Preferential species-restricted heavy/light chain pairing in rat/mouse quadromas. Implications for a single-step purification of bispecific antibodies

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Items 101–200 of 214

1. Bispecific Antibody-Based Immune-Cell Engagers and Their Emerging Therapeutic Targets in Cancer Immunotherapy
   Ha Gyeong Shin, Ha Rim Yang, Aerin Yoon, Sukmook Lee · 2022 · International Journal of Molecular Sciences
2. Trioma-based vaccination against B-cell lymphoma confers long-lasting tumor immunity.
   Ralph Mocikat, Michael Selmayr, S Thierfelder, Horst Lindhofer · 1997 · PubMed
3. Use of trifunctional bispecific antibodies to prevent graft versus host disease induced by allogeneic lymphocytes
   Shoshana Morecki, Horst Lindhofer, Elena Yacovlev, Yael Gelfand, Shimon Slavin · 2005 · Blood
4. Bispecific Antibodies: A Novel Approach for the Treatment of Solid Tumors
   Luigi Liguori, Giovanna Polcaro, Annunziata Nigro, Valeria Conti, Carmine Sellitto, Francesco Perri, Alessandro Ottaiano, Marco Cascella, Pio Zeppa, Alessandro Caputo et al. · 2022 · Pharmaceutics
5. Bispecific antibodies target operationally tumor-specific antigens in two leukemia relapse models
   Horst Lindhofer, Helge Menzel, Wilfried Günther, Lothar Hültner, S. Thierfelder · 1996 · Blood
6. The current status of immunotherapy in peritoneal carcinomatosis
   Michael Alfred Ströhlein, M. M. Heiss, Karl‐Walter Jauch · 2016 · Expert Review of Anticancer Therapy
7. Anti-Idiotype × Anti-CD44 Bispecific Antibodies Inhibit Invasion of Lymphoid Organs by B Cell Lymphoma
   Esther Avin, Joseph Haimovich, Nurit Hollander · 2004 · The Journal of Immunology
8. Controlled conductivity at low pH in Protein L chromatography enables separation of bispecific and other antibody formats by their binding valency
   Chen Chen, Tetsuya Wakabayashi, Masaru Muraoka, Shu Feng, Chia Wei Shan, Chong Chor Kun, Ching Tim Jang, Ishin Soehano, Yuichiro Shimizu, Tomoyuki Igawa et al. · 2019 · mAbs
9. Revolutionizing cancer immunotherapy: unleashing the potential of bispecific antibodies for targeted treatment
   Xiaohan Guo, Yi Wu, Xue Ying, Na Xie, Guobo Shen · 2023 · Frontiers in Immunology
10. Single-step Protein A and Protein G avidity purification methods to support bispecific antibody discovery and development
    Romain Ollier, Paul Wassmann, Thierry Monney, Christelle Ries Fecourt, Sunitha Gn, Chaithanya Vinu, Daniel Ayoub, Cian Stutz, Girish S. Gudi, Stanislas Blein · 2019 · mAbs
11. Aptamers as potential therapeutic agents for ovarian cancer
    Justin Henri, Joanna Petrasek MacDonald, Mia Strom, Wei Duan, Sarah L. Shigdar · 2017 · Biochimie
12. Antitumor Immunity: Easy as 1, 2, 3 with Monoclonal Bispecific Trifunctional Antibodies?
    John F. Maher, Antonella A. Adami · 2013 · Cancer Research
13. A review on emerging targeted therapies for the management of metastatic colorectal cancers
    Rohitas Deshmukh, Mahendra Kumar Prajapati, Ranjit Kumar Harwansh · 2023 · Medical Oncology
14. The Trifunctional Antibody Catumaxomab in Treatment of Malignant Ascites and Peritoneal Carcinomatosis
    Michael Alfred Ströhlein, M. M. Heiss · 2010 · Future Oncology
15. Immunotherapy of B‐cell non‐Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model
    Hossein Panjideh, Gerd Müller, Mathias Koch, Frank Wilde, Susanne Scheu, Gerhard Moldenhauer, Martin Lipp · 2014 · International Journal of Cancer
16. Cloning, expression, purification and characterization of a bispecific single-chain diabody against fluoroquinolones and sulfonamides in Escherichia coli
    Min Chen, Kai Wen, Xiaoqi Tao, Jie Xie, Limiao Wang, Yang Li, Shuangyang Ding, Haiyang Jiang · 2014 · Protein Expression and Purification
17. An efficient process of generating bispecific antibodies via controlled Fab-arm exchange using culture supernatants
    Suparna Paul, Judy Connor, Tom Nesspor · 2016 · Protein Expression and Purification
18. Excellent removal of knob-into-hole bispecific antibody byproducts and impurities in a single-capture chromatography
    Serene W. Chen, Kong Meng Hoi, Farouq Bin Mahfut, Yuansheng Yang, Wei Zhang · 2022 · Bioresources and Bioprocessing
19. Combined treatment of metastatic breast cancer (MBC) by high-dose chemotherapy (HDCT) and bispecific antibodies: a pilot study.
    Hans‐Joachim Stemmler, Christoph Salat, Horst Lindhofer, Helge Menzel, Michael Untch, Steffen Kahlert, G. Konecny, Hansjörg Sauer, Georg Ledderose, Volker Heinemann et al. · 2005 · PubMed
20. The making of multispecific immunoglobulins – a clinical perspective
    Ulrich Brinkmann, Roland E. Kontermann · 2026 · mAbs
21. Engineered Bifunctional Proteins for Targeted Cancer Therapy: Prospects and Challenges
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22. Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor Therapy
    Shixue Chen, Lingling Li, Fan Zhang, Yu Wang, Yi Hu, Lei Zhao · 2019 · Journal of Immunology Research
23. Characterization of a Unique Anti-DNA Hybridoma
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24. Gene therapy of B-cell lymphoma with cytokine gene-modified trioma cells
    John Strehl, Michael Selmayr, Jean‐P. Kremer, Lothar H�ltner, Horst Lindhofer, Ralph Mocikat · 1999 · International Journal of Cancer
25. Efficient bispecific monoclonal antibody purification using gradient thiophilic affinity chromatography
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26. Bispecific Antibody Derivatives Based on Full-Length IgG Formats
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27. Impact of the lymphoma idiotype on in vivo tumor protection in a vaccination model based on targeting antigens to antigen-presenting cells
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28. Specific targeting of whole lymphoma cells to dendritic cells ex vivo provides a potent antitumor vaccine
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29. Engineered polyspecific antibodies: A new frontier in the field of immunotherapeutics
    Sandeep, Suraj H. Shinde, Sakeel Ahmed, Shyam Sunder Sharma, Abhay H. Pande · 2023 · Immunology
30. A dual-targeting triplebody mediates preferential redirected lysis of antigen double-positive over single-positive leukemic cells
    Ingo A. Schubert, Domenica Saul, Stefanie Nowecki, Andréas Mackensen, Georg H. Fey, Fuat S. Oduncu · 2013 · mAbs
31. Protein engineering and the use of molecular modeling and simulation: The case of heterodimeric Fc engineering
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32. Rationale and development of multispecific antibody drugs
    Jijie Gu, Tariq Ghayur · 2010 · Expert Review of Clinical Pharmacology
33. Application of bispecific antibody against antigen and hapten for immunodetection and immunopurification
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34. The evolving role of catumaxomab in gastric cancer
    Florian Lordick, Katja Ott, Jürgen Weitz, Dirk Jäger · 2008 · Expert Opinion on Biological Therapy
35. To Market, To Market—2009
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36. Trifunctional bispecific antibody–induced tumor cell lysis of squamous cell carcinomas of the upper aerodigestive tract
    Silke Gronau, Michael W. Schmitt, Bernard Thess, Peter Reinhardt, Markus Wiesneth, Anita Schmitt, Herbert Riechelmann · 2005 · Head & Neck
37. A detergent-based procedure for the preparation of IgG-like bispecific antibodies in high yield
    Jyoti Gupta, Mehboob Hoque, Masihuz Zaman, Rizwan Hasan Khan, Mohammed Saleemuddin · 2016 · Scientific Reports
38. Trifunctional Triomab® Antibodies for Cancer Therapy
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39. Immunotherapy of Peritoneal Carcinomatosis
    Michael Alfred Ströhlein, M. M. Heiss · 2007 · Springer eBooks
40. Affinity chromatography and co-chromatography of bispecific monoclonal antibody immunoconjugates
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41. Introduction: Antibody Structure and Function
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42. A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties
    Jie Zhao, Liangfeng Jiang, Haodong Yang, Lan Deng, Xiaoqing Meng, Jian Ding, Sixing Yang, Le Zhao, Wei Xu, Xiaolong Wang et al. · 2022 · mAbs
43. Effective flow-through polishing strategies for knob-into-hole bispecific antibodies
    Serene W. Chen, Kong Meng Hoi, Farouq Bin Mahfut, Yuansheng Yang, Wei Zhang · 2022 · Bioresources and Bioprocessing
44. Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2
    Rupal Ojha, Kiran Gurjar, Tadi Sai Ratnakar, Amit Mishra, Vijay Kumar Prajapati · 2022 · Human Immunology
45. Bispezifische Antikörper
    M. A. Ströhlein, M. M. Heiss · 2012 · Der Onkologe
46. Antitumour effects of a bispecific trivalent antibody in multicellular tumour spheroids.
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47. Development of Bispecific Molecules for the In Situ Detection of Protein-Protein Interactions and Protein Phosphorylation
    Jan van Dieck, Volker Schmid, Dieter Heindl, Sebastian Dziadek, Michael Schräml, Michael Gerg, Petra Massoner, Alfred Michael Engel, Georg Tiefenthaler, Serhat Vural et al. · 2014 · Chemistry & Biology
48. Bispecific Antibodies
    Dafne Müller, Roland E. Kontermann · 2007 · Wiley eBooks
49. Solid-Phase Bioconjugation of Heterobifunctional Adaptors for Versatile Assembly of Bispecific Targeting Ligands
    Hong Yan Liu, Pavel Zrazhevskiy, Xiaohu Gao · 2014 · Bioconjugate Chemistry
50. Potential of the Trifunctional Bispecific Antibody Surek Depends on Dendritic Cells: Rationale for a New Approach of Tumor Immunotherapy
    Nina Eißler, Josef Mysliwietz, Nina Deppisch, Peter Ruf, Horst Lindhofer, Ralph Mocikat · 2013 · Molecular Medicine
51. DOWNSTREAM PROCESSING OF Fc FUSION PROTEINS, BISPECIFIC ANTIBODIES, AND ANTIBODY–DRUG CONJUGATES
    Abhinav A Shukla, Carnley Norman · 2017
52. Bispecific Antibodies
    Dafne Müller, Roland E. Kontermann · 2014 · Wiley eBooks
53. Mechanism-Driven Design of Multispecific Antibodies for Targeted Disease Treatment
    Justyn Fine, Bunyarit Meksiriporn, Jiacheng Tan, Jamie B. Spangler · 2024 · Annual Review of Chemical and Biomolecular Engineering
54. Leveraging light chain binding avidity for control of mispaired byproducts during production of asymmetric bispecific antibodies
    Kamiyar Rezvani, Dominique WuDunn, Alan K. Hunter · 2022 · Journal of Chromatography A
55. Bispecific Antibodies: Developments and Current Perspectives
    Roland E. Kontermann · 2011 · Springer eBooks
56. The mosaic puzzle of the therapeutic monoclonal antibodies and antibody fragments - A modular transition from full-length immunoglobulins to antibody mimetics
    Sami El Khatib, Mohamed Salla · 2022 · Leukemia Research Reports
57. Bispecific Antibodies from Hybrid Hybridoma
    Gerhard Moldenhauer · 2011 · Springer eBooks
58. Optimization of a Novel 2 + 2 BCMA × CD3 Bispecific Antibody for Minimized Cytokine Release and Potent Efficacy
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59. Bispecific Antibody Armed T Cells to Target Cancer Cells
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60. Bispecific Antibodies
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61. Prednisolone reduces TNF-alpha release by PBMCs activated with a trifunctional bispecific antibody but not their anti-tumor activity.
    Annette Walz, Michaela Andratschke, Barbara Wollenberg, Horst Lindhofer, Reinhard Zeidler · 2005 · PubMed
62. The safety and efficacy of bispecific T-cell engagers (TCEs) in patients with glioma
    Behrouz Robat-Jazi, Parsa Lorestani, Negar Nejati, Elaheh Ebrahimi, Mohammad Amin Habibi, Mahsa Ahmadpour, Armita Jokar-Derisi, Zahra Karimizadeh, Kamyar Bagheri, Sajjad Ahmadpour · 2026 · Clinical and Experimental Medicine
63. Understanding the structure–property relationship of bispecific monoclonal antibodies with Fc site-specific substitutions
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64. Effector Cell Recruitment by Bispecific Antibodies
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65. Role of β-microseminoprotein from prostate cancer initiation to recurrence: A mini-review
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66. Engineering antibodies for dual specificity and enhanced potency
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67. The Swinging Pendulum of Cancer Immunotherapy Personalization
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68. T-cell engaging bispecific antibody therapy
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69. Antibody engineering: Molecular constructor on the basis of barnase-barstar module
    Sergey Mikhailovich Deyev, Ekaterina N. Lebedenko · 2009 · Russian Journal of Bioorganic Chemistry
70. Bispecific antibodies: A promising entrant in cancer immunotherapy
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71. Bispecific Antibodies and Immune Therapy Targeting
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72. Resurgence of Bispecific Antibodies
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73. T Lymphocytes with Modified Specificity in the Therapy of Malignant Diseases
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74. Recombinant Bispecific Antibodies for Cancer Therapy
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75. Acid pH promotes bispecific antibody formation by the redox procedure
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76. Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review)
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77. Les anticorps bispécifiques : une vieille histoire pleine d’avenir… avec les CAR-T !
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78. Strand Exchange Engineered Domain (Seed): A Novel Platform Designed to Generate Mono and Multispecific Protein Therapeutics
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79. Antibody Fc engineering for optimal antibody performance
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80. Multiple antibody and multi-specificity approaches
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81. Two-in-One Antibodies
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82. Producing and prospects for the use of bispecific antibodies for the treatment of cancer
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83. Personalized Medicine
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84. References
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85. Analytical Characterization of Bispecific Antibodies and Bispecific Molecules
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86. Bispecific Antibodies for the Treatment of Cancer: The Challenges of Translation
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87. Catumaxomab (Removab) – Trifunctional Antibodies: Combining Direct Tumor Cell Killing with Therapeutic Vaccination
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89. Bifunctional Antibodies: Preclinical and Clinical Applications
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90. Antibody-based cancer therapy
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91. Advances in Bispecific Antibodies Engineering: Novel Concepts for
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92. Passive immunotherapy by T cell–engaging bispecific antibodies
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93. Characterization of Bispecific or Other Hybrid Molecules
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94. IPEC, HIPEC, PIPAC, bidirektionale Chemotherapie und Immuntherapie bei Komplikationen der Peritonealkarzinose
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95. Translational Considerations in Developing Bispecific Antibodies: What Can We Learn from Quantitative Pharmacology?
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96. The research and development of bispecific antibodies
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97. IPEC, HIPEC, Bidirectional Chemotherapy, and Immunotherapy in Aggressive Peritoneal Metastasis
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98. Faculty Opinions recommendation of Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics.
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99. Quadroma (Hybrid Hybridoma)
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