The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Surfactant Protein D Enhances Clearance of Influenza A Virus from the Lung In Vivo
Open accessAbstract
Mice lacking surfactant protein surfactant protein D (SP-D−/−) and wild-type mice (SP-D+/+) were infected with influenza A virus (IAV) by intranasal instillation. IAV infection increased the endogenous SP-D concentration in wild-type mice. SP-D-deficient mice showed decreased viral clearance of the Phil/82 strain of IAV and increased production of inflammatory cytokines in response to viral challenge. However, the less glycosylated strain of IAV, Mem/71, which is relatively resistant to SP-D in vitro, was cleared efficiently from the lungs of SP-D−/− mice. Viral clearance of the Phil/82 strain of IAV and the cytokine response were both normalized by the coadministration of recombinant SP-D. Since the airway is the usual portal of entry for influenza A virus and other respiratory pathogens, SP-D is likely to play an important role in innate defense responses to IAV.
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Immunomodulatory functions of surfactant
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Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus
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Self-citationDistinct Effects of Surfactant Protein A or D Deficiency During Bacterial Infection on the Lung
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Self-citationEvidence for a protective role of pulmonary surfactant protein D (SP-D) against influenza A viruses.
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Self-citationSurfactant Protein-D Regulates Surfactant Phospholipid Homeostasis in Vivo
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Cited by
Immunoregulatory functions of surfactant proteins
Wright, J. R. (2005) · Nature Reviews Immunology · doi:10.1038/nri1528 · Cited by 964
Collectins and Ficolins: Humoral Lectins of the Innate Immune Defense
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Surfactant proteins SP-A and SP-D: structure, function and receptors
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GM-CSF in the lung protects against lethal influenza infection
Huang, F.-F., Barnes, P. F., Feng, Y., Donis, R., Chroneos, Z. C., Idell, S., Allen, T., Perez, D. R., Whitsett, J. A., Dunussi-Joannopoulos, K., et al. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201012-2036oc · Cited by 161
Self-citationBitter-sweet symphony: glycan–lectin interactions in virus biology
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Metadata
- Authors
- LeVine, A. M., Whitsett, J. A., Hartshorn, K. L., Crouch, E. C., & Korfhagen, T. R.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-11
- Volume
- 167
- Issue
- 10
- Pages
- 5868-5873
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1553440365
- Cited by
- 277
- References
- 33
- FWCI
- 10.22
- Type
- journal article
- Language
- en
- Open access
- bronze
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- LeVine, A. M., Whitsett, J. A., Hartshorn, K. L., Crouch, E. C., & Korfhagen, T. R. (2001). Surfactant Protein D Enhances Clearance of Influenza A Virus from the Lung In Vivo. The Journal of Immunology. https://doi.org/10.4049/jimmunol.167.10.5868
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