The DOI matches its Crossref record.
Tissue distribution of bovine viral diarrhea virus antigens in persistently infected cattle
Open accessAbstract
The tissue distribution and cellular localization of viral antigens in three cattle with persistent bovine viral diarrhea virus (BVDV) infection was studied. In three cases, necropsy findings of oral ulcers, abmasal ulcers and necrosis of Peyer's patches were suspected have been caused by BVDV infection. Non-cytopathic BVDV was isolated from a tissue pool of liver, kidneys and spleen. Immunohistochemical detection of BVDV showed that BVDV antigens were detected in both epithelial and nonepithelial cells in all examined organs, including the gastrointestinal tract, liver, pancreas, lung, lymphatic organs (spleen, lymph nodes), adrenal gland, ovary, uterus, and the mammary gland. These findings support the hypothesis that animals with persistent BVDV infection spread BVDV through all routes, and that infertility in BVDV infection is associated with the infection of BVDV in the ovaries and uteri.
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“Meanwhile, BVDV antigens were frequently found in the respiratory tracts of animals with BRD [131].”
From Strategies for Bovine Respiratory Disease (BRD) Diagnosis and Prognosis: A Comprehensive Overview (2024) · cites this paper as [131]
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Strategies for Bovine Respiratory Disease (BRD) Diagnosis and Prognosis: A Comprehensive Overview
Kamel, M. S., Davidson, J. L., & Verma, M. S. (2024) · Animals · doi:10.3390/ani14040627 · Cited by 76
“Meanwhile, BVDV antigens were frequently found in the respiratory tracts of animals with BRD [131].”
Background
Metadata
- Authors
- Shin, T., & Acland, H.
- Affiliations
- Jeju National University (KR)
- ORCID
- Shin, Taekyun
- Venue
- Journal of Veterinary Science
- Published
- 2001
- Volume
- 2
- Issue
- 2
- Pages
- 81
- ISSN
- 1229-845X (ISSN-L)
- OpenAlex
- W2399756918
- Cited by
- 40
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2022: 1 · 2021: 2 · 2020: 3 · 2018: 1 · 2017: 2 · 2016: 2 · 2014: 4 · 2013: 1 · 2012: 3
- FWCI
- 0.60
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Journal of Veterinary Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Disease Management and Epidemiology
- Health Sciences › Medicine › Infectious Diseases › Viral gastroenteritis research and epidemiology
- Keywords
- bovine viral diarrhea virus, persistent infection, subcellular localization, oral ulcers, abomasal ulcers, infertility, ovarian infection, uterine infection
- MeSH terms
- Adrenal Glands, Animals, Antigens, Viral, Diarrhea Viruses, Bovine Viral, Bovine Virus Diarrhea-Mucosal Disease, Cattle, Digestive System, Female, Immunohistochemistry, Infertility, Female, Kidney, Lung, Lymphatic System, Mammary Glands, Animal, Ovary, Uterus
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- CoChat. (2026). Citation check: Tissue distribution of bovine viral diarrhea virus antigens in persistently infected cattle. https://app.cochat.ai/papers/10.4142/jvs.2001.2.2.81
- The paper
- Shin, T., & Acland, H. (2001). Tissue distribution of bovine viral diarrhea virus antigens in persistently infected cattle. Journal of Veterinary Science. https://doi.org/10.4142/jvs.2001.2.2.81
