The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Zearalenone and its metabolites as endocrine disrupting chemicals
Open accessAbstract
Zearalenone (ZEA) is a macrocyclic β-resorcylic acid lactone produced by numerous species of Fusarium. It frequently contaminates corn and cereal products in many regions of the world. The biological activity of ZEA is dominated by its pronounced oestrogenicity, which is even enhanced in certain reductive metabolites. This review updates the metabolism in fungi, plants and mammalian systems, as well as the pharmacokinetics of ZEA. The present evidence for the hormonal effects of the parent mycoestrogen and some of its metabolites in vitro and in farm and experimental animals in vivo is reviewed, together with its association with endocrine-disruptive effects in humans. Possible mechanisms of the oestrogenic and carcinogenic activity of ZEA are discussed and future areas of research proposed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro
Takemura, H., Shim, J.-Y., Sayama, K., Tsubura, A., Zhu, B. T., & Shimoi, K. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2006.08.008 · Cited by 207
Cited by
Scientific Opinion on the risks for public health related to the presence of zearalenone in food
Chain, E. P. O. C. I. T. F. (2011) · EFSA Journal · doi:10.2903/j.efsa.2011.2197 · Cited by 490
Risks for animal health related to the presence of zearalenone and its modified forms in feed
(CONTAM), E. P. O. C. I. T. F. C., Knutsen, H., Alexander, J., Barregård, L., Bignami, M., Brüschweiler, B., Ceccatelli, S., Cottrill, B., Dinovi, M., Edler, L., et al. (2017) · EFSA Journal · doi:10.2903/j.efsa.2017.4851 · Cited by 292
Zearalenone as an endocrine disruptor in humans
Kowalska, K., Habrowska-Górczyńska, D. E., & Piastowska-Ciesielska, A. W. (2016) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2016.10.015 · Cited by 285
Metadata
- Authors
- Metzler, M., Pfeiffer, E., & Hildebrand, A.
- Venue
- World Mycotoxin Journal
- Publisher
- Walter de Gruyter GmbH
- Published
- 2010-11-01
- Volume
- 3
- Issue
- 4
- Pages
- 385-401
- ISSN
- 1875-0710 (ISSN-L)
- 1875-0796
- OpenAlex
- W2010188491
- Cited by
- 201
- References
- 1
- FWCI
- 9.46
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Zearalenone and its metabolites as endocrine disrupting chemicals. https://app.cochat.ai/papers/10.3920/wmj2010.1244
- The paper
- Metzler, M., Pfeiffer, E., & Hildebrand, A. (2010). Zearalenone and its metabolites as endocrine disrupting chemicals. World Mycotoxin Journal. https://doi.org/10.3920/wmj2010.1244
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
