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Cited by 247Mental Health Treatment and AccessTreatment of Major DepressionOpioid Use Disorder Treatment

The DOI matches its Crossref record, with a small difference in title or year.

National Trends in Long-Term Use of Antidepressant Medications: Results From the US National Health and Nutrition Examination Survey

Mojtabai, Ramin, Olfson, Mark·2014·The Journal of Clinical Psychiatry
DOI 10.4088/jcp.13m08443
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Abstract

Article AbstractObjective: To assess the trend in long-term use of antidepressants by persons aged ≥ 18 years, and the correlates of such use, in the United States from 1999 to 2010. Method: We examined trends in duration of antidepressant use and correlates of long-term use in data from 6 waves of the cross-sectional National Health and Nutrition Examination Survey (N = 35,379), a representative survey of the general population. Results: The overall prevalence of antidepressant use increased from 6.5% in 1999-2000 to 10.4% in 2009-2010 (odds ratio = 1.54; 95% CI, 1.31-1.81; P < .001). This included an increase from 3.0% to 6.9% in long-term use (≥ 24 months; OR = 2.12; 95% CI, 1.75-2.57; P < .001). Medium-term (6 to < 24 months; from 1.3% to 1.6%) and short-term use (< 6 months; from 2.2% to 1.8%) of antidepressants did not change appreciably in this period. The increasing trend in long-term antidepressant use was limited to adults who received their care from general medical providers (adjusted OR = 3.86; 95% CI, 2.57-5.80; P < .001). Conclusions: From 1999 to 2010, there was a marked increase in long-term use of antidepressant medications in the United States, explaining the overall increasing trend in antidepressant use. This trend calls for greater vigilance in prescribing antidepressants for long periods of time. J Clin Psychiatry © Copyright 2013 Physicians Postgraduate Press, Inc. Submitted: February 26, 2013; accepted July 9, 2013. Online ahead of print: December 10, 2013 (doi:10.4088/JCP.13m08443). Corresponding author: Ramin Mojtabai, MD, PhD, MPH, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, 624 N Broadway, Hampton House/Room 797, Baltimore, MD 21205 (rmojtaba@jhsph.edu).

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Metadata

Authors
Mojtabai, R., & Olfson, M.
Affiliations
  • Johns Hopkins University (US)
  • Columbia University (US)
Corresponding author
Mojtabai, Ramin
ORCID
Venue
The Journal of Clinical Psychiatry
Publisher
Physicians Postgraduate Press, Inc
Published
2013-12-10
Volume
75
Issue
02
Pages
169-177
ISSN
0160-6689 (ISSN-L)
DOI
10.4088/jcp.13m08443
OpenAlex
W2075265772
Cited by
247
References
0
Citations by year
2026: 10 · 2025: 16 · 2024: 27 · 2023: 16 · 2022: 22 · 2021: 18 · 2020: 28 · 2019: 21 · 2018: 17 · 2017: 26 · 2016: 22 · 2015: 13 · 2014: 11
FWCI
22.95
Type
journal article
Language
en
Open access
closed
Locations
  • The Journal of Clinical Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
U.S. Public Health Service (NCT01528839.)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Keywords
antidepressant use, long-term antidepressant use, antidepressant prescribing trends, depression, general medical care, prescribing patterns, United States adults, NHANES, mental health service utilization, insurance status
MeSH terms
Adult, Aged, Antidepressive Agents, Cross-Sectional Studies, Drug Utilization, Female, Humans, Male, Middle Aged, Nutrition Surveys, Drug Prescriptions, Time Factors, United States, Prevalence, Young Adult

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