Using the “reverse Warburg effect” to identify high-risk breast cancer patients: Stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers

Witkiewicz, Agnieszka K., Whitaker-Menezes, Diana, Dasgupta, Abhijit, Philp, Nancy J., Lin, Zhao, Gandara, Ricardo, Sneddon, Sharon, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.·2012·Cell Cycle

Cited by (241)

Items 201–241 of 241

  1. Cancer-Associated Fibroblasts: Heterogeneity and Bimodality in Oncogenesis
    Nataliya A. Lunina, Dina R. Safina, Sergey V. Kostrov · 2023 · Molecular Biology
  2. Metabolic coupling in phyllodes tumor of the breast and its association with tumor progression
    Nah Ihm Kim, Min Sik Park, Sun‐Seog Kweon, Ji Lee · 2023 · Oncology Letters
  3. The role of hexokinase in cancer
    Paulina Stachyra, Paweł Cisek, Michał Janiszewski, Ludmiła Grzybowska‐Szatkowska · 2020 · Postępy Higieny i Medycyny Doświadczalnej
  4. Metabolic Imbalance Associated Mitophagy in Tumor Cells: Genesis and Implications
    Madhuri Chaurasia, Shashank Misra, Anant Narayan Bhatt, Asmita Das, Bilikere Srinivasa Rao Dwarakanath, Kulbhushan Sharma · 2015 · Journal of cancer research updates
  5. Milking the stroma in triple-negative breast cancer
    Alastair Mark Thompson, T. J. Newman · 2012 · Cell Cycle
  6. MONOCARBOXYLIC ACID TRANSPORTERS
    Marilyn E. Morris, Nisha V. Kwatra · 2022 · Wiley eBooks
  7. Glycolytic cancer-associated fibroblasts orchestrate metabolic remodeling in the tumor microenvironment
    Xinyu Cui, Akshaya Poonepalle, Chloe Shay, Yong Teng · 2026 · Journal of Experimental & Clinical Cancer Research
  8. Experimental Study of Warburg Effect in Keloid Nodules: Implication for Downregulation of miR-133b
    Yuumi Lee, Yuko Ito, Kohei Taniguchi, Takashi Nuri, Sang‐Woong Lee, Koichi Ueda · 2023 · Plastic & Reconstructive Surgery Global Open
  9. Cancer-Associated Fibroblasts: Heterogeneity and Bimodality in Oncogenesis
    Nataliya A. Lunina, Dina R. Safina, Sergey V. Kostrov · 2023 · Molecular Biology
  10. Nanomaterial-Mediated Targeting of Mitochondrial Metabolism: Strategies and Applications in Cancer Therapy
    Yue Hu, Peichen Xie, Jialin Li, Rui Liu, Haotong Wang, Zhicheng Wang, Chunyan Liu · 2026 · International Journal of Nanomedicine
  11. Expression of Reactive Oxygen Species-Related Proteins according to Androgen and HER-2 Status in Estrogen Receptor-Negative Breast Cancer
    Ji‐Ye Kim, Woo Hee Jung, Ja Seung Koo · 2014 · Pathobiology
  12. ‘The charmingest place’: non-coding RNA, lineage tracing, tumor heterogeneity, metastasis and metabolism - new methods in mammary gland development and cancer: the fifth ENBDC Workshop
    Robert B. Clarke, Julia Stingl, María dM Vivanco, Mohamed Bentires‐Alj · 2013 · Breast Cancer Research
  13. Mitochondrial Genome Changes as Cancer Biomarkers in Circulation
    Gabriel D. Dakubo · 2016 · Springer eBooks
  14. Baisse du citrate dans la cellule tumorale : une jauge à remettre à niveau ?
    Philippe Icard, T. Vallantin, Perrine Kafara, Jean‐Marc Steyaert, Laurent H. Schwartz, Hubert Lincet · 2015 · ONCOLOGIE
  15. Implications from a microarray analysis: Solute carrier proteins may be potential targets to combat stemness of breast cancer
    Meltem Demirel Kars · 2020 · Hacettepe Journal of Biology and Chemistry
  16. Cancer Metabolism and Aggressive Tumor Behavior
    Sanjib Chaudhary, Ashu Shah, Ramesh Pothuraju, Imayavaramban Lakshmanan, Apar Kishor Ganti, Surinder K. Batra · 2022 · Springer eBooks
  17. CRYO-EM AND SLC TRANSPORTERS
    Joshua A. Lees, Seungil Han · 2022 · Medicinal chemistry reviews
  18. Understanding the Metabolic Cross Talk Between Cancer Cells and Cancer-Associated Fibroblasts
    Anthony Michael Alvarado, Levi Arnold, Sufi Mary Thomas · 2020 · Springer eBooks
  19. Tumor-stroma relationships
    Richard F. Wooster · 2012 · Cell Cycle
  20. Exploring the role of LDH in cancer cells through the use of small-molecule inhibitors.
    Lorenza Di Ianni · 2018 · AMS Dottorato Institutional Doctoral Theses Repository (University of Bologna)
  21. NOVEL THERAPEUTIC TARGETS IDENTIFIED BY HIGH-THROUGHPUT TECHNOLOGIES FOR TRIPLE-NEGATIVE BREAST CANCER
    Christine Y. Shiang · 2013 · Digital Commons-TMC (Texas Medical Center)
  22. Is the Small Size of a Breast Cancer Tumor the Crucial Point for Successful Medical Treatment?
    Marie Strunová, David Pavlista, J Kobilková, Jiřı́ Pokorný, M Janoušek, Lenka Bauerová, A Jandová · 2014 · Prague Medical Report
  23. Einfluss des Transkriptionsfaktors Nuclear factor E2-related factor 2 (Nrf2) auf die Metabolische Reprogrammierung kolorektaler Zellen während der entzündlichen Karzinogenese des Darmes
    K Diehl, I Bauer, M Witt-Ramdohr, Florian Deisinger, Susanne Sebens, H. Schäfer · 2015 · Zeitschrift für Gastroenterologie
  24. Uusi suundi kasvajate energiametabolismi uuringutes
    Tuuli Käämbre, Andre Koit, Igor N. Shevchuk, Vladimir Tšekulajev, Kersti Tepp, Natalja Timohhina, Jelena Bogovskaja, Vahur Valvere, Valdur A. Saks · 2014 · Ajakirjad. Journals by UT
  25. The Prognostic Implications of FIX and FLO Patterns in Mucinous Colon Carcinomas
    Sülen Sarıoğlu, Güray Aktürk, Selman Sökmen, Hülya Ellıdokuz, Aras Emre Canda, Mehtat Ünlü, Abdullah Haluk Sirin, Özgül Sağol, Cem Terzi, Mehmet Füzün · 2018 · Journal of Gastrointestinal Cancer
  26. Stromal lactic acid transporter : MCT4 expression as an indicator of prognosis in papillary thyroid cancer
    임승혁 · 2018 · YUHSpace (Yonsei University Medical Library)
  27. Exercício físico aeróbico de intensidade moderada reduz a velocidade de crescimento e modula o metabolismo energético tumoral em modelo experimental de câncer de mama triplo-negativo
    Anderson Vulczak · 2019 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  28. JAMMIT Analysis Defines 2 Semi-Independent Immune Processes Common to 29 Solid Tumors
    Emory Zitello, Michael Vo, Shaoqiu Chen, Scott A. Bowler, Vedbar S. Khadka, Thomas Wenska, Peter R. Hoffmann, Gordon Okimoto, Youping Deng · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  29. Pathological biomarkers predict recurrence and metastasis in patients with lacrimal gland adenoid cystic carcinoma
    Xiaowen Zhou, Yiyi Feng, Yidi Yang, Shuai Li, Chunyan Zong, Yilin Yu, Tianyu Zhu, Jiahao Shi, Renbing Jia, Xianqun Fan et al. · 2023 · Research Square
  30. Relationship of Transforming Growth Factor-Βeta, C-Reactive Protein, and Lactate Dehydrogenase in Bronchial Washing with the Diagnosis of Non-Small Cell Carcinoma Lung Cancer
    Putu Kessi Vikaneswari, Ni Wayan Candrawati, Ida Ayu Jasminarti Dwi Kusumawardani, Ni Luh Putu Eka Arisanti, I Desak Putu Agung Krisdanti, Gede Oky Aryanthana, Pande Made Budi Wadanta, Ida Bagus Ngurah Rai · 2023 · International Journal Of Scientific Advances
  31. Exercise and Energy Metabolism in Cancer Research
    Anderson Vulczak, Luciane C. Alberici · 2024 · Interdisciplinary cancer research
  32. Additional file 1 of Shikonin blocks CAF-induced TNBC metastasis by suppressing mitochondrial biogenesis through GSK-3β/NEDD4-1 mediated phosphorylation-dependent degradation of PGC-1α
    Fan, Shuangqin, Yan, Xiaomin, Xiaoxia Hu, Liu, Xing, Shijie Zhao, Zhang, Yue, Xiaofeng Zhou, Shen, Xiangchun, Qi Qi, Yan Chen · 2024 · Figshare
  33. Acides aminés et cancer : LAT1, un transporteur essentiel à l’activité mTORC1 et la croissance tumorale
    Yann Cormerais · 2016 · theses.fr (ABES)
  34. Association Between SUVmax and Tumour-Stroma Ratio in Breast Cancer: A Pathological Correlation Study
    Fatma Esra Ateş Kahya, Mehmet Onur Kahya, Feray Aras, Devrim Önder, Ayça Tan, Gül Gümüşer · 2026 · Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi
  35. The Dynamic Alliance of p53 and Metabolism in the Tumor Microenvironment Shapes Tumor Evolution
    Sebastien M. Joruiz, Francesco Napoletano, Rebecca Bertolio, Giannino Del Sal · 2026 · BioEssays
  36. Monocarboxylate transporters in physiology and cancer: from fundamentals to clinical translation
    Julieta Afonso, Joana Pereira-Vieira, Vera Miranda‐Gonçalves, Sara Granja, Celine Marques Pinheiro, Fátima Baltazar · 2026 · Physiological Reviews
  37. Therapeutic Redox Reprogramming in Breast Cancer: From Antioxidant Modulation to Precision Nanomedicine
    Nina Kummer, Sabina Gayibova, Takhir Aripov, Désirée Gül, Mustafa Dolaz, Burcu Önal Acet, Leyla Polat Köse, Mehmet Odabaşı, Roland H. Stauber, Ömür Acet · 2026 · Antioxidants
  38. Monocarboxylate transporters 1 and 4 in tumor lactate exchange: Molecular mechanisms, pharmacological inhibition, and therapeutic translation
    Xinyu Chen, Jiajie Lu, Yu Chen, Xinqun Liu, 吴群煌, Ruyi Jin, Hui Guo, Qiao Zhang, Peng Zhao, Yuwei Wang · 2026 · Biochemical Pharmacology
  39. Synthesis and Biological Evaluation of 5‐Arylpyrazoles as Potential MCT 1 Inhibitors Targeting Lactate Transport
    Irina P. Fonareva, E. V. Svirshchevskaya, Еlena V. Mitroshina, Ekaterina A. Marasanova, Maria V. Vedunova, Elena A. Zaburdaeva, Alexey Yu. Fedorov, Ekaterina S. Shchegravina · 2026 · ChemMedChem
  40. BindingDB Entry 50046028: Monocarboxylate transporter 1 inhibitors as potential anticancer agents.
    BindingDB · 2016 · UC San Diego
  41. BindingDB Entry 50047606: Coumarin carboxylic acids as monocarboxylate transporter 1 inhibitors: In vitro and in vivo studies as potential anticancer agents.
    BindingDB · 2017 · UC San Diego