Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal β-Catenin Pathway Function in an Alzheimer’s Disease Model

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Items 401–472 of 472

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11. Inflammation and the Pathophysiology of Astrocytes in Neurodegenerative Diseases
    Gordon P. Meares, Etty N. Benveniste · 2014 · Springer eBooks
12. Role of Reactive Astrocytes in Alzheimer’s Disease
    Sukanya Sarkar, Subhalakshmi Guha, Subhas Chandra Biswas · 2022 · Springer eBooks
13. Roles in Innate Immunity
    Kaira A. Church, Astrid E. Cardona, Sarah C. Hopp · 2024 · Advances in neurobiology
14. Autophagy and Age-Related Diseases
    丹 赵 · 2017 · Hans Journal of Biomedicine
15. Insulin resistance and Alzheimer’s disease
    A. A. Farooqui · 2020 · Elsevier eBooks
16. Cognitive Impairment in Diabetes Mellitus and Its Management by Transcription Factor Nrf2-Mediated Antioxidant Defense System
    Xian Zhou, Gerald W Münch, Dennis Chang · 2022 · Biochemistry
17. The Role of ATP and P2X Purinoceptor 7 in the Development of Cerebral Tau
    Andrew F. Gao · 2018 · TSpace (University of Toronto)
18. Chronic IL-1-induced DNA double-strand break response in hippocampal neurons drives cognitive deficits
    Marcy Belloy, Benjamin A. M. Schmitt, Florent H. Marty, Charlotte Paut, Bassot-Parra Emilie, Amel Aïda, Marine Alis, Romain Ecalard, Raphaël Boursereau, Daniel Gonzalez‐Dunia et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
19. The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly people
    Tovia Jacobs, Sean R. Jacobson, Juan Fortea, Jeffrey S. Berger, Alok Vedvyas, Karyn Marsh, Tianshe He, Eugenio Gutiérrez‐Jiménez, Nathanael R. Fillmore, Omonigho M. Bubu et al. · 2024 · Research Square
20. Dyrk1a inhibition with the Novel Compound DYR533: A Cross-Disease Therapeutic Strategy Targeting Amyloidosis, Tau Pathogenesis, and Neuroinflammation
    Samantha K. Bartholomew, Julie Turk, Wendy Winslow, Christopher Foley, Arthur Y. Shaw, Samantha Rokey, Savannah Tallino, Jessica M. Judd, Thomas G. Beach, Geidy E. Serrano et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
21. Novelly Synthesized Coumarin Derivative as a Pro-inflammatory Cytokines Inhibitor
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22. Using TUDCA to treat Alzheimer's disease after pathology onset in APP/PS1 mice
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23. Mechanisms of palmitate induced amyloidogenesis in Alzheimer's Disease mediated by astrocytes
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24. Review Article Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders
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25. Using TUDCA to treat Alzheimer's disease after pathology onset in APP/PS1 mice
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26. Intraneuronal Amyloid and Inflammation
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27. The Role of Astrocytic Calcineurin Activation and Downstream Signaling in Neurodegenerative Diseases
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28. Nitric Oxide Donors in Brain Inflammation
    Marisol Godínez-Rubí, Daniel Ortuño‐Sahagún · 2017 · Elsevier eBooks
29. Treatment Mechanisms in Mild to Moderate Alzheimer’s Disease
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30. Investigating the contribution of astrocytes and neuroinflammation to pathological tau changes in Alzheimer's disease
    Emma Claire Phillips · 2017 · Research Portal (King's College London)
31. Sustained Interleukin-1β overexpression exacerbates Tau pathology in a murine tauopathy model via cyclooxygenase-1
    Simantini Ghosh, Solomon S. Shaftel, Stephanos Kyrkanides, John A. Olschowka, M. Kerry O’Banion · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
32. Biomarkers of Agitation in Patients with Alzheimer's disease
    Myuri T. Ruthirakuhan · 2019 · TSpace (University of Toronto)
33. The Role of Microglial-Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) in Neuronal Homeostasis and Tau Pathogenesis
    Vaishnavi Jadhav · 2021 · IUScholarWorks (Indiana University)
34. Narratives of Neurology: Exploring the Broken Brain Through Interview
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35. References
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37. Infection-Induced Systemic Inflammation and Dementia
    Newman Osafo, Silvio Owusu Dei, Nathanael Adote Akwei, Kofi Oduro Yeboah · 2022 · Springer eBooks
38. Neuroprotective effect of intranasal delivery of asiatic acid against amyloid beta1-42-induced alzheimer's disease in mice
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39. A Neuroinflammatory View of Alzheimer’s Disease
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41. PGRN Counteracts the Associations of Abnormal Tau Proteins with Neurodegeneration and Cognitive Decline in Non-demented Adults: A Longitudinal Study
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42. Mature tau pathology is not improved by interfering with interleukin-1 receptor signaling in two mouse models of tauopathy
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43. Anti-inflammatory and immunomodulating agents
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44. Additional file 1 of The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly people
    Tovia Jacobs, Sean R. Jacobson, Juan Fortea, Berger, Jeffrey S., Alok Vedvyas, Karyn Marsh, Tianshe He, Eugenio Gutiérrez‐Jiménez, Nathanael R. Fillmore, Moses Gonzalez et al. · 2024 · Figshare
45. Targeting Neuroinflammation in Alzheimer's Disease: Repurposed Nucleoside Reverse Transcriptase Inhibitors and the Therapeutic Potential of Kamuvudine‐9
    Mariyam Hussain, Mohammad Ikram, Divya Vohora · 2026 · Fundamental and Clinical Pharmacology
46. Etudes de trois métalloprotéases matricielles, MT1-MMP, MT5-MMP et MMP-12 dans l'amyloïdogenèse et les atteintes inflammatoires et vasculaires associées à la maladie d'Alzheimer
    Amandine Bonnet · 2017 · theses.fr (ABES)
47. Characterisation de l’ubiquitine Ligase PDZRN3 en tant que nouvel acteur des voies Wnt dans la morphogenese et l’integrite vasculaire
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48. Plasticity of hippocampal synaptic transmission and intrinsic excitability in a mouse model of Alzheimer’s disease
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49. Molecular mechanisms of action of MT-MMPs involved in the pathogenesis of Alzheimer’s disease
    Laura García‐González · 2020 · theses.fr (ABES)
50. Métalloprotéases matricielles et maladie d'Alzheimer : étude des rôles de MT1- et MT5-MMP dans l'amyloïdogenèse et la neuro-inflammation
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51. Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie
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53. MT5-MMP promotes neuroinflammation, pathogenic processing of amyloid precursor protein and synaptic dysfunction at early stages in an Alzheimer's disease model
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57. Visceral adipose tissue differentially affects tau and Aβ pathology in 3xTg-AD mice
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58. Microglial synaptic pruning in early Alzheimer’s disease: emerging roles of the IL-1β-NLRP3 axis
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63. Elevated DYRK1A in Primary Tauopathies and Therapeutic Targeting with the Brain-Penetrant Inhibitor DYR533
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