Identifying risk factors for severe hypoglycemia in hospitalized patients with diabetes
Abstract
Objective Some of the deleterious effects of hypoglycemia in hospitalized patients include increased rates of mortality and longer length of stay. Our primary objective was to identify the risk factors associated with severe hypoglycemia to identify those patients at highest risk. Methods The medical records of 5,026 patients with diabetes mellitus (DM) admitted in 2010 were reviewed to identify those patients that developed severe hypoglycemia (blood glucose [BG] Results Out of 5,026 DM patients included in our review, 81 experienced severe hypoglycemia (1.6%). Statistically higher proportions of chronic kidney disease (CKD; 69.1% vs. 46.9%, P Conclusion Prior episodes of hypoglycemia in the hospital, the presence of type 1 DM, insulin use, and sepsis were identified as independent risk factors for the development of severe hypoglycemia in the hospital.
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In a study of hospitalized individuals, 84% of people who had an episode of severe hypoglycemia (defined as <40 mg/dL) had a preceding episode of hypoglycemia (<70 mg/dL) during the same admission.
“In a study of hospitalized individuals, 84% of people who had an episode of severe hypoglycemia (defined as <40 mg/dL [<2.2 mmol/L]) had a preceding episode of hypoglycemia (<70 mg/dL [<3.9 mmol/L]) during the same admission (110).”
From 16. Diabetes Care in the Hospital: Standards of Care in Diabetes—2026 (2026) · cites this paper as [110]
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References 24 · Cited by 41
- Authors
- Dendy, J. A., Chockalingam, V., Tirumalasetty, N. N., Dornelles, A., Blonde, L., Bolton, P. M., Meadows, R. Y., & Andrews, S. S.
- Affiliations
- Ochsner Medical Center (US)
- Corresponding author
- Dendy, Jared A.
- Venue
- Endocrine Practice
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 20
- Issue
- 10
- Pages
- 1051-1056
- ISSN
- 1530-891X (ISSN-L)
- OpenAlex
- W2048693825
- Cited by
- 41
- References
- 24
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 5 · 2023: 3 · 2022: 2 · 2021: 1 · 2020: 5 · 2019: 3 · 2018: 3 · 2017: 6 · 2016: 4 · 2015: 2 · 2014: 2
- FWCI
- 3.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Endocrine Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Health Professions › Emergency Medical Services › Patient Safety and Medication Errors
- Keywords
- severe hypoglycemia, diabetes mellitus, hospitalized patients, risk factors, insulin use, type 1 diabetes, sepsis, chronic kidney disease, congestive heart failure, liver cirrhosis, blood glucose, length of hospital stay, mortality, risk stratification, hospital costs, quality of care, patient safety, quality of life
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