Sepsis associated with Lactobacillus bacteremia in a patient with ischemic colitis
Open accessAbstract
Lactobacillus species is a known commensal of the mouth, gastrointestinal, and genitourinary tract. However, its isolation on blood cultures is often overlooked and attributed to bench contamination. We present a case of a 58-year-old immunocompetent male who initially presented with altered mental status, but developed sepsis from Lactobacillus bacteremia during his hospital course, while on mechanical ventilation. He was found to have ischemic colitis on colonoscopy. His condition improved with antibiotics and supportive management. Using this example of ischemic colitis, we stress that in the right clinical setting, Lactobacillus bacteremia is a harbinger for a serious underlying pathology and should not be ignored.
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Our review revealed 49 case reports of LB without any history of probiotic use.
“Our review also revealed 49 case reports of LB without any history of probiotic use (Table 1) [24,26,27,33,35,45,46,47,48,49,50,51].”
From Lactobacillus Bacteremia and Probiotics: A Review (2023) · cites this paper as [35]
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Probiotic supplements might not be universally-effective and safe: A review
Kothari, D., Patel, S., & Kim, S.-K. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.12.104 · Cited by 445 · see citing works
Lactobacillus Bacteremia and Probiotics: A Review
Kullar, R., Goldstein, E. J. C., Johnson, S., & McFarland, L. V. (2023) · Microorganisms · doi:10.3390/microorganisms11040896 · Cited by 156 · see citing works
“LB has been reported in patients with cancer [10,31–33], ischemic or ulcerative colitis [34,35], that are immunocompromised (HIV, chronic steroids, chemotherapy, or transplant patients) [36–38], or in preterm neonates with underlying conditions (short bowel syndrome, growth restriction) [39].”
BackgroundMeini, S., Laureano, R., Fani, L., Tascini, C., Galano, A., Antonelli, A., & Rossolini, G. M. (2015) · Infection · doi:10.1007/s15010-015-0798-2 · Cited by 106 · see citing works
- Authors
- Kulkarni, H. S., & Khoury, C. C.
- Affiliations
- Washington University in St. Louis (US)
- University of Pittsburgh Medical Center (US)
- Corresponding author
- Kulkarni, Hrishikesh S.
- Venue
- Indian Journal of Critical Care Medicine
- Publisher
- Jaypee Brothers Medical Publishing
- Published
- 2014
- Volume
- 18
- Issue
- 9
- Pages
- 606-608
- ISSN
- 0972-5229 (ISSN-L)
- 1998-359X
- PMC
- PMC4166876
- OpenAlex
- W1988647977
- Cited by
- 19
- References
- 1
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 4 · 2015: 1
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Indian Journal of Critical Care Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Infections and bacterial resistance
- Keywords
- sepsis, ischemic colitis, blood culture contamination, mechanical ventilation, immunocompetent patient, altered mental status, antibiotic therapy
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