Chronic Vagus Nerve Stimulation Significantly Improves Quality of Life in Treatment-Resistant Major Depression

Conway, Charles R.; Kumar, Arun; Xiong, Willa; Bunker, Mark; Aaronson, Scott T.; Rush, A. John

doi:10.4088/jcp.18m12178

Chronic Vagus Nerve Stimulation Significantly Improves Quality of Life in Treatment-Resistant Major Depression

OBJECTIVE To compare quality-of-life (QOL) change associated with treatment as usual (TAU, any antidepressant treatment) versus adjunctive vagus nerve stimulation treatment (VNS + TAU) in a population of patients with treatment-resistant depression (TRD) for 5 years. METHODS Self-reported QOL ass…