BioPhorum 2024 post sterilization pre-use integrity testing (PUPSIT) practice in the biopharmaceutical industry survey findings
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Industry feedback highlighted concerns with PUPSIT complexities including system design, reliable filter wetting, and increased risk of human error.
“Industry feedback highlighted concerns with these complexities including system design, reliable filter wetting, and the increased risk of human error in the more intricate PUPSIT process (BioPhorum Operations Group (BPOG), 2024).”
From Single-use solutions for PUPSIT: requirements, challenges, and solutions (2026) · cites this paper as BioPhorum Operations Group (BPOG), 2024
Additional connections for PUPSIT operations can bring extra risks of dead legs, hold-up volume, or non-conformities, especially on the sterile downstream side of a filter.
“The additional connections for these operations can bring extra risks of dead legs, hold-up volume, or non-conformities, which present a risk especially on the sterile downstream side of a filter.”
From Single-use solutions for PUPSIT: requirements, challenges, and solutions (2026) · cites this paper as BioPhorum Operations Group (BPOG), 2024
Implementing PUPSIT introduces significant technical and operational challenges, including more complex wetting and venting procedures that may bring increased risk of contamination and susceptibility to human error.
“However, implementing PUPSIT introduces significant technical and operational challenges, including more complex wetting and venting procedures that may bring increased risk of contamination and susceptibility to human error.”
From Single-use solutions for PUPSIT: requirements, challenges, and solutions (2026) · cites this paper as BioPhorum Operations Group (BPOG), 2024
Implementing PUPSIT is not without considerable technical and operational challenges, as a survey of drug manufacturers by BioPhorum Operations Group in 2024 shows.
“Implementing PUPSIT is not without considerable technical and operational challenges, as a survey of drug manufacturers by BioPhorum Operations Group in 2024 shows:”
From Single-use solutions for PUPSIT: requirements, challenges, and solutions (2026) · cites this paper as BioPhorum Operations Group (BPOG), 2024
Cited by
Sorted by citations
Single-use solutions for PUPSIT: requirements, challenges, and solutions
Glenz, M., Eiermann, P., Manser, B., & Teschner, H. (2026) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-026-13847-5 · Cited by 1 · see citing works
- Authors
- BioPhorum
- Publisher
- BioPhorum
- Published
- 2024-10-30
- Cited by
- 1
- References
- 0
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
