Production de matières premières et fabrication des médicaments à base de plantes médicinales
Open accessAbstract
Les plantes constituent un réservoir pour les pharmacopées du monde. Plusieurs médicaments importants sont fabriqués à partir des substances actives d’origine végétales. En outre de nombreux médicaments modernes ont été fabriqués à partir de ces matières premières. Les plantes médicinales sont utilisées directement sous forme fraîche, sèche ou transformée, stabilisée, ou extrait ou formulée avec d’autres plantes ou excipients de synthèse. Dans tous les cas, la matière végétale utilisée pour fabriquer la forme posologique doit faire preuve de son efficacité, son innocuité et être de qualité conforme aux exigences de la Pharmacopée Européenne pour les phytomédicaments, garantissant ainsi sa sécurité d’emploi. Pour ce faire, l’Organisation Mondiale de la Santé (OMS) a mis à la disposition des états membres des guides et standards permettant d’harmoniser et de sécuriser leur utilisation. Ainsi de nombreux pays africains ont adopté ces outils après des modifications appropriées pour faire progresser la recherche et le développement (R&D) de médicaments à base de plante. Le but de ce travail était de faire une synthèse des différentes étapes de production, de contrôle qualité et de standardisation des matières premières issues des plantes médicinales et des médicaments à base de plantes médicinales.Mots clés : Pharmacopée, médicaments, médecine traditionnelle, sécurité d’emploi, phytomédicaments. English title: Production of raw materials and manufacturing of drugs from medicinal plants Plants are a reservoir for the world's pharmacopoeias. Several important medicines are made from active substances of plant origin. In addition, many modern medicines have been made from these raw materials. Medicinal plants are used directly in fresh, dry or processed, stabilized, or extracted form or formulated with other plants or synthetic excipients. In all cases, the herbal material used to manufacture the dosage form must demonstrate its efficacy, safety and be of a quality that meets the requirements of the European Pharmacopoeia for phytomedicines, thus ensuring its safe use. To this end, the World Health Organization (WHO) has made available to Member States guides and standards to harmonize and secure their use. Thus, many African countries have adopted these tools after appropriate modifications to advance research and development (R&D) of plant-based drugs. The aim of this work was to make a synthesis of the different stages of production, quality control and standardization of raw materials from medicinal plants and herbal medicines.Keywords: Pharmacopoeia, drugs, traditional medicine, safe use, phytomedicines.
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Herbal medicines can be packaged in liquid forms, including syrup, thanks to modern technology in commercial production.
“According to Ouedraogo et al. (2021), herbal medicines can be packaged in liquid forms, including syrup, thanks to the introduction of modern technology in the commercial production of herbal products.”
From Ethnomedicine, improved traditional medicine from Cocos nucifera water and evaluation of antibacterial activity on four bacterial strains in Center, Cameroon (2024) · cites this paper as Ouedraogo et al. 2021
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LAMY, G. M. L., LIKENG, J. L. N., NDJIB, R. C., NDOUNGA, S. E. N., ELOMO, L. B., MBUH, S. M., NNANGA, L. S., MAHAMA, M., BIYON, J. B. N., HARMSEN, K., et al. (2024) · Asian Journal of Natural Product Biochemistry · doi:10.13057/biofar/f220104
- Authors
- Ouedraogo, S., Yoda, J., Traore, T. K., Nitiema, M., Sombie, B. C., Diawara, H. Z., Yameogo, J. B. G., Djande, A., Belemnaba, L., Kini, F. B., Ouedraogo, S., & Semde, R.
- Affiliations
- Université Joseph Ki-Zerbo (BF)
- Centre National de la Recherche Scientifique et Technologique (BF)
- Venue
- International Journal of Biological and Chemical Sciences
- Publisher
- African Journals Online (AJOL)
- Published
- 2021-06-23
- Volume
- 15
- Issue
- 2
- Pages
- 750-772
- ISSN
- 1991-8631 (ISSN-L)
- 1997-342X
- OpenAlex
- W3175532520
- Cited by
- 24
- References
- 0
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 8 · 2023: 2 · 2021: 3
- FWCI
- 1.95
- Type
- journal article
- Language
- fr
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- International Journal of Biological and Chemical Sciences (publishedVersion, cc-by-nc-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- medicinal plants, medicinal plant raw materials, herbal medicine, herbal medicine production, quality control, standardization, European Pharmacopoeia, WHO guidelines, traditional medicine, herbal medicine safety, raw material production, plant extracts, herbal formula, pharmaceutical excipients, herbal medicine regulation, standard harmonization
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