Minimal change nephrotic syndrome showing complete remission after resection of a neurofibroma in a type I neurofibromatosis patient
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Twelve cases of NF1 associated with glomerular disease have been reported.
“To the best of our knowledge, 12 cases of NF1 associated with glomerular disease have been reported (membranous glomerulopathy, 4 cases; focal segmental glomerulosclerosis (FSGS), 3 cases; IgA nephropathy, 2 cases; minimal-change nephrotic syndrome, 2 cases; and idiopathic nephrotic syndrome, 1 case) [12,13]”
From A case of lipoprotein glomerulopathy with a rare apolipoprotein E isoform combined with neurofibromatosis type I (2018) · cites this paper as [13]
In the paper’s main text (page unavailable), the authors say that only a few cases of nephrotic syndrome in NF1 had been reported and describe their own NF1 case with minimal-change disease. The paper does not state that 12 cases of NF1-associated glomerular disease had been reported or give the cited breakdown by diagnosis. (LLM, conf=0.85)
Experimental — accuracy not yet measuredNF1 is associated with glomerular diseases.
“These findings suggest the association of NF1 with glomerular diseases.”
From A case of lipoprotein glomerulopathy with a rare apolipoprotein E isoform combined with neurofibromatosis type I (2018) · cites this paper as [13]
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Cites
The neurofibromatosis type 1 gene encodes a protein related to GAP
Xu, G., O'Connell, P., Viskochil, D., Cawthon, R., Robertson, M., Culver, M., Dunn, D., Stevens, J., Gesteland, R., White, R., et al. (1990) · Cell · doi:10.1016/0092-8674(90)90024-9 · Cited by 1,095 · see citing works
Flagged first, then by citations
Research works printed but not linked: 4
- [1]Khan GA Melman A Bank N Renal involvement in neurocutaneous syndromes J Am Soc Nephrol 1995 5 1411 1417 7703378
- [2]Glassock RJ Secondary minimal change disease Nephrol Dial Transplant 2003 18 Suppl 6 vi52 vi58 12953043
- [4]Godel M Hartleben B Herbach N Role of mTOR in podocyte function and diabetic nephropathy in humans and mice J Clin Invest 2011 121 2197 2209 21606591 PMC3104746
- [5]Hsueh YP Roberts AM Volta M Sheng M Roberts RG Bipartite interaction between neurofibromatosis type I protein (neurofibromin) and syndecan transmembrane heparan sulfate proteoglycans J Neurosci 2001 21 3764 3770 11356864 PMC6762697
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Takasaki, S., Matsunaga, A., Joh, K., & Saito, T. (2018) · CEN Case Reports · doi:10.1007/s13730-018-0309-2 · Cited by 7 · see citing works
- Authors
- Hyun, J. I., Min, J. W., Lee, H. M., Kim, Y. K., Choi, E. J., & Song, H. C.
- Affiliations
- Catholic University of Korea (KR)
- Corresponding author
- Song, Ho Cheol
- Venue
- The Korean Journal of Internal Medicine
- Published
- 2017-01-01
- Volume
- 32
- Issue
- 1
- Pages
- 186-189
- ISSN
- 1226-3303 (ISSN-L)
- 2005-6648
- PMC
- PMC5214715
- OpenAlex
- W2293951393
- Cited by
- 3
- References
- 1
- Citations by year
- 2025: 1 · 2019: 1 · 2018: 1
- FWCI
- 0.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- The Korean Journal of Internal Medicine (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Nephrology › Renal Diseases and Glomerulopathies
- Health Sciences › Medicine › Neurology › Neurofibromatosis and Schwannoma Cases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vasculitis and related conditions
- Keywords
- minimal change disease, nephrotic syndrome, neurofibroma, neurofibromatosis type 1, tumor resection, remission
- MeSH terms
- Adult, Biopsy, Female, Humans, Magnetic Resonance Imaging, Microscopy, Electron, Nephrosis, Lipoid, Neurofibromatosis 1, Remission Induction, Treatment Outcome, Neurofibroma, Plexiform
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