The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Testosterone signaling and the regulation of spermatogenesis
Open accessAbstract
Spermatogenesis and male fertility are dependent upon the presence of testosterone in the testis. In the absence of testosterone or the androgen receptor, spermatogenesis does not proceed beyond the meiosis stage. The major cellular target and translator of testosterone signals to developing germ cells is the Sertoli cell. In the Sertoli cell, testosterone signals can be translated directly to changes in gene expression (the classical pathway) or testosterone can activate kinases that may regulate processes required to maintain spermatogenesis (the non-classical pathway). Contributions of the classical and non-classical testosterone signaling pathways to the maintenance of spermatogenesis are discussed. Studies that may further elaborate the mechanisms by with the pathways support spermatogenesis are proposed.
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Cites
The Physiology of Reproduction
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,861
The central role of Sertoli cells in spermatogenesis
Griswold, M. D. (1998) · Seminars in Cell & Developmental Biology · doi:10.1006/scdb.1998.0203 · Cited by 882
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis
De Gendt, K., Swinnen, J. V., Saunders, P. T. K., Schoonjans, L., Dewerchin, M., Devos, A., Tan, K., Atanassova, N., Claessens, F., Lécureuil, C., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308114100 · Cited by 805
Formation of the Androgen Receptor Transcription Complex
Shang, Y., Myers, M., & Brown, M. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00471-9 · Cited by 672
Migliaccio, A. (2000) · The EMBO Journal · doi:10.1093/emboj/19.20.5406 · Cited by 672
Rey, R. (2003) · Endocrine Development · doi:10.1159/000069300 · Cited by 651
Regulation of E-cadherin/Catenin Association by Tyrosine Phosphorylation
Roura, S., Miravet, S., Piedra, J., de Herreros, A. G., & Duñach, M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.51.36734 · Cited by 603
Chang, C., Chen, Y.-T., Yeh, S.-D., Xu, Q., Wang, R.-S., Guillou, F., Lardy, H., & Yeh, S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307306101 · Cited by 468
Wang, R.-S., Yeh, S., Tzeng, C.-R., & Chang, C. (2009) · Endocrine Reviews · doi:10.1210/er.2008-0025 · Cited by 465
Holdcraft, R. W., & Braun, R. E. (2004) · Development · doi:10.1242/dev.00957 · Cited by 459
Cited by
Endocrine control of spermatogenesis: Role of FSH and LH/ testosterone
Ramaswamy, S., & Weinbauer, G. F. (2014) · Spermatogenesis · doi:10.1080/21565562.2014.996025 · Cited by 411
The role of the microbiome in the neurobiology of social behaviour
Sarkar, A., Harty, S., Johnson, K. V. ‐., Moeller, A. H., Carmody, R. N., Lehto, S. M., Erdman, S. E., Dunbar, R. I. M., & Burnet, P. W. J. (2020) · Biological Reviews · doi:10.1111/brv.12603 · Cited by 135
Female chemical signalling underlying reproduction in mammals
Coombes, H. A., Stockley, P., & Hurst, J. L. (2018) · Journal of Chemical Ecology · doi:10.1007/s10886-018-0981-x · Cited by 98
Marijuana smoking and markers of testicular function among men from a fertility centre
Nassan, F. L., Arvizu, M., Mínguez-Alarcón, L., Williams, P. L., Attaman, J., Petrozza, J., Hauser, R., Chavarro, J., EARTH Study Team, Ford, J. B., et al. (2019) · Human Reproduction · doi:10.1093/humrep/dez002 · Cited by 75
TNF-α-mediated suppression of Leydig cell steroidogenesis involves DAX-1
Sadasivam, M., Ramatchandirin, B., Balakrishnan, S., & Prahalathan, C. (2015) · Inflammation Research · doi:10.1007/s00011-015-0835-8 · Cited by 33
Metadata
- Authors
- Walker, W. H.
- Venue
- Spermatogenesis
- Publisher
- Informa UK Limited
- Published
- 2011-04
- Volume
- 1
- Issue
- 2
- Pages
- 116-120
- ISSN
- 2156-5554 (ISSN-L)
- 2156-5562
- OpenAlex
- W2154831045
- Cited by
- 417
- References
- 50
- FWCI
- 14.13
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
