The DOI matches its Crossref record.
Granulocyte Chemotaxis: An Improved in Vitro Assay Employing 51Cr-Labeled Granulocytes
Abstract
A radioassay of granulocyte chemotaxis employing chromium-51 labeled cells and a double micropore filter system is presented. In comparison to the conventional Boyden chamber technique, this method offers significant advantages including: a) elimination of tedious filter staining and microscope counting resulting in a considerable saving in laboratory time, b) elimination of observer subjectivity, c) excellent sensitivity over a wide range of cell responses with no increase in variability, d) ability to monitor cellular events in all compartments of the chemotaxis chamber and e) a means for standardization of neutrophil chemotaxis among different laboratories.
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Citations
Cited by
Malech, H., Root, R., & Gallin, J. (1977) · The Journal of Cell Biology · doi:10.1083/jcb.75.3.666 · Cited by 279
Self-citationChemotactic activity in inflammatory bowel disease: Role of leukotriene B4
Lobos, E. A., Sharon, P., & Stenson, W. F. (1987) · Digestive Diseases and Sciences · doi:10.1007/bf01296664 · Cited by 143
Metadata
- Authors
- Gallin, J. I., Clark, R. A., & Kimball, H. R.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1973-01-01
- Volume
- 110
- Issue
- 1
- Pages
- 233-240
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1631426208
- Cited by
- 323
- References
- 0
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Granulocyte Chemotaxis: An Improved in Vitro Assay Employing 51Cr-Labeled Granulocytes. https://app.cochat.ai/papers/10.4049/jimmunol.110.1.233
- The paper
- Gallin, J. I., Clark, R. A., & Kimball, H. R. (1973). Granulocyte Chemotaxis: An Improved in Vitro Assay Employing 51Cr-Labeled Granulocytes. The Journal of Immunology. https://doi.org/10.4049/jimmunol.110.1.233
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
