Enantioselective Addition of Dialkylzincs to Pyridinecarbaldehyde in the Presence of Chiral Aminoalcohols: Asymmetric Synthesis of Pyridylalkyl Alcohols

1-(3-Pyridyl) ethanol and -propanol were synthesized in moderate to good enantiomeric excesses by the enantioselective addition of dialkylzincs to nicotinaldehyde using N,N-dibutylnorephedrine as chiral catalyst