Cited by 587Antioxidant Activity and Oxidative StressRetinoids in leukemia and cellular processesNutrition, Health, and Society Studies

β-Carotene Is an Important Vitamin A Source for Humans

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Grune, Tilman, Lietz, Georg, Palou, Andreu, Ross, A. Catharine, Stahl, Wilhelm, Tang, Guangweng, Thurnham, David, Yin, Shi-an +1 more·2010·The Journal of Nutrition

Abstract

Experts in the field of carotenoids met at the Hohenheim consensus conference in July 2009 to elucidate the current status of β-carotene research and to summarize the current knowledge with respect to the chemical properties, physiological function, and intake of β-carotene. The experts discussed 17 questions and reached an agreement formulated in a consensus answer in each case. These consensus answers are based on published valid data, which were carefully reviewed by the individual experts and are justified here by background statements. Ascertaining the impact of β-carotene on the total dietary intake of vitamin A is complicated, because the efficiency of conversion of β-carotene to retinol is not a single ratio and different conversion factors have been used in various surveys and following governmental recommendations within different countries. However, a role of β-carotene in fulfilling the recommended intake for vitamin A is apparent from a variety of studies. Thus, besides elucidating the various functions, distribution, and uptake of β-carotene, the consensus conference placed special emphasis on the provitamin A function of β-carotene and the role of β-carotene in the realization of the required/recommended total vitamin A intake in both developed and developing countries. There was consensus that β-carotene is a safe source of vitamin A and that the provitamin A function of β-carotene contributes to vitamin A intake.

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References 149 · Cited by 587

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Authors
Grune, T., Lietz, G., Palou, A., Ross, A. C., Stahl, W., Tang, G., Thurnham, D., Yin, S.-A., & Biesalski, H. K.
Affiliations
  • University of Hohenheim (DE)
  • Newcastle University (GB)
  • Universitat de les Illes Balears (ES)
  • Pennsylvania State University (US)
  • Heinrich Heine University Düsseldorf (DE)
  • Tufts University (US)
  • University of Ulster (GB)
  • Chinese Center For Disease Control and Prevention (CN)
Corresponding author
Biesalski, Hans K.
Venue
The Journal of Nutrition
Publisher
Elsevier BV
Published
2010-12
Volume
140
Issue
12
Pages
2268S-2285S
ISSN
0022-3166 (ISSN-L)
OpenAlex
W2144548956
Cited by
587
References
149
Citations by year
2026: 39 · 2025: 60 · 2024: 62 · 2023: 49 · 2022: 66 · 2021: 61 · 2020: 54 · 2019: 32 · 2018: 28 · 2017: 25 · 2016: 29 · 2015: 18 · 2014: 14 · 2013: 19 · 2012: 22
FWCI
10.15
Type
journal article
Language
en
Open access
Locations
  • Journal of Nutrition (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Cancer Institute (R01CA090214)
  • National Institute of Diabetes and Digestive and Kidney Diseases (R01DK041479)
Topics
  • Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinoids in leukemia and cellular processes
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Nutrition, Health, and Society Studies
Keywords
beta-carotene, vitamin A, provitamin A, dietary intake, carotenoids, vitamin A deficiency, recommended intake, developing countries
MeSH terms
Humans, Vitamin A, beta Carotene

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