The Down syndrome-related protein kinase DYRK1A phosphorylates p27Kip1and Cyclin D1 and induces cell cycle exit and neuronal differentiation

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Items 101–194 of 194

1. B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation
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2. G1 Dynamics at the Crossroads of Pluripotency and Cancer
   Dalia Fleifel, Jeanette Gowen Cook · 2023 · Cancers
3. Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
   Huang‐Ju Tu, Min‐Wu Chao, Chien‐Chung Lee, Chao-Shiang Peng, Yiwen Wu, Tony Eight Lin, Yu-Wei Chang, Shih‐Chung Yen, Kai‐Cheng Hsu, Shiow‐Lin Pan et al. · 2024 · Journal of Enzyme Inhibition and Medicinal Chemistry
4. Molecular targets and therapeutic strategies for triple-negative breast cancer
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5. 5-Methoxybenzothiophene-2-Carboxamides as Inhibitors of Clk1/4: Optimization of Selectivity and Cellular Potency
   Ahmed K. ElHady, Dalia S. El‐Gamil, Po‐Jen Chen, Tsong‐Long Hwang, Alireza Abadi, Mohammad Abdel‐Halim, Matthias Engel · 2021 · Molecules
6. Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model
   Hawley, Laura E., Stringer, Megan, Deal, Abigail J., Folz, Andrew, Goodlett, Charles R., Roper, Randall J. · 2024 · Neurobiology of Disease
7. A novel inhibitor rescues cerebellar defects in a zebrafish model of Down syndrome–associated kinase Dyrk1A overexpression
   Astrid Buchberger, Lena Schepergerdes, Maren Flaßhoff, Conrad Kunick, Reinhard Wolfgang Köster · 2021 · Journal of Biological Chemistry
8. Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases
   Youssef Aboushady, Moustafa Tarek Gabr, Ahmed K. ElHady, Mohamed Salah, Alireza Abadi, Gerrit Wilms, Walter B. Becker, Mohammad Abdel‐Halim, Matthias Engel · 2021 · ACS Chemical Neuroscience
9. Development of novel conformationally restricted selective Clk1/4 inhibitors through creating an intramolecular hydrogen bond involving an imide linker
   Dalia S. El‐Gamil, Ahmed K. ElHady, Po‐Jen Chen, Tsong‐Long Hwang, Alireza Abadi, Mohammad Abdel‐Halim, Matthias Engel · 2022 · European Journal of Medicinal Chemistry
10. Disease Modeling of Rare Neurological Disorders in Zebrafish
    Myeongjoo Son, Dae Yu Kim, Cheol‐Hee Kim · 2022 · International Journal of Molecular Sciences
11. DYRK1A is a multifunctional host factor that regulates coronavirus replication in a kinase-independent manner
    Zhenfang Fu, Yixin Xiang, Yanan Fu, Zhelin Su, Yubei Tan, Meng-Fang Yang, Yuanyuan Yan, Hakimeh Baghaei Daemi, Yue-Jun Shi, Sheng-Song Xie et al. · 2023 · Journal of Virology
12. Monoclonal antibodies to activated CDK4: use to investigate normal and cancerous cell cycle regulation and involvement of phosphorylations of p21 and p27
    Katia Coulonval, Vincent Vercruysse, Sabine Paternot, Jaime Miguel Gomes Pita, Robert Corman, Eric Raspé, Pierre P. Roger · 2021 · Cell Cycle
13. Piriform cortex alterations in the Ts65Dn model for down syndrome
    Josep Carbonell, José Miguel Blasco‐Ibáñez, Carlos Crespo, Juan Nácher, Emilio Varea · 2020 · Brain Research
14. Differential regulation of expression of the protein kinases DYRK1A and DYRK1B in cancer cells
    Vincent Andreas Vorwerk, Gerrit Wilms, Aaron Babendreyer, Walter B. Becker · 2024 · Scientific Reports
15. DYRK1A aggravates β cell dysfunction and apoptosis by promoting the phosphorylation and degradation of IRS2
    Mei Lü, Lin Ma, Peiyan Shan, Aifen Liu, Xiaolin Yu, Wenjing Jiang, Xinbang Wang, Xinjing Zhao, Xiang Ye, Tan Wang · 2019 · Experimental Gerontology
16. Live imaging of transforming growth factor‐β activated kinase 1 activation in Lewis lung carcinoma 3 LL cells implanted into syngeneic mice and treated with polyinosinic:polycytidylic acid
    Saori Takaoka, Yuji Kamioka, Kanako Takakura, Ai Baba, Hiroaki Shime, Tsukasa Seya, Michiyuki Matsuda · 2016 · Cancer Science
17. Generation of improved human cerebral organoids from single copy DYRK1A knockout induced pluripotent stem cells in trisomy 21: hypothetical solutions for neurodevelopmental models and therapeutic alternatives in down syndrome
    E. Çağlayan · 2016 · Cell Biology International
18. Organizational Events
    Hannah C. Kinney, Joseph J. Volpe · 2017 · Elsevier eBooks
19. DYRK1A interacts with the tuberous sclerosis complex and promotes mTORC1 activity
    Pinhua Wang, Sunayana Sarkar, Menghuan Zhang, Tingting Xiao, Fenhua Kong, Zhe Zhang, Deepa Balasubramanian, Nandan Jayaram, Sayantan Datta, Ruyu He et al. · 2023 · eLife
20. Using zebrafish as an animal model for studying rare neurological disorders: A human genetics perspective
    Dilan Wellalage Don, Tae‐Ik Choi, Tae-Yoon Kim, Kang‐Han Lee, Yoonsung Lee, Cheol‐Hee Kim · 2024 · Journal of genetic medicine
21. DYRK1A in the physiology and pathology of the neuron-astrocyte axis
    Pablo Cisternas, Ji-Yoon Kim, Brandon L. Ashfeld, Jeremiah J. Zartman · 2025 · Frontiers in Neuroscience
22. Retraction Note to “SDF-1/CXCR4 Axis Regulates Cell Cycle Progression and Epithelial-Mesenchymal Transition via Up-regulation of Survivin in Glioblastoma”
    Anyan Liao, Ranran Shi, Yuliang Jiang, Suqing Tian, Panpan Li, Fuxi Song, Yalan Qu, Jinna Li, Haiqin Yun, Xiangshan Yang · 2017 · Molecular Neurobiology · Retracted
23. Mirk/Dyrk1B controls ventral spinal cord development via Shh pathway
    Nikolaos Kokkorakis, Katerina Douka, A. Nalmpanti, Panagiotis K. Politis, Laskaro Zagoraiou, Rebecca Matsas, Maria Gaitanou · 2024 · Cellular and Molecular Life Sciences
24. Unlocking the Therapeutic Potential of the Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitors in Alzheimer’s Diseases
    Dipanjan Karati, Shreyasi Meur, Ankur Saha, Trina Saha, Aratrika Sen · 2025 · Molecular Neurobiology
25. DYRK1A inhibitors leucettines and TGF-β inhibitor additively stimulate insulin production in beta cells, organoids, and isolated mouse islets
    Barbara Pucelik, Agata Barzowska, Anna Czarna · 2023 · PLoS ONE
26. Growth Arrest Triggers Extra-Cell Cycle Regulatory Function in Neurons: Possible Involvement of p27kip1 in Membrane Trafficking as Well as Cytoskeletal Regulation
    Takeshi Kawauchi, Yo‐ichi Nabeshima · 2019 · Frontiers in Cell and Developmental Biology
27. Molecular causes of primary microcephaly and related diseases: a report from the UNIA Workshop
    Travis H. Stracker, Ciaran G. Morrison, Fanni V. Gergely · 2020 · Chromosoma
28. Real-Time Analysis of Neuronal Cell Cultures for CNS Drug Discovery
    Millicent Tambari Akere, Kelsee K. Zajac, James D. Bretz, Anvitha R. Madhavaram, Austin Horton, Isaac T. Schiefer · 2024 · Brain Sciences
29. DYRK1A interacts with the tuberous sclerosis complex and promotes mTORC1 activity
    Pinhua Wang, Sunayana Sarkar, Menghuan Zhang, Tingting Xiao, Fenhua Kong, Zhe Zhang, Deepa Balasubramanian, Nandan Jayaram, Sayantan Datta, Ruyu He et al. · 2024 · eLife
30. Cyclin D1 Again Caught in the Act: Dyrk1a Links G1 and Neurogenesis in Down Syndrome
    Ian Smith, Federico Calegari · 2015 · EBioMedicine
31. Prenatal treatment with preimplantation factor improves early postnatal neurogenesis and cognitive impairments in a mouse model of Down syndrome
    Manon Moreau, Rodolphe Dard, Amélia Madani, Janany Kandiah, Nadim Kassis, Jessica Ziga, Héloïse Castiglione, Solenn Day, Thomas Bourgeois, Boris Matrot et al. · 2024 · Cellular and Molecular Life Sciences
32. Tumor cell dormancy: Molecular mechanisms, and pharmacological approaches to target dormant cells for countering tumor
    Muhammad Usama Saeed, Nazim Hussain, Iqra Zulfiqar, Ali Raza, Mohsin Ahmad Ghauri, Muhammad Bilal · 2022 · Journal of Drug Delivery Science and Technology
33. Mnb/Dyrk1Aorchestrates a transcriptional network at the transition from self-renewing neurogenic progenitors to postmitotic neuronal precursors
    Shaikh Mirja Nurunnabi, Francisco J. Tejedor · 2018 · Journal of Neurogenetics
34. Retraction Note to: TGF-β Regulates Survivin to Affect Cell Cycle and the Expression of EGFR and MMP9 in Glioblastoma
    Wenliang Chen, Xiao Yan Zhong, Yi Wei, Yun Liu, Yi Quan, Gen‐Shui Zhang, Lishan He, Fajiang Chen, Yingping Liu, Jiandong Luo · 2017 · Molecular Neurobiology · Retracted
35. Revisiting the Sphenoid Sinus Anatomy in Trisomy 21: A CT Study
    Bilal Arslan, Mehmet Zeki Erdem, Abdülaziz Yalınkılıç, Abdulmutalip Karaaslanlı, Burhan Beğer, Bülent Sönmez, Turan Koç, Mitat Selçuk Bozhöyük, Uğur Taşkin Kaplan, Ömer Faruk Cıhan et al. · 2025 · Journal of Craniofacial Surgery
36. Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 induced pluripotent stem cell-derived neural cells
    Nicole R. West, Mattias F. Lindberg, Julien Dairou, Shawn MacGregor, Sahith Puthireddy, Laurent Meijer, Anita Bhattacharyya · 2026 · Disease Models & Mechanisms
37. Regulation of Microtubule: Current Concepts and Relevance to Neurodegenerative Diseases
    Anirban Ghosh, Shamsher Singh · 2021 · CNS & Neurological Disorders - Drug Targets
38. Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C
    Sara Ullsten, Kine Østnes Hansen, Guillaume A. Petit, Espen Holst Hansen, Jeanette Hammer Andersen · 2025 · Scientific Reports
39. A cluster of protein kinases and phosphatases modulated in fetal Down syndrome (trisomy 21) brain
    Rachel Weitzdoerfer, Núria Torán, Saraswathi Subramaniyan, Arnold J. Pollak, Mara Dierssen, Gert Lübec · 2015 · Amino Acids
40. A Munc18-1 mutant mimicking phosphorylation by Down Syndrome-related kinase Dyrk1a supports normal synaptic transmission and promotes recovery after intense activity
    Jessica Classen, Ingrid Saarloos, Marieke Meijer, Patrick F. Sullivan, Matthijs Verhage · 2020 · Scientific Reports
41. ReN VM spheroids in matrix: A neural progenitor three-dimensional in vitro model reveals DYRK1A inhibitors as potential regulators of radio-sensitivity
    Xiao Wan, Xiaoning Wu, Mark A. Hill, Daniel V. Ebner · 2020 · Biochemical and Biophysical Research Communications
42. Genetic interactions and co-operating effects of non-HSA21 genes on the phenotypic variability in Down syndrome
    Bani Bandana Ganguly, Nitin N. Kadam · 2024 · Gene Reports
43. Sella Turcica Dimension and Shape in Trisomy 21: A CT Examination
    Sibel Özalp, Mehmet Zeki Erdem, Abdülaziz Yalınkılıç, Abdulmutalip Karaaslanlı, Burhan Beğer, Bülent Sönmez, Bilal Arslan, Hadice Uçar, Turan Koç, Mitat Selçuk Bozhöyük et al. · 2025 · Journal of Craniofacial Surgery
44. Targeting NAT10 alleviates colonic senescence and elderly-onset colitis by disrupting N4-acetylation of DYRK1A
    Jingyu Chen, Meng Xue, Shuyi Mi, Anbo Fu, Wenwen Chen, Yuhao Sun, Sheng Xia, Qiwei Ge, Jiakai Luo, Qiao Yu et al. · 2026 · Nature Communications
45. DYRK1A and Parkinson’s disease, facts and hypotheses
    Laurent Meijer, Mattias F. Lindberg, Gaëlle Hogrel, Bernard Khor · 2026 · Neurobiology of Disease
46. Nitrogen-Doped Graphene Quantum Dots Conjugated to Leucettinib-21 Rescue Differentiating Zebrafish Purkinje Cells by Inhibiting Dyrk1A Kinase
    Luiza Araújo Gusmão, Annemarie Metzke, Emmanuel Deau, Laurent Meijer, Antônio Cláudio Tedesco, Reinhard Wolfgang Köster · 2026 · ACS Applied Nano Materials
47. Network modeling predicts how DYRK1A inhibition promotes cardiomyocyte cycling after ischemia/reperfusion injury
    Bryce Cameron Murillo, Alexander Young, Kaitlyn L. Wintruba, Alexander J Eichert, Klara Siejda, Dennon Hoernig, Leigh A. Bradley, Bryana N. Harris, Catherine Zhao, MIchelle Wu et al. · 2026 · JCI Insight
48. Dyrk1a
    Francisco J. Tejedor · 2017 · Springer eBooks
49. Craniofacial dysmorphology in Down Syndrome is caused by increased dosage of Dyrk1a and at least three other genes
    Yushi T. Redhead, Dorota Gibbins, Eva Lana‐Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J. Liu, Elizabeth Fisher, Jeremy B. A. Green, Victor L. J. Tybulewicz · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
50. ROCK2 Knockout Improves Proliferation Rate in a Cellular Model of Down Syndrome
    Janine LeBlanc-Straceski, Riley Williams, Kylie Ward, Autumn Bates, Catherine Duran, Lordina Anderson, Morgan Murray, Jennifer Pereira-Badji, Christina Shoushani, Jacob Thibault · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
51. Insights into phosphoproteomic studies and prospects of phosphoproteins as biomarkers for brain disorders
    Jingyang Le, Xuefei Hu, Yujie Jiang, Q. Wang, Q. Ma, Wei Cui · 2026 · Journal of Alzheimer s Disease
52. Emerging roles of DYRK-mediated DNA damage response in cancer
    Lianbao Cao, Shanshan Gao, Chao Dong · 2026 · Genes & Diseases
53. Targeting DYRKs in Cardiovascular Diseases: From Biological Mechanisms to Therapeutic Translation
    Long Jiang, Siyu Peng, Junchen Ma, Liu Tingfei, Xiaoru Long, Lin Li, Hai-Hua Wu · 2026 · International Journal of Molecular Sciences
54. Organizational Events
    Robin Lynn Haynes, Hannah C. Kinney, Joseph J. Volpe · 2024 · Elsevier eBooks
55. The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
    Taylar Hammond, Jong Bin Choi, Miles W. Membreño, János Demeter, Roy Ng, Debadrita Bhattacharya, Thuyen N. Nguyen, Griffin G. Hartmann, Caterina I. Colón, Carine Bossard et al. · 2026 · eLife
56. Dyrk1a
    Francisco J. Tejedor · 2016 · Springer eBooks
57. The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
    Taylar Hammond, Jong Bin Choi, Miles W Membreño, János Demeter, Roy Ng, Debadrita Bhattacharya, Thuyen N. Nguyen, Griffin G. Hartmann, Caterina I. Colón, Carine Bossard et al. · 2025 · eLife
58. Assembly and regulation of the DREAM complex
    Jessica G. Felthousen · 2016 · VCU Scholars Compass (Virginia Commonwealth University)
59. Undifferentiated Small Cell Tumors of the Hepatobiliary Tract
    Arthur Zimmermann · 2016 · Springer eBooks
60. Identification of New IRS1 Interactors in the Regulation of Insulin Signalling and Cell Proliferation
    Scott Frendo‐Cumbo · 2021 · TSpace (University of Toronto)
61. Undifferentiated Small Cell Tumors of the Hepatobiliary Tract
    Arthur Zimmermann · 2016 · Springer eBooks
62. Kinase-independent activity of DYRK1A promotes viral entry of highly pathogenic human coronaviruses
    Madison S. Strine, Wesley L. Cai, Jin Wei, M. M. Alfajaro, R. Filler, Scott B. Biering, Sylvia A. Sarnik, A. Patil, Kasey S. Cervantes, Clayton K. Collings et al. · 2022 · bioRxiv
63. WITHDRAWN: DYRK1A-mediated PLK2 phosphorylation regulates proliferation and invasion of glioblastoma cell
    Shichuan Tan, Juan Zhao, Pin Wang · 2023 · Research Square
64. WITHDRAWN: DYRK1A-mediated PLK2 phosphorylation regulates proliferation and invasion of glioblastoma cell
    2023 · Research Square
65. DYRK1A Interacts with the Tuberous Sclerosis Complex and Promotes mTORC1 Activity
    Pinhua Wang, Sunayana Sarkar, Huan Zhang, Zhe Zhang, Deepa Balasubramanian, Nandan Jayaram, Sayantan Datta, Ruyu He, Ping Wu, Chao Peng et al. · 2023 · eLife
66. Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A
    Eva Lana‐Elola, Rifdat Aoidi, Miriam Llorian, Dorota Gibbins, Callan L Buechsenschuetz, Claudio Bussi, Helen R. Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie Haugsten Hansen et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
67. DYRK1A Interacts with the Tuberous Sclerosis Complex and Promotes mTORC1 Activity
    Pinhua Wang, Sunayana Sarkar, Menghuan Zhang, Tingting Xiao, Fenhua Kong, Zhe Zhang, Deepa Balasubramanian, Nandan Jayaram, Sayantan Datta, Ruyu He et al. · 2024 · eLife
68. DYRK1A Proteins: Key Regulators in Neurodevelopment and Cellular Processes
    Ece Uğur, İdris Arslan · 2025 · Lecture notes in networks and systems
69. Down Syndrome: Progress in Defining Pathogenesis and Treatments for Neurodevelopmental Deficits and Alzheimer’s Disease
    Renata Bartesaghi, Xu‐Qiao Chen, Aaron D. Johnstone, Utpal Das, William Cary Mobley · 2025 · Springer eBooks
70. Novel small-molecule inhibitors of the protein kinase DYRK: Potential therapeutic candidates in cancer
    Prabhadevi Venkataramani, Elad Elkayam, Ankur Garg, Kai Fan Cheng, Ahmad S. Altiti, Mingzhu He, Khushabu Thakur, Evdokia Michalopoulou, Camila Gonzalez, Christy Felice et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
71. THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
    Taylar Hammond, Jong Bin Choi, Miles W Membreño, János Demeter, Roy Ng, Debadrita Bhattacharya, Thuyen N. Nguyen, Griffin G. Hartmann, Caterina I. Colón, Carine Bossard et al. · 2025 · eLife
72. Leucettinib-21 decreases dosage effects of DYRK1A in human trisomy 21 iPSC-derived neural cells
    Nicole R. West, Mattias F. Lindberg, Julien Dairou, Shawn MacGregor, Sahith Puthireddy, Laurent Meijer, Anita Bhattacharyya · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
73. Ocular manifestations in DYRK1A mutation: a five-case series from South Korea
    S. Yang, Jun Ho Boo, Heeyoung Choi, Su-Jin Kim, Kun-Che-On Chong, Seung-Min Lee, Ji-Eun Lee · 2026 · Ophthalmic Genetics
74. The DYRK Family: A Key Regulator of Metabolic Homeostasis and Its Therapeutic Potential in Kidney Diseases
    Yixuan Zhu, Peng-Fei Qiao, Yukun Gan, Xiushuo Fu, Xiayue Huang, Sirui Sun, Ya-Fei Gou, Wenjie Xia, Feng Ma, Limin Liu · 2026 · MedComm – Future Medicine
75. THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
    Taylar Hammond, Jong Bin Choi, Miles W. Membreño, János Demeter, Roy Ng, Debadrita Bhattacharya, Thuyen N. Nguyen, Griffin G. Hartmann, Caterina I. Colón, Carine Bossard et al. · 2026 · eLife
76. Crista Galli Morphology in Patients With Trisomy 21: A Computed Tomography-Based Analysis
    Mehmet Zeki Erdem, Abdülaziz Yalınkılıç, Abdulmutalip Karaaslanlı, Burhan Beğer, Bülent Sönmez, Ömer Erdağ, Murat Gölpınar, Ömer Faruk Cihan, Orhan Beğer · 2026 · Journal of Craniofacial Surgery
77. Sphenoid Ridge in Trisomy 21: A CT-Based Morphometric Evaluation
    Abdülaziz Yalınkılıç, Abdulmutalip Karaaslanlı, Burhan Beğer, Mehmet Zeki Erdem, Ibrahim Ilık, Ayşenur G. Ağabilmez, Veysel Tahiroğlu, Sibel Özalp, Mert Çetin, Orhan Beğer · 2026 · Journal of Craniofacial Surgery
78. Caractérisation et modélisation des pathologies lymphoïdes présentant des gains du chromosome 21
    Anouchka P. Laurent · 2019
79. Correction des déficits cognitifs chez des modèles murins de trisomie 21 par un inhibiteur de la kinase DYRK1A : étude pharmacologique et mécanistique
    Thu-Lan Nguyen · 2017
80. Longitudinal analysis of brain networks by magnetic resonance imaging (MRI) in a murine model of neuropathic pain-induced depression
    Meltem Karatas · 2019 · theses.fr (ABES)
81. Recherches de biomarqueurs impliqués dans la maladie d’Alzheimer et associés à la protéine DYRK1A dans le syndrome de Down pour valider des traitements potentiels
    Yuchen Gu · 2020 · theses.fr (ABES)
82. Étude du neurodéveloppement et de l'infertilité masculine chez différents modèles murins de Trisomie 21
    Rodolphe Dard · 2024
83. Mapping the genetic landscape of HNF1B-dependent cell growth
    Deborah Gaglioti · 2024
84. Phosphoproteomics identifies the DYRK1B protein kinase as a regulator of processing bodies
    Anne L. Ashford, Suzan Ber, Miriam Ems, Emma Duncan, Kathryn Balmanno, Hannah Reeves, Rachael Louise Huntly, Megan A. Cassidy, Harvey E. Johnston, David Oxley et al. · 2026 · Journal of Cell Science
85. LONG-TERM NEURODEVELOPMENTAL AND COGNITIVE OUTCOMES FOLLOWING PRENATAL INHIBITION OF DYRK1A BY LEUCETTINE L41 IN MOUSE MODELS OF DOWN SYNDROME
    Arnaud Duchon, Claire Chevalier, Patrick Gizzi, Julien Dairou, Yann Hérault · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
86. From Structure to Selectivity: Integrating CADD and AIDD in Rational Medicinal Chemistry Strategies for DYRK1A Inhibitor Discovery
    Minghui Yu, Shuangtian Tang, Lijuan Huang, Yunyue Wang, Jinyi Xu, Huajian Zhu, Hong Yao · 2026 · Journal of Medicinal Chemistry
87. Integrative Insights Into DYRK1A From Molecular Function to Therapeutic Advancement
    Sampriti Paul, Sonal Dubey, Prashant Tiwari · 2026 · Chemical Biology and Drug Design
88. BindingDB Entry 50016861: DYRK1A inhibitors for disease therapy: Current status and perspectives.
    BindingDB · 2023 · UC San Diego
89. BindingDB Entry 50022831: A review on synthetic inhibitors of dual-specific tyrosine phosphorylation-regulated kinase 1A (DYRK1A) for the treatment of Alzheimer's disease (AD).
    BindingDB · 2026 · UC San Diego
90. BindingDB Entry 50003093: Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
    BindingDB · 2020 · UC San Diego
91. BindingDB Entry 50016614: Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A.
    BindingDB · 2023 · UC San Diego
92. BindingDB Entry 50017060: Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.
    BindingDB · 2023 · UC San Diego
93. BindingDB Entry 50016090: Development of novel conformationally restricted selective Clk1/4 inhibitors through creating an intramolecular hydrogen bond involving an imide linker.
    BindingDB · 2023 · UC San Diego
94. UNDERSTANDING THE FUNCTION OF DYRK1A THROUGH CHARACTERIZATION OF ITS INTERACTING PROTEINS
    Varsha Ananthapadmanabhan · 2015 · VCU Scholars Compass (Virginia Commonwealth University)