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Cited by 19Viral Infections and Immunology ResearchNeurogenetic and Muscular Disorders ResearchPeripheral Neuropathies and Disorders

Postpolio syndrome: a review of lived experiences of patients

Open access
Olunu, Esther, Fakoya, AdegbenroOmotuyi, Oluwasanmi, OluwaseyiJacob, Mckenzie, DevaunnaAndrene, Adewole, IdowuOluwasegun, Aluka, ChristianO, Iyasse, James·2019·International Journal of Applied and Basic Medical Research
DOI 10.4103/ijabmr.ijabmr_333_18PMC PMC6652271
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Abstract

Postpolio syndrome (PPS) refers to a group of conditions that are present in patients, years after recovery from initial acute paralytic poliomyelitis. About 15%-80% of 20 million polio survivors worldwide will experience exacerbation of symptoms which typically appear 15-30 years after the resolution of initial poliomyelitis. Symptoms include new muscle weakness, fatigue, myalgia, joint pain, dysphagia, and difficulty breathing. Other reported symptoms include cold intolerance, sleep disorder, dysphonia, loss of stamina, musculoskeletal deformities, cardiovascular disorders, psychosocial problems, and restless legs syndrome. These symptoms are attributed to the superimposed neuronal loss of aging with inflammatory mechanisms, but without any convincing evidence of viral reactivation. Risk factors include female gender, respiratory symptoms, normal aging, permanent disability caused by motor neuron damage, muscle overuse and disuse, aging, and immunologic mechanisms. Hypothyroidism-induced myopathy and fibromyalgia are a differential diagnosis for PPS, and exclusion diagnosis is required as confirmatory criteria for PPS. The symptoms of PPS presented determine the course of management.

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  • Bulbar dysfunction and dysphagia have been described in post-polio syndromes, where chronic neuromuscular weakness and impaired coordination can compromise safe swallowing and nutrition.

    “Bulbar dysfunction and dysphagia have also been described in post-polio syndromes, where chronic neuromuscular weakness and impaired coordination can compromise safe swallowing and nutrition (Kay et al., 2018; Oluwasanmi et al., 2019).”

    From Autonomic nervous system and gastrointestinal manifestations with an emphasis on gastric dysfunction (2026) · cites this paper as Oluwasanmi et al., 2019

    The Clinical Manifestations > Dysphagia section links bulbar-muscle involvement to swallowing difficulty, aspiration risk, and nutritional problems. Management of Postpolio Syndrome also says laryngeal and esophageal muscle weakness can cause dysphagia. The copy does not specifically identify impaired coordination as a contributing mechanism; page numbers were not provided. (LLM, conf=0.86)

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References 48 · Cited by 19

Research works printed but not linked: 43

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Authors
Olunu, E., Fakoya, A., Oluwasanmi, O., Mckenzie, D., Adewole, I., Aluka, C., & Iyasse, J.
Affiliations
  • All Saints University School of Medicine (DM)
  • University of Medicine and Health Sciences (KN)
Venue
International Journal of Applied and Basic Medical Research
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2019
Volume
9
Issue
3
Pages
129
ISSN
2229-516X (ISSN-L)
DOI
10.4103/ijabmr.ijabmr_333_18
PMC
PMC6652271
OpenAlex
W2959089085
Cited by
19
References
48
Citations by year
2026: 4 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 3
FWCI
1.27
Type
journal article
Language
en
Open access
Licence
cc-by-nc-sa
Locations
  • International Journal of Applied and Basic Medical Research (publishedVersion)
  • PubMed Central (publishedVersion, cc-by-nc-sa)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Viral Infections and Immunology Research
  • Health Sciences › Medicine › Genetics › Neurogenetic and Muscular Disorders Research
  • Health Sciences › Medicine › Neurology › Peripheral Neuropathies and Disorders
Keywords
post-polio syndrome, polio survivors, lived experience, muscle weakness, fatigue, dysphagia, restless legs syndrome, diagnosis of exclusion, aging, motor neuron damage, risk factors, symptom management

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