CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis
Capparelli, Claudia, Chiavarina, Barbara, Whitaker-Menezes, Diana, Pestell, Timothy G., Pestell, Richard G., Hulit, James, Andò, Sebastiano, Howell, Anthony +3 more·2012·Cell Cycle
DOI 10.4161/cc.21884
Cited by (226)
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- Additional file 1 of Mesenchymal stem cells lose the senescent phenotype under 3D cultivationOlga A. Krasnova, Kovaleva, A., Saveleva, A., Kulakova, K., Olga A. Bystrova, Martynova, M., Domnina, A., Sopova, J., Irina E. Neganova · 2024 · Figshare
- Additional file 7 of An integrated autophagy-related gene signature predicts prognosis in human endometrial CancerJun Zhang, Wang, Ziwei, Zhao, Rong, An, Lanfen, Xing Zhou, Zhao, Yingchao, Wang, Hongbo · 2020 · Figshare
- Additional file 5 of Mesenchymal stem cells lose the senescent phenotype under 3D cultivationOlga A. Krasnova, Kovaleva, A., Saveleva, A., Kulakova, K., Olga A. Bystrova, Martynova, M., Domnina, A., Sopova, J., Irina E. Neganova · 2024 · Figshare
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- Characterization of the Signaling Pathways Involved in Cellular Cannibalism Elicited by Ionizing RadiationDorine de Jong · 2018 · theses.fr (ABES)
- Caractérisation du rôle de la voie de réponse aux dommages à l'ADN et des lysosomes dans la mort cellulaire et la sénescence induites par un ligand G-quadruplexeJennifer Beauvarlet · 2018 · theses.fr (ABES)
- Rôle des vésicules extracellulaires endothéliales dans la propagation de signaux pro-sénescents et thrombo-inflammationRonald Saraswat · 2023 · theses.fr (ABES)
- Orchestration of Autophagy and Senescence: Kinases Take the Center StageAlakananda Basu · 2026 · Cells
- Tumor cells escape from therapy-induced senescence: from molecular mechanisms to targeted interventionYu Han, Lie Ma, Xiangyu Ma · 2026 · Biology Direct
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- Cellular senescence and regulated cell death in cancer: mechanisms, cross-regulatory networks and therapeutic implicationsLinna Du, Yueyue Zhang, Ruohan Liang, Bin Song, Jun Zhou, 夏贤武, Chibo Liu, Kongming Wu, Xuan Cao · 2026 · Journal of Hematology & Oncology