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Why provide 40 sessions of hyperbaric oxygen therapy to patients with traumatic brain injury?
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“Vascular remodeling, angiogenesis, and neurogenesis require sustained stimulation, and studies suggest that at least 40–60 sessions are needed to initiate and consolidate neurovascular integration (24).”
From Hyperbaric oxygen therapy improves post-concussion symptoms in adults with childhood traumatic brain injury: a retrospective cohort study (2025) · cites this paper as [24]
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Research works printed but not linked: 11
- Mitchell, 2022, Decompression sickness and arterial gas embolism, N Engl J Med, 386, 1254, 10.1056/NEJMra2116554 · DOI
- Weaver, 2018, Hyperbaric oxygen for post-concussive symptoms in United States military service members: a randomized clinical trial, Undersea Hyperb Med, 45, 129, 10.22462/03.04.2018.1 · DOI
- Eve, 2016, Hyperbaric oxygen therapy as a potential treatment for post-traumatic stress disorder associated with traumatic brain injury, Neuropsychiatr Dis Treat, 12, 2689, 10.2147/NDT.S110126 · DOI
- Hadanny, 2022, Hyperbaric oxygen therapy in children with post-concussion syndrome improves cognitive and behavioral function: a randomized controlled trial, Sci Rep, 12, 15233, 10.1038/s41598-022-19395-y · DOI · Paper page
- Miller, 2015, Effects of hyperbaric oxygen on symptoms and quality of life among service members with persistent postconcussion symptoms: a randomized clinical trial, JAMA Intern Med, 175, 43, 10.1001/jamainternmed.2014.5479 · DOI
- Harch, 2020, Hyperbaric oxygen therapy for mild traumatic brain injury persistent postconcussion syndrome: a randomized controlled trial, Med Gas Res, 10, 8, 10.4103/2045-9912.279978 · DOI
- Doenyas-Barak, 2023, The use of hyperbaric oxygen for veterans with PTSD: basic physiology and current available clinical data, Front Neurosci, 17, 1259473, 10.3389/fnins.2023.1259473 · DOI
- Wälchli, 2023, Shaping the brain vasculature in development and disease in the single-cell era, Nat Rev Neurosci, 24, 271, 10.1038/s41583-023-00684-y · DOI
- Paredes, 2018, Neurovascular communication during CNS development, Dev Cell, 45, 10, 10.1016/j.devcel.2018.01.023 · DOI
- Tal, 2015, Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury, Restor Neurol Neurosci, 33, 943
- Ablin, 2023, Hyperbaric oxygen therapy compared to pharmacological intervention in fibromyalgia patients following traumatic brain injury: a randomized, controlled trial, PLoS One, 18, e0282406, 10.1371/journal.pone.0282406 · DOI · Paper page
Cited by
Shabi Shlifer, A., Suzin, G., Shorer, R., Lang, E., Finci, S., Elman-Shina, K., Doenyas-Barak, K., & Efrati, S. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1641033 · Cited by 2
Metadata
- Authors
- Borlongan, C. V., & Hadanny, A.
- Affiliations
- Department of Neurosurgery and Brain Repair, Center of Excellence for Aging and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, FL, USA
- Aviv Clinics, The Villages, FL, USA; Sagol Center for Hyperbaric Medicine and Research, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel; School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
- ORCID
- Borlongan, Cesar V.
- Venue
- Medical Gas Research
- Published
- 2024-09-25
- Volume
- 15
- Issue
- 1
- Pages
- 132-133
- ISSN
- 2045-9912
- Cited by
- 9
- References
- 0
- Language
- en
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- CoChat. (2026). Citation check: Why provide 40 sessions of hyperbaric oxygen therapy to patients with traumatic brain injury? https://app.cochat.ai/papers/10.4103/mgr.medgasres-d-24-00029
- The paper
- Borlongan, C. V., & Hadanny, A. (2025). Why provide 40 sessions of hyperbaric oxygen therapy to patients with traumatic brain injury? Medical Gas Research. https://doi.org/10.4103/mgr.medgasres-d-24-00029
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.