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Cited by 189

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Dengue Virus Identification by the Plaque Reduction Neutralization Test

Russell, Philip K, Nisalak, Ananda·1967·The Journal of Immunology

Abstract

Summary: A method for identification and serologic classification of dengue viruses using a plaque reduction neutralization test and monkey immune serum is described. Results of typing 40 strains confirm the usefulness of this method for classification of low passage strains. Adaptation of the isolates to suckling mice or tissue culture was not required and strains within each of the four dengue serotypes were readily identified. Cross neutralization tests using monkey antiserum confirmed the results of the one-way neutralization test using antiserum to reference dengue strains and also indicated antigenic variation within serotypes 1, 2 and 4.

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Metadata

Authors
Russell, P. K., & Nisalak, A.
Venue
The Journal of Immunology
Published
1967-08-01
Volume
99
Issue
2
Pages
291-296
ISSN
  • 0022-1767 (ISSN-L)
  • 1550-6606
OpenAlex
W1521072280
Cited by
189
References
0
FWCI
6.02
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Dengue Virus Identification by the Plaque Reduction Neutralization Test. https://app.cochat.ai/papers/10.4049/jimmunol.99.2.291
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Russell, P. K., & Nisalak, A. (1967). Dengue Virus Identification by the Plaque Reduction Neutralization Test. The Journal of Immunology. https://doi.org/10.4049/jimmunol.99.2.291

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.