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Dengue Virus-Specific and Flavivirus Group Determinants Identified with Monoclonal Antibodies by Indirect Immunofluorescence
Abstract
Monoclonal antibodies produced against the four dengue virus serotypes identified four categories of reactions by immunofluorescence: flavivirus group reactive, dengue complex specific, dengue subcomplex specific (DEN-1, DEN-3), and dengue serotype specific. This is the first time that monospecific antibodies have been available for all of these unique antigenic determinants. Hybridoma cell lines producing dengue type-specific antibodies have been deposited in the Hybridoma Cell Bank of the American Type Culture Collection (Rockville, MD) for general distribution.
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Cited by
Antibody-dependent enhancement of severe dengue disease in humans
Katzelnick, L. C., Gresh, L., Halloran, M. E., Mercado, J. C., Kuan, G., Gordon, A., Balmaseda, A., & Harris, E. (2017) · Science · doi:10.1126/science.aan6836 · Cited by 1,205
Zika virus impairs growth in human neurospheres and brain organoids
Garcez, P. P., Loiola, E. C., Madeiro da Costa, R., Higa, L. M., Trindade, P., Delvecchio, R., Nascimento, J. M., Brindeiro, R., Tanuri, A., & Rehen, S. K. (2016) · Science · doi:10.1126/science.aaf6116 · Cited by 1,184
Tabata, T., Petitt, M., Puerta-Guardo, H., Michlmayr, D., Wang, C., Fang-Hoover, J., Harris, E., & Pereira, L. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.07.002 · Cited by 486
Antigenic Structure of Flavivirus Proteins
Roehrig, J. T. (2003) · Advances in Virus Research · doi:10.1016/s0065-3527(03)59005-4 · Cited by 279
Metadata
- Authors
- Henchal, E. A., Gentry, M. K., McCown, J. M., & Brandt, W. E.
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 1982-07
- Volume
- 31
- Issue
- 4
- Pages
- 830-836
- ISSN
- 0002-9637 (ISSN-L)
- OpenAlex
- W12260993
- Cited by
- 448
- References
- 0
- FWCI
- 10.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Dengue Virus-Specific and Flavivirus Group Determinants Identified with Monoclonal Antibodies by Indirect Immunofluorescence. https://app.cochat.ai/papers/10.4269/ajtmh.1982.31.830
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- Henchal, E. A., Gentry, M. K., McCown, J. M., & Brandt, W. E. (1982). Dengue Virus-Specific and Flavivirus Group Determinants Identified with Monoclonal Antibodies by Indirect Immunofluorescence. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.1982.31.830
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.