The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Importance of methyl donors during reproduction
Open accessAbstract
There is growing evidence that optimal dietary intake of folate and choline (both involved in 1-carbon transfer or methylation) is important for successful completion of fetal development. Significant portions of the population are eating diets low in one, or both of these nutrients. Folates are important for normal neural tube closure in early gestation and the efficacy of diet fortification with folic acid in reducing incidence of neural tube defects is a major success story for public health nutrition. Similarly, maternal dietary choline is important for normal neural tube closure in the fetus and, later in gestation, also is important for neurogenesis in the fetal hippocampus with effects on memory that persist in adult offspring; higher choline intake being associated with enhanced memory performance. Though both folates and choline have many potentially independent mechanisms whereby they could influence fetal development, these two nutrients also have a common mechanism for action - altered methylation and related epigenetic effects on gene expression.
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Cites
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
van Praag, H., Kempermann, G., & Gage, F. H. (1999) · Nature Neuroscience · doi:10.1038/6368 · Cited by 3,880
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5293-5300.2003 · Cited by 2,019 · cited 1×
“Changes in dietary availability of methyl groups induces stable changes in gene methylation, altering gene expression and resulting phenotype (82, 83).”
BackgroundNeural tube defects and folate: case far from closed
Blom, H. J., Shaw, G. M., den Heijer, M., & Finnell, R. H. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1986 · Cited by 562
Niculescu, M. D., Craciunescu, C. N., & Zeisel, S. H. (2006) · The FASEB Journal · doi:10.1096/fj.05-4707com · Cited by 330
Self-citationDietary choline and betaine and the risk of distal colorectal adenoma in women
Cho, E., Willett, W. C., Colditz, G. A., Fuchs, C. S., Wu, K., Chan, A. T., Zeisel, S. H., & Giovannucci, E. L. (2007) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djm082 · Cited by 108
Cited by
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
Fardet, A. (2010) · Nutrition Research Reviews · doi:10.1017/s0954422410000041 · Cited by 1,030
Schmidt, R. J., Tancredi, D. J., Ozonoff, S., Hansen, R. L., Hartiala, J., Allayee, H., Schmidt, L. C., Tassone, F., & Hertz-Picciotto, I. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.004416 · Cited by 408
Early Life Nutrition, Epigenetics and Programming of Later Life Disease
Vickers, M. (2014) · Nutrients · doi:10.3390/nu6062165 · Cited by 366
Epigenetic influences on brain development and plasticity
Fagiolini, M., Jensen, C. L., & Champagne, F. A. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.05.009 · Cited by 362
Zimmermann, M. B. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26811c · Cited by 357
Metadata
- Authors
- Zeisel, S. H.
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2009-02
- Volume
- 89
- Issue
- 2
- Pages
- 673S-677S
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2096036780
- Cited by
- 240
- References
- 5
- FWCI
- 12.98
- Type
- journal article
- Language
- en
- Open access
- bronze
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