Determinants of compliance to iron supplementation among pregnant women in Enugu, Southeastern Nigeria
Open accessAbstract
BACKGROUND: Anemia in pregnancy is highly prevalent among antenatal clinic attendees in Enugu, Nigeria despite the practice of routine iron supplementation in pregnancy. The major problem with iron supplementation in pregnancy is compliance, and this may be a potential driver to the persistent high prevalence of anemia in this population. OBJECTIVES: To find out the compliance rate and determinants of compliance to iron supplementation among pregnant women in Enugu, southeastern Nigeria. MATERIALS AND METHODS: This was a questionnaire-based cross-sectional study of eligible pregnant women receiving antenatal care at the University of Nigeria Teaching Hospital (UNTH), Ituku/Ozalla, Enugu, Nigeria between April 1, 2012 and January 31, 2013. RESULTS: The knowledge of iron supplementation was 76.3% ( n = 302), however, the compliance rate was 65.9% ( n = 261). Tertiary level of education and high social class were factors significantly associated with compliance to iron supplementation after adjusting for other factors in the binary logistic regression analysis ( P < 0.05). The major barriers to compliance to iron supplementation included gastrointestinal side effects of iron supplements (41.7%), non-affordability of iron supplements (28.3%), and forgetfulness (15.0%) among the antenatal mothers. CONCLUSION: The compliance rate of 65.9% for iron supplementation by pregnant mothers in Enugu can further be improved by providing the drug free of charge in the short term and improvement in education and socioeconomic class of the populace in the long run.
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Studies conducted in Nigeria, India, and Nepal support the association between not facing problems in health institution during supplement collection and adherence.
“The finding is supported by studies conducted in Nigeria, India and Nepal [31–33].”
From Magnitude and factors associated with adherence to Iron and folic acid supplementation among pregnant women in Aykel town, Northwest Ethiopia (2019) · cites this paper as [31]
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Compliance to iron supplementation during pregnancy
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Arega Sadore, A., Abebe Gebretsadik, L., & Aman Hussen, M. (2015) · Journal of Environmental and Public Health · doi:10.1155/2015/781973 · Cited by 114 · see citing works
Sendeku, F. W., Azeze, G. G., & Fenta, S. L. (2020) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-020-2835-0 · Cited by 108 · see citing works
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Determinants of Iron Consumption among Pregnant Women in Southern Senegal
Niang, K., Faye, A., Diégane Tine, J. A., Diongue, F. B., Ndiaye, B., Ndiaye, M. B., Ndiaye, P., & Tal-Dia, A. (2017) · Open Journal of Obstetrics and Gynecology · doi:10.4236/ojog.2017.71005 · Cited by 32 · see citing works
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- Authors
- Ugwu, E., Olibe, A., Obi, S., & Ugwu, A.
- Affiliations
- University of Nigeria Teaching Hospital (NG)
- Venue
- Nigerian Journal of Clinical Practice
- Published
- 2014
- Volume
- 17
- Issue
- 5
- Pages
- 608
- ISSN
- 1119-3077 (ISSN-L)
- OpenAlex
- W1983017412
- Cited by
- 114
- References
- 1
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 6 · 2023: 13 · 2022: 30 · 2021: 9 · 2020: 15 · 2019: 11 · 2018: 3 · 2017: 3 · 2016: 8 · 2015: 3
- FWCI
- 4.39
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Nigerian Journal of Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Public Health and Nutrition
- Keywords
- iron supplementation, medication adherence, pregnant women, anemia in pregnancy, prenatal care, determinants of compliance, gastrointestinal adverse effects, socioeconomic status, educational attainment, Enugu
- MeSH terms
- Adult, Anemia, Cross-Sectional Studies, Female, Humans, Health Knowledge, Attitudes, Practice, Middle Aged, Nigeria, Patient Compliance, Pregnancy, Pregnancy Complications, Hematologic, Prenatal Care, Iron, Dietary, Dietary Supplements, Young Adult
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