A Case Study of Gut Fermentation Syndrome (Auto-Brewery) with Saccharomyces cerevisiae as the Causative Organism
Open accessAbstract
Gut Fermentation Syndrome also known as Auto-Brewery Syndrome is a relatively unknown phenomenon in modern medicine. Very few articles have been written on the syndrome and most of them are anecdotal. This article presents a case study of a 61 years old male with a well documented case of Gut Fermentation Syndrome verified with glucose and carbohydrate challenges. Stool cultures demonstrated the causative organism as Saccharomyces cerevisiae. The patient was treated with antifungals and a low carbohydrate diet and the syndrome resolved. Helicobacter pylori was also found and could have been a possible confounding variable although the symptoms resolved post-treatment of the S. cerevisiae.
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There is some evidence to suggest that yeast overgrowth in the gut, usually Candida or Saccharomyces species, can cause an accumulation of ethanol.
“There is some evidence to suggest that yeast overgrowth in the gut, usually Candida or Saccharomyces species, can cause an accumulation of ethanol [79, 80].”
From Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms (2019) · cites this paper as [80]
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References 15 · Cited by 41
Research works printed but not linked: 1
- K. Iwata, "A Review of the Literature on Drunken Syn- dromes Due to Yeasts in the Gastrointestinal Tract," Uni- versity of Tokyo Press, Tokyo, 1972, pp. 260-268.
- Authors
- Cordell, B., & McCarthy, J.
- Affiliations
- Panola College (US)
- Venue
- International Journal of Clinical Medicine
- Publisher
- Scientific Research Publishing, Inc.
- Published
- 2013
- Volume
- 04
- Issue
- 07
- Pages
- 309-312
- ISSN
- 2158-284X (ISSN-L)
- 2158-2882
- OpenAlex
- W2118480671
- Cited by
- 41
- References
- 15
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 4 · 2023: 5 · 2022: 1 · 2021: 5 · 2020: 7 · 2019: 5 · 2018: 2 · 2017: 1 · 2015: 2 · 2014: 1 · 2013: 1
- FWCI
- 0.60
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- International Journal of Clinical Medicine (publishedVersion, cc-by)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Keywords
- auto-brewery syndrome, Saccharomyces cerevisiae, yeast overgrowth, Helicobacter pylori, antifungal therapy, low-carbohydrate diet
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