Swallow syncope: Clinical presentation, diagnostic criteria, and therapeutic options
Open accessAbstract
We recently encountered three patients with episodes of syncope associated with food ingestion. A 31-year-old woman had an episode of syncope in the hospital while drinking soda. Transient asystole was noted on the telemonitor, confirming the diagnosis of swallow syncope. The other two patients were 78- and 80 year old gentlemen, respectively, who presented with recurrent and transient episodes of dizziness during deglutition. Extensive work-up of syncope was negative in both cases and a diagnosis of swallow syncope was made by clinical criteria. These cases illustrate the challenging problem of swallow syncope. The diagnosis can be suspected on the basis of clinical presentation and confirmed with the demonstration of transient brady-arrhythmia during deglutition. Medical management includes avoiding trigger foods, use of anticholinergics, and/or placement of a permanent cardiac pacemaker.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Evidence for treatment of situational syncope is limited mainly to case reports, small case series, and small observational studies.
“Evidence for treatment is limited mainly to case reports, small case series, and small observational studies (431,433–436).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [435]
The Discussion (page not supplied) says fewer than 100 cases of swallow syncope had been published, and the paper presents three treated cases. This supports a limited, case-based treatment literature for swallow syncope, but it does not establish the claimed mix of small case series and observational studies or extend that assessment to situational syncope generally. (LLM, conf=0.83)
Experimental — accuracy not yet measuredEvidence for treatment of situational syncope is limited mainly to case reports, small case series, and small observational studies.
“Evidence for treatment is limited mainly to case reports, small case series, and small observational studies (280,282–285).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary (2017) · cites this paper as [284]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Postprandial Hypotension: Epidemiology, Pathophysiology, and Clinical Management
Jansen, R. W. M. M., & Lipsitz, L. A. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-122-4-199502150-00009 · Cited by 406 · see citing works
The sinus nerve and baroreceptor input to the medulla of the cat.
Lipski, J., McAllen, R. M., & Spyer, K. M. (1975) · The Journal of Physiology · doi:10.1113/jphysiol.1975.sp011081 · Cited by 142 · see citing works
Glossopharyngeal neuralgia: neurosurgical treatment and differential diagnosis
Teixeira, M. J., de Siqueira, S. R. D. T., & Bor‐Seng‐Shu, E. (2008) · Acta Neurochirurgica · doi:10.1007/s00701-007-1493-6 · Cited by 70 · see citing works
Swallow Syncope, a Case Report and Review of the Literature
Omi, W., Murata, Y., Yaegashi, T., Inomata, J.-I., Fujioka, M., & Muramoto, S. (2005) · Cardiology · doi:10.1159/000089543 · Cited by 65 · see citing works
Daccarett, M., Jetter, T. L., Wasmund, S. L., Brignole, M., & Hamdan, M. H. (2011) · Europace · doi:10.1093/europace/eur201 · Cited by 58 · see citing works
Swallow Syncope: A Case Report and Review of the Literature
Mitra, S., Ludka, T., Rezkalla, S. H., et al. (2011) · Clinical Medicine & Research · doi:10.3121/cmr.2010.969 · Cited by 49 · see citing works
Effects of caffeine on heart rate and QT variability during sleep
Bonnet, M. H., Tancer, M. E., Uhde, T. W., & Yeragani, V. K. (2005) · Depression and Anxiety · doi:10.1002/da.20127 · Cited by 46 · see citing works
Caffeine attenuates vasovagal reactions in female first-time blood donors.
Sauer, L. A., & France, C. R. (1999) · Health Psychology · doi:10.1037//0278-6133.18.4.403 · Cited by 46 · see citing works
CARDIAC SYNCOPE AFTER SWALLOWING
James, A. (1958) · The Lancet · doi:10.1016/s0140-6736(58)91578-2 · Cited by 46 · see citing works
Carcinoma of the oesophagus with "swallow syncope".
TOMLINSON, I. W., & Fox, K. M. (1975) · BMJ · doi:10.1136/bmj.2.5966.315 · Cited by 38 · see citing works
Nakagawa, S., Hisanaga, S., Kondoh, H., et al. (1987) · Journal of Electrocardiology · doi:10.1016/0022-0736(87)90010-0 · Cited by 34 · see citing works
Lipsitz, L. A., Jansen, R. W. M. M., Connelly, C. M., et al. (1994) · Clinical Science · doi:10.1042/cs0870259 · Cited by 34 · see citing works
Atrioventricular block produced by swallowing, with documentation by His bundle recordings
Lichstein, E., & Chadda, K. D. (1972) · The American Journal of Cardiology · doi:10.1016/0002-9149(72)90450-x · Cited by 32 · see citing works
Wik, B., & Hillestad, L. (1975) · BMJ · doi:10.1136/bmj.3.5986.747 · Cited by 29 · see citing works
Swallowing syncope: Observations in the absence of conduction system or esophageal disease
Kadish, A. H., Wechsler, L., & Marchlinski, F. E. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90418-3 · Cited by 26 · see citing works
Deglutition syncope and atrioventricular block selectively induced by hot food and liquid
Kunis, R. L., Garfein, O. B., Pepe, A. J., et al. (1985) · The American Journal of Cardiology · doi:10.1016/0002-9149(85)90274-7 · Cited by 20 · see citing works
Swallow syncope after aneurysmectomy of the thoracic aorta
Nakano, T., Okano, H., Konishi, T., et al. (1987) · Heart and Vessels · doi:10.1007/bf02073646 · Cited by 16 · see citing works
Letter: Carcinoma of the oesophagus with "swallow syncope".
Waddington, J. K. B., Matthews, H. R., Evans, C. C., et al. (1975) · BMJ · doi:10.1136/bmj.3.5977.232-a · Cited by 14 · see citing works
Armstrong, P. W., McMillan, D. G., & Simon, J. B. (1985) · PubMed · Cited by 13 · see citing works
Woody, R. C., & Kiel, E. A. (1986) · PEDIATRICS · doi:10.1542/peds.78.3.507 · Cited by 11 · see citing works
Supraventricular Tachycardia Induced by Swallowing
Ho, K. L., Beshir, M. A., El-Zimaity, H. M. T., et al. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-157-7-201210020-00020 · Cited by 6 · see citing works
Foreman, J. R., Vigh, A., & Wardrop, R. M. (2011) · The American Journal of Medicine · doi:10.1016/j.amjmed.2010.10.009 · Cited by 4 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [12]Kopald HH Roth HP Fleshler B Pritchard WH Vagovagal syncope; report of a case associated with diffuse esophageal spasm N Engl J Med 1964 271 1238 41 14234269
Cited by
Sorted by citations
2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.03.004 · Cited by 484 · see citing works
2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.003 · Cited by 327 · see citing works
Shen, W.-K., Sheldon, R. S., Benditt, D. G., Cohen, M. I., Forman, D. E., Goldberger, Z. D., Grubb, B. P., Hamdan, M. H., Krahn, A. D., Link, M. S., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.03.002 · Cited by 155 · see citing works
- Authors
- Girotra, M., Garg, S., Glasser, S., & Dutta, S.
- Affiliations
- Johns Hopkins University (US)
- Sinai Hospital (US)
- Corresponding author
- Girotra, Mohit
- Venue
- Saudi Journal of Gastroenterology
- Published
- 2014
- Volume
- 20
- Issue
- 4
- Pages
- 207
- ISSN
- 1319-3767 (ISSN-L)
- PMC
- PMC4131302
- OpenAlex
- W2009096679
- Cited by
- 24
- References
- 22
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2022: 1 · 2021: 3 · 2019: 2 · 2018: 1 · 2017: 9 · 2015: 2 · 2014: 2
- FWCI
- 4.29
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Saudi Journal of Gastroenterology (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Health Professions › Speech and Hearing › Dysphagia Assessment and Management
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- syncope, food ingestion, swallowing, anticholinergic agents, cardiac pacemaker, dietary triggers, elderly patients, dizziness
- MeSH terms
- Adult, Aged, Aged, 80 and over, Deglutition, Electrocardiography, Female, Humans, Male, Syncope, Endoscopy, Digestive System
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review