met similar RAPID severity criteria, and 68%–77% who met DAS28 or CDAI remission/low activity criteria also met similar RAPID criteria. RAPID3 was as informative as other indices. Conclusion: RAPID3 provides a feasible, informative quantitative index for busy clinical settings.
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Pincus, T., Strand, V., Koch, G., Amara, I., Crawford, B., Wolfe, F., Cohen, S., & Felson, D. (2003) · Arthritis & Rheumatism · doi:10.1002/art.10824 · Cited by 146
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Smolen, J. S., Aletaha, D., & McInnes, I. B. (2016) · The Lancet · doi:10.1016/s0140-6736(16)30173-8 · Cited by 4,870
The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties
Bennett, R. M., Friend, R., Jones, K. D., Ward, R., Han, B. K., & Ross, R. L. (2009) · Arthritis Research & Therapy · doi:10.1186/ar2783 · Cited by 814
Anderson, J., Caplan, L., Yazdany, J., Robbins, M. L., Neogi, T., Michaud, K., Saag, K. G., O'dell, J. R., & Kazi, S. (2012) · Arthritis Care & Research · doi:10.1002/acr.21649 · Cited by 748
Anderson, J. K., Zimmerman, L., Caplan, L., & Michaud, K. (2011) · Arthritis Care & Research · doi:10.1002/acr.20621 · Cited by 260
Pincus, T., Yazici, Y., & Bergman, M. J. (2009) · Rheumatic Disease Clinics of North America · doi:10.1016/j.rdc.2009.10.008 · Cited by 163
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Metadata
- Authors
- PINCUS, T., SWEARINGEN, C. J., BERGMAN, M., & YAZICI, Y.
- Venue
- The Journal of Rheumatology
- Publisher
- The Journal of Rheumatology
- Published
- 2008-11
- Volume
- 35
- Issue
- 11
- Pages
- 2136-2147
- ISSN
- 0315-162X (ISSN-L)
- 1499-2752
- OpenAlex
- W2100039847
- Cited by
- 349
- References
- 1
- FWCI
- 11.30
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: RAPID3 (Routine Assessment of Patient Index Data 3), a Rheumatoid Arthritis Index Without Formal Joint Counts for Routine Care: Proposed Severity Categories Compared to Disease Activity Score and Clinical Disease Activity Index Categories. https://app.cochat.ai/papers/10.3899/jrheum.080182
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- PINCUS, T., SWEARINGEN, C. J., BERGMAN, M., & YAZICI, Y. (2008). RAPID3 (Routine Assessment of Patient Index Data 3), a Rheumatoid Arthritis Index Without Formal Joint Counts for Routine Care: Proposed Severity Categories Compared to Disease Activity Score and Clinical Disease Activity Index Categories. The Journal of Rheumatology. https://doi.org/10.3899/jrheum.080182
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