Production, characterization, and pharmacokinetic properties of antibodies with N-linked mannose-5 glycans
Yu, Marcella, Brown, Darren, Reed, Chae, Chung, Shan, Lutman, Jeff, Stefanich, Eric, Wong, Anne, Stephan, Jean-Philippe +1 more·2012·mAbs
Cited by (203)
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- Comparison of CD20 Binding Affinities of Rituximab Produced in Nicotiana benthamiana Leaves and Arabidopsis thaliana CallusCho Eun Kang, Seungeun Lee, Dong Hye Seo, Woon Heo, Sun Hyung Kwon, JeongRyeol Kim, Jinu Lee, Hisashi Koiwa, Hisashi Koiwa, Joo Young Kim et al. · 2021 · Molecular Biotechnology
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- Drug Safety2013 · Drug Safety
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