Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program

Blagosklonny, Mikhail V·2010·Cell Cycle

Cited by (161)

Items 101–161 of 161

  1. Telomerase activity is upregulated in the fat bodies of pre-diapause bumblebee queens (Bombus terrestris)
    Justina Koubová, Tomáš Jehlík, Dalibor Kodrı́k, Michala Sábová, Peter Šima, Hana Sehadová, Radka Závodská, Radmila Čapková Frydrychová · 2019 · Insect Biochemistry and Molecular Biology
  2. Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes
    A. E. Berman, Olga V. Leontieva, Venkatesh Natarajan, James Andrew McCubrey, Zoya N. Demidenko, Mikhail A. Nikiforov · 2012 · Oncotarget
  3. Rethinking modern theories of ageing and their classification: the proximate mechanisms and the ultimate explanations
    Piotr Paweł Chmielewski · 2017 · Anthropological Review
  4. Translational regulation in stress biology
    Naomi R. Genuth, Andrew G. Dillin · 2025 · Nature Cell Biology
  5. Aging biology: a new frontier for drug discovery
    Ester Verdaguer, Fèlix Junyent, Jaume Folch, Carlos Beas‐Zárate, Carme Auladell, Mercè Pallàs, Antoni Camins · 2012 · Expert Opinion on Drug Discovery
  6. Ageing as “early-life inertia”: Disentangling life-history trade-offs along a lifetime of an individual
    Hanne Carlsson, Edward R. Ivimey‐Cook, Elizabeth Duxbury, Nathan Edden, Kris Sales, Alexei A. Maklakov · 2021 · Evolution Letters
  7. A novel role of the mitochondrial iron-sulfur cluster assembly protein ISCU-1/ISCU in longevity and stress response
    Yi Sheng, Guang Yang, Kaitlyn Casey, Shayla Curry, Mason Oliver, Sung Min Han, Christiaan Leeuwenburgh, Rui Xiao · 2021 · GeroScience
  8. Evolution of Aging and Death: What Insights Bacteria Can Provide
    Ulfat I. Baig, Bharati J. Bhadbhade, Milind Watve · 2014 · The Quarterly Review of Biology
  9. Recent discoveries in the cycling, growing and aging of the p53 field
    James Andrew McCubrey, Zoya N. Demidenko · 2012 · Aging
  10. Drosophila Sirtuin 6 mediates developmental diet‐dependent programming of adult physiology and survival
    Namrata Shukla, Ullas Kolthur‐Seetharam · 2022 · Aging Cell
  11. Evidence that a mitochondrial death spiral underlies antagonistic pleiotropy
    Michael Stern · 2017 · Aging Cell
  12. Wt p53 impairs response to chemotherapy: make lemonade to spare normal cells
    Mikhail V. Blagosklonny · 2012 · Oncotarget
  13. Metformin and sex: why suppression of aging may be harmful to young male mice
    Mikhail V. Blagosklonny · 2010 · Aging
  14. Rapamycin treatment early in life reprograms aging: hyperfunction theory and clinical practice
    Mikhail V. Blagosklonny · 2022 · Aging
  15. As predicted by hyperfunction theory, rapamycin treatment during development extends lifespan
    Blagosklonny, Mikhail V. · 2022 · Aging
  16. Inflammaging: inflammation and oxidative stress as a cause of aging and cognitive decline
    Anton P. Pereverzev, R. R. Romanovsky, N. A. Shatalova, Ol'ga Dmitrievna Ostroumova · 2021 · Meditsinskiy sovet = Medical Council
  17. Telomerase as a possible key to bypass reproductive cost
    Radmila Čapková Frydrychová · 2023 · Molecular Ecology
  18. Commentary: Life course epidemiology embraces geroscience
    Luigi Ferrucci · 2016 · International Journal of Epidemiology
  19. RHEB1 insufficiency in aged male mice is associated with stress-induced seizures
    Qi Tian, Pavel Gromov, Joachim H. Clement, Yingming Wang, Marc Riemann, Falk Weih, Xiao‐Xin Sun, Mu‐Shui Dai, Lev M. Fedorov · 2017 · GeroScience
  20. Modalities of aging in organisms with different strategies of resource allocation
    Alexander Suvorov · 2022 · Ageing Research Reviews
  21. Differential proteomics reveals age-dependent liver oxidative costs of innate immune activation in mice
    Marine I. Plumel, Margaux Benhaim-Delarbre, Magali Rompais, Danièle Thiersé, Gabriele Sorci, Alain VAN DORSSELAER, François Criscuolo, Fabrice Bertile · 2015 · Journal of Proteomics
  22. How ageing increases cancer susceptibility: A tale of two opposing yet synergistic views
    Sylvia Oghogho Omage, Kingsley Omage · 2016 · Genes & Diseases
  23. RETRACTED ARTICLE: A Negative-Feedback Loop between the Detoxification/Antioxidant Response Factor SKN-1 and Its Repressor WDR-23 Matches Organism Needs with Environmental Conditions
    Chi Kwan Leung, Ying Wang, Andrew Deonarine, Lanlan Tang, Stephanie Prasse, Keith Patrick Choe · 2013 · Molecular and Cellular Biology · Retracted
  24. Colony level fitness analysis identifies a trade-off between population growth rate and dauer yield in Caenorhabditis elegans
    Hannah Chapman, Kuei Ching Hsiung, Isadora Rawlinson, Evgeniy R. Galimov, David Gems · 2024 · BMC Ecology and Evolution
  25. On the cause and mechanism of phenoptosis
    Richard F. Walker · 2017 · Biochemistry (Moscow)
  26. Theories of Human Aging of Molecules to Society
    Ángel Julio RC · 2015 · MOJ Immunology
  27. The Western diet as payback for civilization: pathophysiological mechanisms and issues for discussion
    Oksana M. Drapkina, Ким О. Т., В.А. Дадаева · 2021 · Russian Journal of Preventive Medicine
  28. A Cell Size Theory of Aging
    Krushna Chandra Patra, Nabeel M. Bardeesy · 2018 · Developmental Cell
  29. Late-life dietary folate restriction reduces biosynthesis without compromising healthspan in mice
    Heidi M. Blank, Staci E. Hammer, Laurel Boatright, Courtney Roberts, Katarina E. Heyden, Aravindh Nagarajan, Mitsuhiro Tsuchiya, Marcel Brun, Charles D. Johnson, Patrick J. Stover et al. · 2024 · Life Science Alliance
  30. Cancer and Aging
    Arti Hurria, Hyman Bernard Muss, Harvey Jay Cohen · 2017 · Wiley eBooks
  31. Autophagy-dependent gut-to-yolk biomass conversion generates visceral polymorbidity in aging C. elegans
    Marina Ezcurra, Alexandre Benedetto, Thanet Sornda, Ann F. Gilliat, Catherine Au, Qifeng Zhang, Sophie van Schelt, Alexandra L. Petrache, Yila de la Guardia, Shoshana Bar‐Nun et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Multifaceted aging and rapamycin
    Vladimir Nikolaevich Anisimov · 2013 · Aging
  33. Remodeling of the Extracellular Matrix in the Aging Lung
    Jesse Roman · 2014 · Wiley eBooks
  34. Amniotic fluid stem cells to study mTOR signaling in differentiation
    Margit Rosner, Katharina Schipany, Bharanidharan Shanmugasundaram, Gert Lübec, Oliver Brandau, Markus Hengstschläger · 2012 · Organogenesis
  35. The Connection between Cellular Senescence and Age-Related Diseases
    Claire Falandry · 2019 · Cambridge University Press eBooks
  36. How does the body know how old it is?
    Josh Mitteldorf · 2023 · Experimental Gerontology
  37. Ansätze der Biogerontologie
    David Gems · 2021 · J.B. Metzler eBooks
  38. Immunosenescence shapes the tumor immune microenvironment and limits PD-1/PD-L1 blockade efficacy in older patients with cancer
    Xiaoyu Niu, Ziwaregul Nur, Wenkang Xie, Yang Sun, L F Wang, Yuanyuan Zheng · 2026 · Frontiers in Immunology
  39. Organelle Stress and mTOR in Aging-Associated Inflammation
    Giovambattista Pani · 2013 · Elsevier eBooks
  40. Circadian Clock Mechanisms Link Aging and Inflammation
    Anna A. Kondratova, Roman V. Kondratov · 2013 · Elsevier eBooks
  41. The Evolving Opportunistic Pathogen Communities on Host Individuals and the Evolution of Host Aging
    Ulfat I. Baig, Akanksha Ojha, Milind Watve · 2017 · Journal of Evolutionary Medicine
  42. Nutrition in the Elderly
    Eugenio Mocchegiani · 2016 · Elsevier eBooks
  43. TOR: The ancient link between cancer and ageing?
    Andrew Moore · 2012 · BioEssays
  44. Ageing in the mammalian brain
    Sohair M. Khojah · 2015 · Enlighten: Theses (The University of Glasgow)
  45. Epigenetic signature in persons with Down Syndrome
    Fontanesi, Elisa <1984> · 2015 · AMS Dottorato Institutional Doctoral Theses Repository (University of Bologna)
  46. The Biology of Immortality
    Henry G. Stratmann · 2015 · Science and fiction
  47. The hammer of TORC1!
    Éric Dufour · 2015 · Cell Cycle
  48. Mechanisms Underlying Regulation of Yeast Longevity by Genetic and Pharmacological Interventions that Alter Mitochondrial Membrane Lipidome and Remodel Mitochondrial Respiratory Supercomplexes
    Olivia Koupaki · 2012 · Spectrum Research Repository (Concordia University)
  49. her2 hyper-activation through the production of carboxy-terminal fragments
    Pier Davide Angelini · 2014 · TDX (Tesis Doctorals en Xarxa)
  50. The Role of Apoptosis and Necrosis in Age-Dependent Enzymatic Mitochondrial Abnormalities in Individual Skeletal Muscle Fibers
    Nashwa Cheema · 2017 · ERA: Education and Research Archive (University of Alberta)
  51. The role of the C. elegans daf-2(e1370) metabolic shift in longevity and stress resistance
    Aleksandra Zečić · 2021 · Ghent University Academic Bibliography (Ghent University)
  52. Faculty Opinions recommendation of C. elegans eats its own intestine to make yolk leading to multiple senescent pathologies.
    L. Ryan Baugh · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  53. Faculty Opinions recommendation of Experimentally reduced insulin/IGF-1 signaling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring.
    Daniel H. Nussey · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  54. Selection by differential mortality rates
    Moiseis dos Santos Cecconello, Raul Abreu de Assis, Luciana Mafalda Elias de Assis, Ezio Venturino · 2021 · Applied Mathematics and Nonlinear Sciences
  55. Additional file 1 of Colony level fitness analysis identifies a trade-off between population growth rate and dauer yield in Caenorhabditis elegans
    Chapman, Hannah, Kuei Ching Hsiung, Isadora Rawlinson, Evgeniy R. Galimov, David Gems · 2024 · Figshare
  56. On aging and the role of Ubp3 in heterochromatic gene silencing and protein quality control
    David Öling · 2014 · Gothenburg University Publications Electronic Archive (Gothenburg University)
  57. From hyperfunction to systemic amplification: reframing the logic of late-life rejuvenation
    Pierre‐Edouard Sottas · 2026 · Aging
  58. Why we age: the four process model
    James Wordsworth, Pernille Yde Nielsen, Edward Fielder, Sharmilla Chandrasegaran, Daryl P. Shanley · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Développements méthodologiques en protéomique quantitative pour mieux comprendre la biologie évolutive d'espèces non séquencées
    Margaux Benhaim-Delarbre · 2017 · theses.fr (ABES)
  60. Molecular links between nutrition, reproduction and aging
    Manjunatha Thondamal · 2014 · theses.fr (ABES)
  61. Zelluläre Mechanismen des Alterns
    Ludger Rensing, Volkhard Rippe · 2013 · Springer eBooks