NFATc1 Regulates PD-1 Expression upon T Cell Activation

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   Ying L. Liu, Cecilie Liv Bager, Nicholas Willumsen, Divya Ramchandani, Naomi Kornhauser, Ling Lu, Marta Vallee Cobham, Eleni Andreopoulou, Tessa Cigler, Anne L. Moore et al. · 2021 · npj Breast Cancer
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   Rui Liu, Huifang Li, Shu Li · 2024 · Cell Insight
3. Concurrent, but not sequential, PD-1 blockade with a DNA vaccine elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer
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4. Counter-regulation of rejection activity against human liver grafts by donor PD-L1 and recipient PD-1 interaction
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    Xinbing Sui, Junhong Ma, Weidong Han, Xian Wang, Yong Fang, Da Li, Hongming Pan, Li Zhang · 2015 · Oncotarget
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    Yi Xia, Leonard Jeffrey Medeiros, Ken H. Young · 2015 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
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    Marco Cardone, Karla Y. Garcia, Mulualem E. Tilahun, Lisa F. Boyd, Sintayehu Gebreyohannes, Masahide Yano, Gregory Roderiquez, Adovi D. Akue, Leslie Juengst, Elliot Mattson et al. · 2018 · Journal of Clinical Investigation
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    Caterina Ieranò, Dario Righelli, Crescenzo D’Alterio, Maria Napolitano, Luigi Portella, Giuseppina Rea, Federica Auletta, Sara Santagata, Anna Maria Trotta, Giuseppe Guardascione et al. · 2022 · Journal for ImmunoTherapy of Cancer
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    Xuechen Yin, Lingfeng He, Zhigang Guo · 2023 · Immunology
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    Mengjun Zhong, Rili Gao, Ruocong Zhao, Youxue Huang, Cunte Chen, Kehan Li, Xibao Yu, Dingrui Nie, Zheng Chen, Xin Liu et al. · 2022 · Cell Death and Disease
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    Sicong Ma, Roger Sandhoff, Xiu Luo, Fuwei Shang, Qiaozhen Shi, Zhaolong Li, Jingxia Wu, Yanan Ming, Frank Schwarz, Alaa Madi et al. · 2024 · Science Immunology
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    Hao Hu, Pavel N. Zakharov, Orion J. Peterson, Emil R. Unanue · 2020 · Proceedings of the National Academy of Sciences
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    Krzysztof Giannopoulos · 2019 · Journal of Clinical Medicine
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    Lisanne Heim, Juliane Friedrich, Marina Engelhardt, Denis Iulian Trufa, Carol Imanuel Geppert, Ralf J. Rieker, Horia Sı̂rbu, Susetta Finotto · 2018 · Cancer Research
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    Li, Chunyang, Li, Weiyun, Xiao, Jun, Jiao, Shaozhuo, Teng, Fei, Xue, Shengjie, Zhang, Chi, Sheng, Chun, Leng, Qibin, Rudd, Christopher E et al. · 2015 · EMBO Molecular Medicine
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    Marilena Letizia, Yin‐Hu Wang, Ulrike Kaufmann, Lorenz Gerbeth, A Sand, Max Brunkhorst, Patrick Weidner, J Ziegler, Chotima Böttcher, Stephan Schlickeiser et al. · 2022 · EMBO Molecular Medicine
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    Patrick J. Shaw, Carl Weidinger, Martin Vaeth, Kevin Luethy, Susan M. Kaech, Stefan Feske · 2014 · Journal of Clinical Investigation
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    Shixiang Bao, Xiaopei Jiang, Shuai Jin, Peipei Tu, Jingtao Lu · 2021 · Frontiers in Oncology
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    Ji Zha, Annalise R. Smith, Samita S. Andreansky, Valerie C. Bracchi-Ricard, John R. Bethea · 2014 · Journal of Neuroinflammation
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    Nikolaos Patsoukis, Jessica D. Weaver, Laura Strauss, Christoph Herbel, Pankaj Seth, Vassiliki A. Boussiotis · 2017 · Frontiers in Immunology
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    Shigenori Nagai, Miyuki Azuma · 2019 · Advances in experimental medicine and biology
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    Jill Angelosanto, E. John Wherry · 2010 · Immunological Reviews
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    Jiu-cheng Zhang, Weidong Chen, Jean Bustamante Alvarez, Kelly Qi Jia, Lei Shi, Qiang Wang, Ning Zou, Kai He, Hua Zhu C · 2018 · Acta Pharmacologica Sinica
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    Louise M. C. Webb, Michelle A. Linterman · 2017 · Immunology
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    Dipankar Nandi, Sanmoy Pathak, Taru Verma, Madhulika Singh, Avik Chattopadhyay, Samriddhi Thakur, Abinaya Raghavan, Abhijeet Gokhroo, Vijayamahantesh Vijayamahantesh · 2020 · Journal of Biosciences
45. Immune checkpoint blockade: Releasing the brake towards hematological malignancies
    Yi Xia, Leonard Jeffrey Medeiros, Ken H. Young · 2015 · Blood Reviews
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    Junjie Zhang, Hao Feng, Jun Zhao, Emily R. Feldman, Si–Yi Chen, Weiming Yuan, Canhua Huang, Omid Akbari, Scott A. Tibbetts, Pinghui Feng · 2016 · Cell Reports
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    Anandaroop Mukhopadhyay, Jocelyn H. Wright, Shawna A. Shirley, David A. Canton, Christoph Burkart, Richard J. Connolly, Jean S. Campbell, Robert Hamilton Pierce · 2018 · Gene Therapy
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    Georgi Vasilev, Mariana G. Ivanova, Ekaterina Ivanova‐Todorova, Kalina D. Tumangelova-Yuzeir, Ekaterina Krasimirova, Rumen Malinov Stoilov, Dobroslav Stanimirov Kyurkchiev · 2019 · Rheumatology International
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    Shima Bastaki, Mahzad Irandoust, Armin Ahmadi, Mohammad Hojjat‐Farsangi, Patrick Ambrose, Shahin Hallaj, Mahdi Edalati, Ghasem Ghalamfarsa, Gholamreza Azizi, Mehdi Yousefi et al. · 2020 · Life Sciences
50. Programmed Cell Death 1-Directed Immunotherapy for Enhancing T-Cell Function
    Koichi Araki, Ben Youngblood, Rafi Ahmed · 2013 · Cold Spring Harbor Symposia on Quantitative Biology
51. The Short Isoform of the CEACAM1 Receptor in Intestinal T Cells Regulates Mucosal Immunity and Homeostasis via Tfh Cell Induction
    Lanfen Chen, Zhangguo Chen, Kristi Baker, Elizabeth M. Halvorsen, Andre Pires da Cunha, Magdalena B. Flak, Georg Kurt Gerber, Yu-Hwa Huang, Shuhei Hosomi, Janelle C. Arthur et al. · 2012 · Immunity
52. Programmed Cell Death 1-Directed Immunotherapy for Enhancing T-Cell Function
    Koichi Araki, Ben Youngblood, Rafi Ahmed · 2013 · Cold Spring Harbor Symposia on Quantitative Biology
53. TGF-β1 induces PD-1 expression in macrophages through SMAD3/STAT3 cooperative signaling in chronic inflammation
    Zhigang Lei, Rui Tang, Wu Yu, Chenxu Mao, Weijie Xue, Junyao Shen, Jiaojiao Yu, Xiaohong Wang, Xin Qi, Chuan Wei et al. · 2024 · JCI Insight
54. Renal transplantation in patients with HIV
    Lynda Ann Frassetto, Clara Tan-Tam, Peter G. Stock · 2009 · Nature Reviews Nephrology
55. Glucocorticoids potentiate the inhibitory capacity of programmed cell death 1 by up-regulating its expression on T cells
    Natsumi Maeda, Takumi Maruhashi, Daisuke Sugiura, Kenji Shimizu, Il‐mi Okazaki, Taku Okazaki · 2019 · Journal of Biological Chemistry
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    Łukasz Wojciech, Chin Wen Png, Eileen Yiling Koh, Dorinda Yan Qin Kioh, Lei Deng, Ziteng Wang, Liangzhe Wu, Maryam Hamidinia, Desmond W. H. Tung, Wei Zhang et al. · 2023 · The EMBO Journal
57. Transcriptional and epigenetic regulation of T cell hyporesponsiveness
    Renata M. Pereira, Patrick G. Hogan, Anjana Rao, Gustavo Martínez · 2017 · Journal of Leukocyte Biology
58. Regulation of PD-1 in T cells for cancer immunotherapy
    Xibao Yu, Rili Gao, Yangqiu Li, Chengwu Zeng · 2020 · European Journal of Pharmacology
59. Reversing T-cell exhaustion in immunotherapy: a review on current approaches and limitations
    Yasser Tabana, Tae Chul Moon, Arno G. Siraki, Shokrollah Elahi, Khaled Barakat · 2021 · Expert Opinion on Therapeutic Targets
60. Myeloid-Derived Suppressor Cells Impair Alveolar Macrophages through PD-1 Receptor Ligation during Pneumocystis Pneumonia
    Guang-Sheng Lei, Chen Zhang, Chao‐Hung Lee · 2014 · Infection and Immunity
61. The role of PD‐1 in regulation of macrophage apoptosis and its subversion by Leishmania donovani
    Shalini Roy, Purnima Gupta, Shreyasi Palit, Moumita Basu, Anindita Ukil, Pijush K. Das · 2017 · Clinical & Translational Immunology
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    Paola Fisicaro, Carolina Boni, Valeria Barili, Diletta Laccabue, Carlo I. Ferrari · 2018 · Current Opinion in Virology
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    Karlhans Fru Che, Esaki Muthu Shankar, Sundaram Muthu, Sasan Zandi, Mikael Sigvardsson, Jorma Hinkula, Davorka Messmer, Marie Larsson · 2012 · Molecular Medicine
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    Koichi Araki, Shivaprakash Gangappa, Dirck L. Dillehay, Barry T. Rouse, Christian P. Larsen, Rafi Ahmed · 2010 · The Journal of Experimental Medicine
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    Edwina Naik, Vishva M. Dixit · 2016 · The Journal of Immunology
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    Thomas Hans Fehr, Carrie L. Lucas, Josef M. Kurtz, Takashi Onoe, Guiling Zhao, Timothy Hogan, Casey Vallot, Anjana Rao, Megan Sykes · 2009 · Blood
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    Bara Sarraj, Junsheng Ye, Ahmed Ibrahim Akl, Guodong Chen, Jiao-Jing Wang, Zheng Zhang, Farida Abadja, Michael M. Abecassis, Stephen D. Miller, Geoffrey S. Kansas et al. · 2014 · Proceedings of the National Academy of Sciences
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    Jia‐Zhu Wu, Xiaojing Xu, Eun-Joon Lee, Austin Young Shull, Lirong Pei, Farrukh Tauseef Awan, Xiaoling Wang, Jeong-Hyeon Choi, Libin Deng, Hong‐Bo Xin et al. · 2016 · Oncotarget
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    Yongxiang Yang, Yuqin Ye, Chen Chen, Chuiguang Kong, Xinhong Su, Xin Zhang, Wei Bai, Xiaosheng He · 2019 · NeuroImmunoModulation
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    Kar Muthumani, Devon J. Shedlock, Daniel K. Choo, Paolo Fagone, Omkar Uday Kawalekar, Jonathan Goodman, Chaoran B. Bian, Aarti A. Ramanathan, Parikh Atman, Pablo Tebas et al. · 2011 · The Journal of Immunology
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    Youliang Zhao, Yaqian Qu, Changfu Hao, Wu Yao · 2023 · Frontiers in Immunology
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    Zhitao Li, Guoqiang Sun, Guangshun Sun, Ye Cheng, Liangliang Wu, Qian Wang, Chengyu Lv, Yichan Zhou, Yongxiang Xia, Weiwei Tang · 2021 · Frontiers in Oncology
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    Alexander P. R. Bally, Dennis Kyle Neeld, Peiyuan Lu, Parimal Majumder, Yan Tang, Benjamin G. Barwick, Qing Wang, Jeremy M. Boss · 2019 · The Journal of Immunology
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    Shengwen Shang, Yongjie Zhao, Kaiqiang Qian, Yuexuan Qin, Xinyi Zhang, Tianyue Li, Lidong Shan, Meili Wei, Jun Xi, Bikui Tang · 2022 · Biomedicine & Pharmacotherapy
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    Bingyu Wang, Zaibo Zhang, Wenbo Liu, Bibo Tan · 2022 · Biomedicine & Pharmacotherapy
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    Laura S. van Dam, Verena de Zwart, Friederike A. G. Meyer‐Wentrup · 2014 · Pediatric Blood & Cancer
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    Matthew R. Farren, Rebecca C. Hennessey, Reena Shakya, Omar Elnaggar, Gregory S. Young, Kari Lynn Kendra, Yosef Landesman, Sivan Elloul, Marsha L. Crochiere, Boris Klebanov et al. · 2017 · Molecular Cancer Therapeutics
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    Christopher Tucker, Jason S. Mitchell, Tijana Martinov, Brandon J. Burbach, Lalit K. Beura, Joseph C Wilson, Alexander J. Dwyer, Lovejot M. Singh, Matthew F. Mescher, Brian T. Fife · 2020 · The Journal of Immunology
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    Christopher Tay, Yamin Qian, Shimon Sakaguchi · 2020 · Cancers
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    Sanne H. Tonino, Pablo J. van de Berg, Sandro L. Yong, Ineke J. M. ten Berge, Marie José Kersten, René A. W. van Lier, Marinus H. J. van Oers, Arnon Philip Kater · 2012 · Leukemia & lymphoma/Leukemia and lymphoma
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     Cecilia M. Fernandez-Ponce, Margarita Dominguez‐Villar, Enrique Aguado, Francisco Jose Garcia-Cozar · 2014 · PLoS ONE