Chemotaxis of Mouse Bone Marrow Neutrophils and Dendritic Cells Is Controlled by ADP-Ribose, the Major Product Generated by the CD38 Enzyme Reaction

Cited by (146)

Items 101–146 of 146

1. Enzymology of Ca2+-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases
   Andreas H. Guse · 2023 · Cells
2. TLR2 Utilization of Borrelia Does Not Induce p38- and IFN-β Autocrine Loop-Dependent Expression of CD38, Resulting in Poor Migration and Weak IL-12 Secretion of Dendritic Cells
   Pauliina Hartiala, Jukka Hytönen, Heta Yrjänäinen, Maria Honkinen, Perttu Terho, Mirva Söderström, Markus A. Penttinen, Matti K. Viljanen · 2010 · The Journal of Immunology
3. Redox-Sensitive TRP Channels: TRPA1 and TRPM2
   Makiko Kashio, Makoto Tominaga · 2017 · InTech eBooks
4. Indolizine Derivatives Inhibit TRPM2 and Protect against Ischemic Brain Injury with an Extended Treatment Window
   Tinghao Lu, Yi Zhang, Jinbiao Li, MeiJie Dai, Huan Liu, Huajian Zhu, Shaozi Fu, Xianhao Dong, Fenghao Sun, Hongwei Lin et al. · 2025 · Journal of Medicinal Chemistry
5. Hydrolysis of the phosphoanhydride linkage of cyclic ADP‐ribose by the Mn2+‐dependent ADP‐ribose/CDP‐alcohol pyrophosphatase
   José Canales, Ascensión Fernández, Joaquim Rui Rodrigues, Rui Ferreira, João Meireles Ribeiro, Alicia Cabezas, M. Costas, José Carlos Cameselle · 2009 · FEBS Letters
6. cADPR Does Not Activate TRPM2
   Winnie Maria Riekehr, Simon Sander, Jelena Pick, Henning Tidow, Andreas Bauche, Andreas H. Guse, Ralf Fliegert · 2022 · International Journal of Molecular Sciences
7. Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype
   Joseph Antony Jude, Mythili Dileepan, Reynold A. Panettieri, Timothy Francis Walseth, Mathur Kannan · 2012 · Journal of Allergy
8. TRPM2 activation: Paradigm shifted?
   Ralf Fliegert, Hans Thomas Hölzer, Andreas H. Guse · 2018 · Cell Calcium
9. Synthesis of phosphonoacetate analogues of the second messenger adenosine 5′-diphosphate ribose (ADPR)
   Ondřej Baszczyňski, Joanna M. Watt, Monika D. Rozewitz, Ralf Fliegert, Andreas H. Guse, Barry V. L. Potter · 2020 · RSC Advances
10. TRPM2 Is Not Required for T-Cell Activation and Differentiation
    Niels Christian Lory, Mikołaj Nawrocki, Martina Corazza, Joanna Schmid, Valéa Schumacher, Tanja Bedke, Stephan Menzel, Friedrich Koch‐Nolte, Andreas H. Guse, Samuel Huber et al. · 2022 · Frontiers in Immunology
11. 2′-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca2+ concentrations
    Jelena Pick, Simon Sander, Stefanie Etzold, Anette Rosche, Henning Tidow, Andreas H. Guse, Ralf Fliegert · 2024 · Frontiers in Immunology
12. TRPs: Modulation by Drug-Like Compounds
    Michael Schaefer · 2014 · Handbook of experimental pharmacology
13. Tyrphostin AG-related compounds attenuate H 2 O 2 -induced TRPM2-dependent and -independent cellular responses
    Shinichiro Yamamoto, Takahiro Toda, Ryo Yonezawa, Takaharu Negoro, Shunichi Shimizu · 2017 · Journal of Pharmacological Sciences
14. Designer small molecules to target calcium signalling
    Joanna M. Swarbrick, Andrew M. Riley, Stephen J Mills, Barry V. L. Potter · 2015 · Biochemical Society Transactions
15. Regulating the regulators via targeting CD38 in the tumor microenvironment
    Navnita Dutta, Nabanita Halder, Eduardo N. Chini, Sungjune Kim, Alak Manna · 2026 · Frontiers in Immunology
16. Cell death induction and protection by activation of ubiquitously expressed anion/cation channels. Part 3: the roles and properties of TRPM2 and TRPM7
    Yasunobu Okada, Tomohiro Numata, Ravshan Z. Sabirov, Makiko Kashio, Petr G. Merzlyak, Kaori Sato-Numata · 2023 · Frontiers in Cell and Developmental Biology
17. Blocking Cyclic Adenosine Diphosphate Ribose-mediated Calcium Overload Attenuates Sepsis-induced Acute Lung Injury in Rats
    Qianyi Peng, Yu Zou, Lina Zhang, Meilin Ai, Wei Liu, Yuhang Ai · 2016 · Chinese Medical Journal
18. Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9
    Ellen Gattkowski, Trevor J. Rutherford, Franziska Möckl, Andreas Bauche, Simon Sander, Ralf Fliegert, Henning Tidow · 2021 · FEBS Journal
19. Second messenger analogues highlight unexpected substrate sensitivity of CD38: total synthesis of the hybrid “L-cyclic inosine 5′-diphosphate ribose”
    Joanna M. Watt, Richard Milton Graeff, MARK P. THOMAS, Barry V. L. Potter · 2017 · Scientific Reports
20. Pathophysiological significance of the TRPM2 ion channel as a potential target in cancer, neurological disorders, and ischemia/reperfusion injury
    Sara Sultana, Yang Xie, Muhaymin Kamal, Wei LI · 2026 · Pharmacological Research
21. Evolutionary trajectory of TRPM2 channel activation by adenosine diphosphate ribose and calcium
    Cheng Ma, Yanping Luo, Congyi Zhang, Cheng Cheng, Ning Hua, Xiaocao Liu, Jianan Wu, Luying Qin, Peilin Yu, Jianhong Luo et al. · 2024 · 中国科学通报：英文版
22. Evolving understandings for the roles of CD38 protein in autoimmunity and autoimmune disease
    Xiaochun Ye, Jieying Zhang, Mengping Song, Ping Wang, Irma Arés, Bernardo López-Torres, Marta Martínez, María‐Rosa Martínez‐Larrañaga, Jorge-Enrique Maximiliano, Arturo Anadón et al. · 2026 · Clinical & Experimental Immunology
23. Regulation of Murine Dendritic Cell Functions by Calcium Channels
    Adriana Sumoza‐Toledo · 2014 · SOJ Immunology
24. TRPM2 is a direct pain transducer
    Linda Varghese, Mujahid Alizada, Jinquan Yang, Feng Ye, Xiaoqiu Yuan, Mitali Malhotra, Xuming Zhang · 2026 · Proceedings of the National Academy of Sciences
25. Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity elicited in these mice
    Paula Carrillo-Rodríguez, José-Ángel Robles-Guirado, Adrián Cruz-Palomares, Miguel Ángel Palacios-Pedrero, Elena González-Paredes, Alex Mas-Ciurana, Carolina Franco-Herrera, Paloma A. Ruiz-de-Castroviejo-Teba, Antonio Lario, Victoria Longobardo et al. · 2022 · Frontiers in Immunology
26. CD38
    Leopoldo Santos‐Argumedo · 2017 · Springer eBooks
27. Changes in the Phenotype and Metabolism of Peritoneal Macrophages in Mucin-2 Knockout Mice and Partial Restoration of Their Functions In Vitro After L-Fucose Treatment
    Elena L. Arzhanova, Yulia Makusheva, Elena G. Pershina, Snezhanna S. Medvedeva, Ekaterina A. Litvinova · 2024 · International Journal of Molecular Sciences
28. Neuroimmune Regulation by TRPM2 Channels
    Xuming Zhang, Mitali Malhotra · 2026 · Cells
29. Alterations in TRPM2 and TRPM7 Functions in the Immune System Could Confer Susceptibility to Neurodegeneration
    Meredith C. Hermosura · 2013 · Springer eBooks
30. Identification of N-formylated Peptides with Neutrophilic Chemotactic Activity in Mycobacterium tuberculosis
    Kristin Dean, Bock‐Gie Jung, Jôsimar Dornelas Moreira, Buka Samten · 2022 · Zoonoses
31. Identification and characterization of novel ADP-ribosyl cyclase family members
    Renee Marie Hirte · 2011 · University of Minnesota Digital Conservancy (University of Minnesota)
32. Themed Section: Cytoskeleton, Extracellular Matrix, Cell Migration, Wound Healing and Related Topics
    Sujitra Detchokul, AG Frauman · 2014 · British Journal of Pharmacology
33. Artemisinin inhibits innate immune cell chemotaxis, cytokine production and NET release
    Hassan O. J. Morad, Suaib Luqman, Larissa Garcia Pinto, Kevin Peter Cunningham, Bruno Vilar, Georgia Clayton, Manu Shankar‐Hari, Peter Anthony McNaughton · 2022 · Research Square
34. Faculty Opinions recommendation of Pharmacological Activation of Estrogen Receptor Beta Augments Innate Immunity to Suppress Cancer Metastasis.
    Adeboyega Oyelere · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
35. CD38
    Leopoldo Santos‐Argumedo · 2016 · Springer eBooks
36. Effect L-fucose on the metabolism of peritoneal macrophages of Muc2 −/− mice in vitro
    Elena L. Arzhanova, Yulia Makusheva, Elena G. Pershina, Snezhanna S. Medvedeva, Ekaterina A. Litvinova · 2023 · Research Square
37. Advances in the development of transient receptor potential melastatin 2 channel inhibitors
    Shiyao Chen, Yanping LUO, Peilin Yu, Xiaomin Yue, Wei Yang · 2025 · Journal of Zhejiang University (Medical Sciences)
38. Non-invasive approach for endoluminal biopsy coupled with single-cell proteomics allows for immune characterization of intracranial aneurysms
    Joseph Paul Antonios, Batur Gültekin, Brianna Carusillo Theriault, Kanat Yalcin, Danielle F. Miyagishima, Nana Adenu‐Mensah, Nanthiya Sujijantarat, Andrew B. Koo, Joseph O Haynes, Paul Anthony Cedeño et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
39. Inherited retinal degenerations: PARP regulates calpain activation via TRPM2 channels in rd1 mouse photoreceptors
    Jie Yan, Lei Kong, Zhijian Zhao, Qianlu Yang, Lan Wang, Qianxi Yang, Christian Harteneck, Kangwei Jiao, Zhulin Hu, François Paquet‐Durand · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
40. Poly(ADP-ribose) polymerase regulates transient receptor potential channel M2-dependent calpain activation in rd1 mouse retinal degeneration
    Jie Yan, Lei Kong, Zhijian Zhao, Qianlu Yang, Lan Wang, Qianxi Yang, Christian Harteneck, Kangwei Jiao, zhulin Hu, François Paquet‐Durand · 2026 · Neural Regeneration Research
41. Impact of CD38 Deficiency on B Cell Development in CD19 ‐Deficient Mice
    A. Abrego‐Peredo, Carlos Arturo Gallardo-Hernández, Gabriela López‐Herrera, Héctor Romero‐Ramírez, F. García‐García, B. Pineda‐Olvera, Juan Carlos Rodríguez‐Alba · 2026 · Scandinavian Journal of Immunology
42. CD38 in hepatic pathobiology: mechanisms, disease association and therapeutic implications
    Jason W.‐L. Eng, Blake R. Peterson, Sylvester Black · 2026 · Annals of Hepatology
43. BindingDB Entry 50033542: Flavonoids as inhibitors of human CD38.
    BindingDB · 2012 · UC San Diego
44. BindingDB Entry 50001835: Design, synthesis and biological activities of 2,3-dihydroquinazolin-4(1H)-one derivatives as TRPM2 inhibitors.
    BindingDB · 2020 · UC San Diego
45. BindingDB Entry 50043805: Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists.
    BindingDB · 2014 · UC San Diego
46. BindingDB Entry 50023246: Indolizine Derivatives Inhibit TRPM2 and Protect against Ischemic Brain Injury with an Extended Treatment Window.
    BindingDB · 2026 · UC San Diego