Factors associated with health-related quality of life in adults with asthma. A cross-sectional study
Open accessAbstract
Background: The measurement of health-related quality of life (HRQoL) is increasingly recognized as an important endpoint, as a reflection of the effects of the disease from a patient perspective. Our aim was to evaluate the factors determining the HRQoL in patients with asthma, according to the EQ-5D questionnaire. Methods: Patients were included using multi-stage sampling, from Primary Care clinics from all the Autonomous Communities in Spain. The patients included were: over 18 years-old, with a confirmed diagnosis of asthma for at least one year, and had visited a Health Centre in the previous 2 years. The characteristics of the asthma disease, the adherence to treatment, the socio-demographic variables, the smoking habits, and the asthma control were collected using a questionnaire. The influence of the different variables included in the study on the EQ-5D was evaluated using multivariate logistic regression analysis. Results: A total of 2,125 patients were finally included (57.7% females, mean age 48 years). The response rate was 95.4%. Some factors showed a considerable detrimental effect on the HRQoL of asthmatics. Advanced age, lower educational level and poor control of asthma are significantly associated with a worse quality of life in all the dimensions assessed by the EQ-5D scale. The baseline severity of the asthma, and having been admitted to hospital are related to a worse quality of life in 5 of the 6 dimensions analyzed. Conclusion: In our study, we could identify some factors related to quality of life in asthma patients. The most important were advanced age, lower education level, and poor control of the asthma.
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References 36 · Cited by 8
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- Authors
- Gonzalez-Barcala, F.-J., De la Fuente-Cid, R., Tafalla, M., Nuevo, J., & Caamaño-Isorna, F.
- Affiliations
- AstraZeneca (Spain) (ES)
- Corresponding author
- Tafalla, Mónica
- Nuevo, Javier
- Venue
- Multidisciplinary Respiratory Medicine
- Publisher
- Mattioli1885
- Published
- 2012-10-02
- Volume
- 7
- ISSN
- 1828-695X (ISSN-L)
- 2049-6958
- OpenAlex
- W4230064681
- Cited by
- 8
- References
- 36
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2019: 2 · 2015: 1
- FWCI
- 0.21
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Multidisciplinary Respiratory Medicine (publishedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- asthma, health-related quality of life, EQ-5D, asthma control, medication adherence, smoking, educational attainment, age, hospitalization, asthma severity, primary care patients
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