Age-Associated Defect in Human TLR-1/2 Function

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9. Enhanced Stabilization of Atherosclerotic Plaques in Apolipoprotein E-Knockout Mice by Combinatorial Toll-like Receptor-1 and -2 Gene Silencing
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12. Immunosenescence and hurdles in the clinical management of older HIV-patients
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13. TLR4 and TLR2 activation is differentially associated with age during Parkinson’s disease
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14. Age‐Associated Inflammatory Monocytes Are Increased in Menopausal Females and Reversed by Hormone Replacement Therapy
    Roel P. H. De Maeyer, Justyna Sikora, Olivia V. Bracken, Barbara Bo-Ju Shih, Amy F. Lloyd, Hannah Peckham, Kate Hollett, K Abdelhamid, Weigang Cai, Michael James et al. · 2025 · Aging Cell
15. Metabolic reprogramming in inflammaging and aging in T cells
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19. Lateral diffusion of CD14 and TLR2 in macrophage plasma membrane assessed by raster image correlation spectroscopy and single particle tracking
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20. Immunotherapy Outcomes in Advanced Melanoma in Relation to Age
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21. Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes
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22. Sexual dimorphism in immunity and longevity among the oldest old
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23. Platelet response to influenza vaccination reflects effects of aging
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24. Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans
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25. Statistical approaches for analyzing immunologic data of repeated observations: A practical guide
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26. The Impact of Aging and Toll-like Receptor 2 Deficiency on the Clinical Outcomes of Staphylococcus aureus Bacteremia
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27. Age, serum 25-hydroxyvitamin D and vitamin D receptor (VDR) expression and function in peripheral blood mononuclear cells
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29. Metabolic dysregulation of trained immunity in immune aging and the impact of dietary patterns
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30. Innate immune response in acute critical illness: a narrative review
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32. Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood
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33. Cancer vaccination: Manipulation of immune responses at old age
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34. Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists
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35. TLR/NLRP3 inflammasome signaling pathways as a main target in frailty, cachexia and sarcopenia
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36. Effects of human Toll-like receptor 1 polymorphisms on ageing
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37. Innate Immune Responses in the Neutrophils of Community Dwelling and Nursing Home Elders
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38. Aging immunity: unraveling the complex nexus of diet, gut microbiome, and immune function
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39. Geriatric Physiology
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40. Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-Immunosuppressed Adults
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41. Roles of Toll-Like Receptors in Pathophysiology of Alzheimer’s Disease and Multiple Sclerosis
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42. Perspectives on the use and risk of adverse events associated with cytokine-storm targeting antibodies and challenges associated with development of novel monoclonal antibodies for the treatment of COVID-19 clinical cases
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43. Insights Into the Effects of Mucosal Epithelial and Innate Immune Dysfunction in Older People on Host Interactions With Streptococcus pneumoniae
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44. Less functional variants of TLR-1/-6/-10 genes are associated with age
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45. Toll Like Receptors Play a Role in General Immunity, Eye Infection and Inflammation: Tlrs for Nanodelivery
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46. Toll-Like Receptor Signaling in Alzheimer?s Disease Progression
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47. Expression of toll‐like receptor 2 mRNA in bronchial epithelial cells is not induced in RAO‐affected horses
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48. Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging
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49. Identifying Early Inflammatory Changes in Monocyte-Derived Macrophages from a Population with IQ-Discrepant Episodic Memory
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50. Mechanisms of Predisposition to Pneumonia
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51. Age‐dependent messenger RNA expression of toll‐like receptor 4 and intercellular adhesion molecule‐1 in peripheral blood mononuclear cells
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52. Principles of Geriatric Critical Care
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53. Monocyte and T Cell Immune Phenotypic Profiles Associated With Age Advancement Differ Between People With HIV, Lifestyle-Comparable Controls and Blood Donors
    Davide De Francesco, Caroline Anne Sabin, Peter Reiss, Neeltje A. Kootstra · 2020 · Frontiers in Immunology
54. Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccination
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55. Tuberculosis and COVID-19 in the elderly: factors driving a higher burden of disease
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56. Allergy and Immunology of the Aging Lung
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57. Toll-like Receptor function of murine macrophages, probed by cytokine induction, is biphasic and is not impaired globally with age
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58. At the heart of inflammation: Unravelling cardiac resident macrophage biology
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59. Rigorous antibiotic stewardship in the hospitalized elderly population: saving lives and decreasing cost of inpatient care
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60. Impact of Aging and HIV Infection on the Function of the C-Type Lectin Receptor MINCLE in Monocytes
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61. The Role of Estrogen Deficiency in Skin Aging and Wound Healing
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62. Immunity, Inflammation, and Aging
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63. Gut-Immune Interplay: Decoding the Microbiome’s Impact on Immunity and Diseases
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64. Age-Dependent Alterations in Intestinal Barrier Function: Involvement of Microbiota and TLR4 Signaling
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65. Aging in Granulomatosis with Polyangiitis and Microscopic Polyangiitis: From Pathophysiology to Clinical Management
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66. Healthy aging: when periodontal health matters
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67. Effects of aging and lifelong aerobic exercise on expression of innate immune components in skeletal muscle of women
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69. Age‐related alteration of expression and function of TLR s and NK activity in oral candidiasis
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72. Effects of Aging on Human Toll-Like Receptor Function
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