LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition
van den Berg, Timo K, Honing, Henk, Franke, Niels, van Remoortere, Alexandra, Schiphorst, Wietske E C M, Liu, Fu-Tong, Deelder, André M, Cummings, Richard D +2 more·2004·The Journal of Immunology
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- Galectins in Host Defense Against Microbial InfectionsFang-Yen Li, Sheng‐Fan Wang, Emerson Soares Bernardes, Fu‐Tong Liu · 2020 · Advances in experimental medicine and biology
- Diagnostic and Prognostic Significance of Serum and Tissue Galectin 3 Expression in Patients with Carcinoma of the BladderHoda El Gendy, Bothina Madkour, Sara Abdelaty, Fayza Essawy, Dina W. Khattab, O. Hammam, H. Nour · 2014 · Current Urology
- Immunomodulatory Glycan Lacto-N-Fucopentaose III Requires Clathrin-Mediated Endocytosis To Induce Alternative Activation of Antigen-Presenting CellsL. Srivastava, Smanla Tundup, Beak-San Choi, T. Norberg, D. Harn · 2014 · Infection and Immunity
- Protein glycosylation and glycoinformatics for novel biomarker discovery in neurodegenerative diseasesJúlia Costa, Catherine A. Hayes, Frédérique Lisacek · 2023 · Ageing Research Reviews
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- Galectins, Eosinophiles, and Macrophages May Contribute to Schistosoma japonicum Egg-Induced Immunopathology in a Mouse ModelZhanhong Ye, Shi-Guang Huang, Yanxia Zhang, Xu Mei, Huan-Qin Zheng, Meiyu Li, Jian-Hua Chen, Fang-Li Lu · 2020 · Frontiers in Immunology
- Lack of galectin-3 up-regulates IgA expression by peritoneal B1 lymphocytes during B cell differentiationF. Oliveira, E. Bernardes, C. Brand, S. D. dos Santos, M. Cabanel, Kátia D. Arcanjo, J. Brito, R. Borojevic, R. Chammas, M. C. El-Cheikh · 2016 · Cell and Tissue Research
- Lack of Galectin-3 Disturbs Mesenteric Lymph Node Homeostasis and B Cell Niches in the Course of Schistosoma mansoni InfectionF. Oliveira, C. Brand, A. Paula, Kátia D. Arcanjo, D. Hsu, Fu-Tong Liu, C. Takiya, R. Borojevic, R. Chammas, M. C. El-Cheikh · 2011 · PLoS ONE
- Intestinal lymphatic transport of Smilax china L. pectic polysaccharide via Peyer's patches and its uptake and transport mechanisms in mononuclear phagocytes.Jun-Xi Liu, Xiaoke Zhang, Yan Liu, Zhi-Jing Wu, Zheng Cui, Xianglin Pan, Yuheng Zheng, Jing-Lin Wang, Kai-Ping Wang, Yu Zhang · 2024 · Carbohydrate Polymers
- Novel O -linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrusJames P. Hewitson, D. Linh Nguyen, Angela van Diepen, Cornelis H. Smit, Carolien A. M. Koeleman, Henry J. McSorley, Janice Murray, Rick M. Maizels, Cornelis Hendrik Hokke · 2015 · International Journal for Parasitology
- Lack of galectin‐3 involvement in murine intestinal nematode and schistosome infectionQuentin D Bickle, Helena Helmby · 2006 · Parasite Immunology
- Breast Milk Oligosaccharides Contain Immunomodulatory Glucuronic Acid and LacdiNAcC. Jin, Jon Lundstrøm, E. Korhonen, A. S. Luis, Daniel Bojar · 2023 · bioRxiv
- Unique glycan and lipid composition of helminth-derived extracellular vesicles may reveal novel roles in host-parasite interactions.B. Whitehead, A. Boysen, Maibritt Mardahl, P. Nejsum · 2020 · International Journal of Parasitology
- Endogenous galectin‐3 controls experimental malaria in a species‐specific mannerM. Toscano, J. Tongren, J. D. de Souza, F.-T. Liu, E. Riley, G. Rabinovich · 2012 · Parasite immunology (Print)
- Development of a Sensitive Microarray Platform for the Ranking of Galectin Inhibitors: Identification of a Selective Galectin‐3 InhibitorJ. Dion, Tamara Advedissian, Nataliya Storozhylova, Samir Dahbi, Annie Lambert, Frédérique Deshayes, M. Viguier, C. Tellier, F. Poirier, Stéphane Téletchéa et al. · 2017 · ChemBioChem
- Biochemical Characterization of Oyster and Clam Galectins: Selective Recognition of Carbohydrate Ligands on Host Hemocytes and Perkinsus ParasitesG. Vasta, C. Feng, Satoshi Tasumi, Kelsey Abernathy, M. Bianchet, I. Wilson, Katharina Paschinger, Lai-Xi Wang, Muddasar Iqbal, Anita Ghosh et al. · 2020 · Frontiers in Chemistry
- Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3S. Böcker, L. Elling · 2017 · Bioengineering
- Mucosal Immunity of Major Gastrointestinal Nematode Infections in Small Ruminants Can Be Harnessed to Develop New Prevention StrategiesP. G. A. S. Palkumbura, T. A. Mahakapuge, R. R. M. K. Kavindra Wijesundera, V. Wijewardana, R. Kangethe, R. P. V. Jayanthe Rajapakse · 2024 · International Journal of Molecular Sciences
- Galectin isolated from parasite inhibits remission of experimental autoimmune encephalomyelitis by up‐regulating autoantibodyS. Bing, Danbee Ha, Ginnae Ahn, Jinhee Cho, A. Kim, Sang Kyun Park, Hak-Sun Yu, Y. Jee · 2015 · Clinical and Experimental Immunology
- Structural insights into the molecular recognition mechanism of the cancer and pathogenic epitope, LacdiNAc by immune-related lectins.Carlos D. L. Lima, Helena Coelho, A. Gimeno, F. Trovão, A. Diniz, Jorge S Dias, J. Jiménez-Barbero, F. Corzana, A. Carvalho, E. Cabrita et al. · 2021 · Chemistry
- N-Glycosylation is required for secretion of the precursor to brain-derived neurotrophic factor (proBDNF) carrying sulfated LacdiNAc structuresJúlius Benický, Miloslav Šanda, Zuzana Brnáková, Radoslav Goldman · 2019 · Journal of Biological Chemistry
- Galectin-2 suppresses nematode development by binding to the invertebrate-specific galactoseβ1-4fucose glyco-epitope.T. Takeuchi, M. Tamura, K. Ishiwata, Megumi Hamasaki, S. Hamano, Y. Arata, T. Hatanaka · 2019 · Glycobiology
- Structure elucidation of NeuAc, NeuGc and Kdn-containing O-glycans released from Triturus alpestris oviductal mucinsDoina Florea, E. Maes, Y. Guérardel, A. Page, J. Zanetta, D. Cogǎlniceanu, G. Strecker · 2006 · Glycoconjugate Journal
- Brugia malayi galectin 2 is a tandem-repeat type galectin capable of binding mammalian polysaccharidesMarla I. Hertz, Philip M Glaessner, Amy C. Rush, Philip J. Budge · 2019 · Molecular and biochemical parasitology (Print)
- Trefoil Factor Family Domains Represent Highly Efficient Conformational Determinants for N-Linked N,N′-di-N-acetyllactosediamine (LacdiNAc) Synthesis*D. Bonar, F. Hanisch · 2014 · Journal of Biological Chemistry
- Glycan-binding profile and cell adhesion activity of American bullfrog (Rana catesbeiana) oocyte galectin-1.S. Kawsar, R. Matsumoto, Y. Fujii, H. Yasumitsu, H. Uchiyama, M. Hosono, K. Nitta, J. Hamako, T. Matsui, N. Kojima et al. · 2009 · Protein Peptide Letters
- Mass Spectrometrical Analysis of Galectin Proteins in Primary Rat Cerebellar AstrocytesJ.-W. Yang, S. U. Kang, E. Engidawork, R. Rodrigo, V. Felipo, G. Lubec · 2006 · Neurochemical Research
- N‐Glycan profiling of chondrocytes and fibroblast‐like synoviocytes: Towards functional glycomics in osteoarthritisJohannes Fuehrer, K. Pichler, A. Fischer, A. Giurea, D. Weinmann, F. Altmann, R. Windhager, H. Gabius, S. Toegel · 2021 · PROTEOMICS - Clinical Applications
- Enhanced expression of the β4-N-acetylgalactosaminyltransferase 4 gene impairs tumor growth of human breast cancer cellsKiyoko Hirano, Akio Matsuda, Ryo Kuji, Shiro Nakandakari, Takashi Shirai, Kiyoshi Furukawa · 2015 · Biochemical and Biophysical Research Communications
- Immune Recognition of Parasite GlycansR. Maizels, James P. Hewitson · 2012 · Springer eBooks
- Lectin in Host Defense Against Microbial InfectionsShie-Liang Hsieh Editor, Wim E Crusio, John D Lambris, S. Hsieh · 2020
- Galectin-receptor interaction: a key player in liver fibrosis induced by Schistosoma japonicum infectionZiyun Huang, Xing-Zhuo Liu, Shi-Guang Huang, Fang-Li Lu · 2024 · Parasites & Vectors
- Glycomics in unravelling glycan-driven immune responses by parasitic helminthsI. van Die, R. Cummings · 2009 · Elsevier eBooks
- Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactationChunsheng Jin, Jon Lundstrøm, Carmen R. Cori, Shih-Yun Guu, Alexander R. Bennett, M. Dannborg, P. Pomeroy, M. Kennedy, J. Bengtsson-Palme, Rachel Hevey et al. · 2025 · bioRxiv
- Synthesis of GalNAcβ1-4GlcNAcβ (LacdiNAc) O-sulfatesG. Pazynina, M. Sablina, V. Nasonov, Y. Pustovalova, I. Belyanchikov, N. Bovin · 2010
- Galectin-3: Forms, Functions, and Clinical ManifestationsAnita Gupta · 2012 · Springer eBooks
- Diversity-Oriented Enzymatic Modular Synthesis of N-Glycans Bearing LacdiNAc-Related Epitopes.Xuefei Yin, Xiaoying Zhang, Kan Zhong, Hai-Long Wang, Zhi-Fei Hu, Chang-Cheng Liu, Hong-Zhi Cao · 2025 · Organic Letters
- Fatty-binding protein and galectin of Baylisascaris schroederi: Prokaryotic expression and preliminary evaluation of serodiagnostic potentialYing Sun, Y. Li, Yiran Wu, L. Xiong, Cai-Wu Li, Cheng-Dong Wang, Desheng Li, Jing-Chao Lan, Zhihe Zhang, Bo Jing et al. · 2017 · PLoS ONE
- Interaction of schistosome glycans with the host immune system.I. van Die, E. van Liempt, C. Bank, W. Schiphorst · 2005 · Advances in Experimental Medicine and Biology
- Galectin-3 plays a key role in controlling infection by Toxoplasma gondii in human trophoblast cells and human villous explantsL. C. Luz, Mayara Ribeiro, S. Teixeira, Guilherme De Souza, Marina Paschoalino, Daniel Pereira Sousa, A. Rosini, Natália Carine Lima dos Santos, R. D. de Oliveira, J. P. de Lima et al. · 2024 · Frontiers in Cellular and Infection Microbiology
- Lectin-Based Immunophenotyping and Whole Proteomic Profiling of CT-26 Colon Carcinoma Murine ModelA. Faragó, Á. Zvara, László Tiszlavicz, Éva Hunyadi-Gulyás, Zsuzsanna Darula, Zoltán Hegedűs, E. Szabó, Sára Surguta, J. Tóvári, László G. Puskás et al. · 2024 · International Journal of Molecular Sciences
- Galectins in Protozoan Parasitic Diseases: Potential Applications in Diagnostics and TherapeuticsC. Meira, Jaqueline Silva, H. Quadros, L. Silva, B. Barreto, V. Rocha, L. Bomfim, E. Santos, M. Soares · 2023 · Cells
- In vitro evaluation of the effect of galectins on Schistosoma mansoni motilityT. Takeuchi, Risa Nakamura, Megumi Hamasaki, Midori Oyama, Shinjiro Hamano, Tomomi Hatanaka · 2023 · BMC Research Notes
- Galectin-3 and Regulation of Cell FunctionDaniel K. Hsu, Ichiro Kuwabara, Fu‐Tong Liu · 2005 · Transfusion Medicine and Hemotherapy
- Distribution, biosynthesis, recognition, identification and biological functions of LacdiNAc structures on N- and O- glycans: A review.Yingjie Zhang, Lei Wu, Xiaorui Liu, Xiaotong Chen, Jun Li · 2025 · International Journal of Biological Macromolecules
- Investigation of N-Acetyllactosamine and N,N-Diacetyllactosamine Residues of Seminal Plasma Prolactin-Induced Protein as Ligands Recognized by Galectin-3Anna Kałuża, K. Trzęsicka, Damian Drzyzga, M. Ferens-Sieczkowska · 2024 · International Journal of Molecular Sciences
- Innate immune receptors are differentially expressed in mice during experimental Schistosoma mansoni early infectionJ. Lima, Ramayana Morais de Medeiros Brito, Luanderson Cardoso Pereira, Nathalie de Sena Pereira, Manuela Sales Lima Nascimento, A. L. de Melo, P. M. M. Guedes · 2024 · Memórias do Instituto Oswaldo Cruz
- Sex-specific glycosylation of secreted immunomodulatory proteins in the filarial nematode Brugia malayiJoseph Koussa, Burcu Vitrinel, Peter H. Whitney, B. Kasper, L. Mahal, C. Vogel, S. Lustigman, K. Salehi-Ashtiani, E. Ghedin · 2021 · bioRxiv
- GALECTIN-3 IN MODULATING INFLAMMATION IN ADIPOCYTES AND MACROPHAGESBraja Kishori Panigrahi, Swati Das, Faina Philberta Dumpala, Reshma Vagicharla, Sai Kumar Kunderu, Vijaya Lakshmi Bodiga · 2020 · International Journal of Advanced Research
- Dermatological Implications of Galectin-3 in Circulation: An Evaluation From the Perspective of Patients With Differential Manifestations of Post-Kala-Azar Dermal Leishmaniasis.S. Datta, M. Ghosh, Koushik Dewan, Nilotpal Banerjee, B. Saha, S. Mukhopadhyay · 2019 · American journal of dermatopathology
- IgG Antibodies to GlcNAcβ and Asialo-GM2 (GA2) Glycans as Potential Markers of Liver Damage in Chronic Hepatitis C and the Efficacy of Antiviral TreatmentE. Smorodin, B. Sergeyev, O. Kurtenkov, Tatiana Kuznetsova, J. Geller · 2018 · Disease Markers
- Mammalian Cytosolic Galectins Act as Damage-Associated Molecular Patterns, Resolution-Associated Molecular Patterns, and Pattern-Recognition Receptors in Innate ImmunitySachiko Sato · 2020 · Elsevier eBooks
- The roles of Galectin-3 in autoimmunity and tumor progressionGordana D. Radosavljevic, Vladislav Volarević, Ivan Jovanović, Marija Milovanović, Nada N. Pejnovic, Nebojša Arsenijević, Daniel K. Hsu, Miodrag L. Lukić · 2012 · Immunologic Research
- Chemical inhibition of α-mannosidase in S. mansoni schistosomula leads to reshaped N-glycosylation associated with developmental alterationsEleonore B Kuhlemaijer, Tom Veldhuizen, Quirine C. A. Hoekstra, Jinthe A. Umbach, Mathijs J. Niezen, Josephine Forde-Thomas, Gabriel Rinaldi, Karl F. Hoffmann, Angela van Diepen, Cornelis Hendrik Hokke · 2026 · Frontiers in Parasitology
- Structurally defined helminth glycan-ovalbumin conjugates reveal epitope-dependent dendritic cell uptake.Qiang Chao, Yi Jiang, Qiang Tang, Jian-Feng Zhang, Bei-Dong Wang, Chun-Rong Xiong, Bei Zhang, Song Zhao, Kun Yang · 2026 · International Journal of Biological Macromolecules
- Galectina-3 controla a proliferação intracelular de Toxoplasma gondii em células trofoblásticas humanas (linhagem BeWo)Mayara Ribeiro, Dra Eloisa Amália Vieira Ferro, Dra Celene, Maria de Oliveira Simões Alves, Celene Maria de Oliveira, Meu Irmão, F. Vocês, Conheci Te Admirei · 2020
- Les médiateurs de l'immunité anti-candida : outils d'analyse physiopathologique et intérêt diagnostiqueS. Damiens · 2012
- Generation of novel chimeric LacdiNAcS by gene fusion of α-lactalbumin and β1,4-galactosyltransferase 1S. Do · 2009 · Glycoconjugate Journal