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Cited by 420

The DOI matches its Crossref record.

Reticulum Cell Sarcoma: An Effector Cell in Antibody-Dependent Cell-Mediated Immunity

Ralph, Peter, Prichard, John, Cohn, Melvin·1975·The Journal of Immunology

Abstract

A transplantable, murine reticulum cell sarcoma is described which exhibits the cytologic, adherence, and phagocytic properties of macrophages. It forms specific rosettes with erythrocytes in the presence of the corresponding anti-serum. The ascites cells mediate antibody-dependent cellular immunity as assayed by release of radioactivity from 51Cr-labeled erythrocytes. The contribution of contaminating host cells in the cytotoxic reaction was ruled out by growing the tumor in F1 mice and removing the host cells by anti-H2 serum and complement. The tumor cells have receptors for IgG2a and IgG2b immunoglobulins. The availability of a pure population of effector cells in the immune system allows study of the biochemical processes pursuant to lysis of foreign cells.

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Crossref · 10.4049/jimmunol.114.2_part_2.898

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Metadata

Authors
Ralph, P., Prichard, J., & Cohn, M.
Venue
The Journal of Immunology
Published
1975-02-01
Volume
114
Issue
2_Part_2
Pages
898-905
ISSN
  • 0022-1767 (ISSN-L)
  • 1550-6606
OpenAlex
W1936480433
Cited by
420
References
0
FWCI
4.55
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Reticulum Cell Sarcoma: An Effector Cell in Antibody-Dependent Cell-Mediated Immunity. https://app.cochat.ai/papers/10.4049/jimmunol.114.2_part_2.898
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Ralph, P., Prichard, J., & Cohn, M. (1975). Reticulum Cell Sarcoma: An Effector Cell in Antibody-Dependent Cell-Mediated Immunity. The Journal of Immunology. https://doi.org/10.4049/jimmunol.114.2_part_2.898

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.