Thyrotoxic periodic paralysis
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TPP occurs predominantly in men, with a male-to-female ratio of approximately 20:1.
“Despite a higher incidence of thyrotoxicosis in women, TPP occurs predominantly in men, with a male-to-female ratio of approximately 20:1 [2]”
From Iatrogenic Thyrotoxicosis and Corticosteroid-Triggered Hypokalemic Periodic Paralysis in a Patient With Treated Hypothyroidism (2026) · cites this paper as [2]
Reported precipitating factors of TPP include high carbohydrate ingestion, strenuous exercise, trauma, acute upper respiratory tract infection, high-salt diet, emotional stress, exposure to cold, alcohol ingestion, menstruation, and use of drugs such as corticosteroids, epinephrine, acetazolamide, and non-steroidal anti-inflammatory drugs.
“The precipitating factors of TPP reported in the literature included high carbohydrate ingestion, strenuous exercise, trauma, acute upper respiratory tract infection (URI), high-salt diet, emotional stress, exposure to cold, alcohol ingestion, menstruation, and use of drugs such as corticosteroids, epinephrine, acetazolamide, and non-steroidal anti-inflammatory drugs (2, 3, 14, 22, 23, 24).”
From A 10-year analysis of thyrotoxic periodic paralysis in 135 patients: focus on symptomatology and precipitants (2013) · cites this paper as [3]
TPP has the highest prevalence in Asian populations.
“and the highest prevalence of cases occurring in Asian populations [2].”
From Iatrogenic Thyrotoxicosis and Corticosteroid-Triggered Hypokalemic Periodic Paralysis in a Patient With Treated Hypothyroidism (2026) · cites this paper as [2]
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References 54 · Cited by 254
- Authors
- Lin, S.-H.
- Affiliations
- Tri-Service General Hospital (TW)
- Corresponding author
- Lin, Shih-Hua
- ORCID
- Lin, Shih-Hua
- Venue
- Mayo Clinic Proceedings
- Publisher
- Elsevier BV
- Published
- 2005-01
- Volume
- 80
- Issue
- 1
- Pages
- 99-105
- ISSN
- 0025-6196 (ISSN-L)
- OpenAlex
- W2016313902
- Cited by
- 254
- References
- 54
- Citations by year
- 2026: 13 · 2025: 17 · 2024: 9 · 2023: 12 · 2022: 13 · 2021: 13 · 2020: 10 · 2019: 5 · 2018: 5 · 2017: 9 · 2016: 10 · 2015: 10 · 2014: 19 · 2013: 13 · 2012: 16
- FWCI
- 1.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mayo Clinic Proceedings (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Potassium and Related Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- thyrotoxic periodic paralysis, hyperthyroidism, hypokalemia, muscle weakness, hypophosphatemia, hypercalciuria, potassium chloride supplementation, beta-blockers, electrocardiographic findings, electromyography
- MeSH terms
- Calcium, Humans, Phosphates, Thyrotoxicosis, Hypokalemic Periodic Paralysis
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