Cited by 3Dye analysis and toxicityEffects and risks of endocrine disrupting chemicalsAgricultural safety and regulations

Side effects of preservatives on human life

Open access
Mohammed Kamel Ahmed, Tawoos, Mohammed Bakr, Media, Assi Ahmed, Qays·2022·Scientific Research Journal of Pharmacy

Abstract

In order to increase their shelf life, preservatives are essential in the food, cosmetics, and pharmaceutical industries. They prevent microbiological development, preserve flavor, and boost nutritional content. There are two types of preservatives: natural and artificial. Chemical processes are used to create industrial preservatives as more affordable and efficient substitutes. Artificial preservatives are chemicals that are used to preserve food for a longer amount of time; they include antimicrobials, antioxidants, and other ingredients that impede the ripening process naturally. Antimicrobials prevent the breakdown of foods caused by bacteria, and the mechanism of action of these preservatives ranges from preventing bacterial growth to preventing certain enzymes from working.Regardless of the existence of natural preservatives like salt, alcohol, vinegar, and sugar, the food sector deals with poisonous chemicals that are truly connected to a number of diseases and harmful health impacts. Many preservatives have different effects on the human body and therefore research is constantly being done to determine how dangerous they are and remove them from the market . Preservatives have negative effects on human health and the biological system and environmental pollution and cause many diseases and damages to the human body, such as skin sensitivity, discourage the work of the endocrine glands, disrupt the menstrual cycle, and cause tissue disorders in the liver, kidneys, and reproductive organs, in addition to their impact on body weight, balance Oxidative stress and sex hormones. That is why the current article aimed to present the role of preservatives to prevent spoilage of food, medicines and cosmetics, and to know their negative effects on human health.

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  • The use of BHA is prohibited by European regulations and IARC in skin care products including makeup, sunscreens, lip and hair products, fragrance, and creams.

    “The use of BHA is prohibited by European regulations and IARC in skin care products including makeup, sunscreens, lip and hair products, fragrance, and creams (77).”

    From The dark side of beauty: an in-depth analysis of the health hazards and toxicological impact of synthetic cosmetics and personal care products (2024) · cites this paper as [77]

    The Introduction discusses parabens in cosmetics, but does not address BHA or restrictions on its use. Searches of our copy for BHA, European regulations, IARC, and a cosmetic-use prohibition found no passage supporting the claim; the available text does not establish whether the prohibition exists. (LLM, conf=0.75)

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Research works printed but not linked: 113

  1. Rasgele, P.G. and F. Kaymak. “Effects of food preservative natamycin on liver enzymes and total protein in Mus musculus.” Bulgarian Journal of Agricultural Science, vol. 19, 2013, pp. 298–302.
  2. Carocho, M. et al. “Natural food additives: Quo vadis?” Trends in Food Science and Technology, vol. 45, no. 2, 2015, pp. 284–295.
  3. Bräuner, E.V. et al. “Presence of parabens, phenols and phthalates in paired maternal serum, urine and amniotic fluid.” Environment International, vol. 158, 2022, article 106987.
  4. Kim, S. et al. “Urinary parabens and triclosan concentrations and associated exposure characteristics in a Korean population.” International Journal of Hygiene and Environmental Health, vol. 221, no. 4, 2018, pp. 632–641.
  5. Hajizadeh, Y. et al. “Urinary paraben concentrations and their implications for human exposure in Iranian pregnant women.” Environmental Science and Pollution Research, vol. 27, no. 13, 2020, pp. 14723–14734.
  6. Bae, J.S. et al. “Thirteen-week subcutaneous repeated-dose toxicity study of butylparaben and its toxicokinetics in rats.” Archives of Toxicology, vol. 95, no. 6, 2021, pp. 2037–2050.
  7. Park, N.Y. et al. “Parabens in breast milk and possible sources of exposure among lactating women in Korea.” Environmental Pollution, vol. 255, 2019, article 113142.
  8. Song, S. et al. “Profiles of parabens and their metabolites in paired maternal-fetal serum, urine and amniotic fluid.” Ecotoxicology and Environmental Safety, vol. 191, 2020, article 110235.
  9. Matwiejczuk, N. et al. “Review of the safety of application of cosmetic products containing parabens.” Journal of Applied Toxicology, vol. 40, no. 1, 2020, pp. 176–210.
  10. Gonzalez, T.L. et al. “Implication of environmental estrogens on breast cancer treatment and progression.” Toxicology, vol. 421, 2019.
  11. Mogus, J.P. et al. “Exposure to propylparaben during pregnancy and lactation induces long-term alterations to the mammary gland in mice.” Endocrinology, vol. 162, no. 6, 2021, article bqab041.
  12. Yang, C. et al. “Butylparaben promotes apoptosis in human trophoblast cells through oxidative stress-induced endoplasmic reticulum stress.” Environmental Toxicology, vol. 33, no. 4, 2018, pp. 436–445.
  13. Inanli, A.G. et al. “The impact of chitosan on seafood quality and human health: A review.” Trends in Food Science and Technology, vol. 97, 2020, pp. 404–416.
  14. Kumari, P.K. et al. “Alternative to artificial preservatives.” Systematic Reviews in Pharmacy, vol. 10, no. 1S, 2019.
  15. Tfouni, A.S. and M.C. Toledo. “Estimates of the mean per capita daily intake of benzoic and sorbic acids in Brazil.” Food Additives and Contaminants, vol. 19, no. 7, 2002, pp. 647–654.
  16. Thomas, O.E. and O.A. Adegoke. “Toxicity of food colours and additives: A review.” African Journal of Biotechnology, vol. 9, no. 36, 2015, pp. 900–914.
  17. Martyn, D.M. et al. “Food additives and preschool children.” Proceedings of the Nutrition Society, vol. 72, no. 1, 2013, pp. 109–116.
  18. Lennerz, B.S. et al. “Effect of sodium benzoate on glucose homeostasis and metabolic profiles in humans.” Molecular Genetics and Metabolism, vol. 114, no. 1, 2015, pp. 73–79.
  19. Akintonwa, A. et al. “The mutagenic potentials of potassium bromate and commonly used food additives.” African Journal of Biotechnology, vol. 6, no. 8, 2007.
  20. Di Sotto, A. et al. “Genotoxicity assessment of some cosmetic and food additives.” Regulatory Toxicology and Pharmacology, vol. 68, 2014, pp. 16–22.
  21. Antunes, S.C. et al. “Modern preservatives of microbiological stability.” Pharmaceutical Chemistry Journal, vol. 53, no. 6, 2019, pp. 564–571.
  22. Ramalho, V.C. and N. Jorge. “Antioxidants used in oils, fats and fatty foods.” Química Nova, vol. 29, no. 4, 2006, pp. 755–760.
  23. Baptista, R.C. et al. “Natural products with preservative properties for enhancing the microbiological safety and extending the shelf life of seafood.” Food Research International, vol. 127, 2020, article 108762.
  24. Halla, N. et al. “Cosmetics preservation: A review on present strategies.” Molecules, vol. 23, no. 7, 2018, article 1571.
  25. Anurova, M.N. et al. “Modern preservatives of microbiological stability.” Pharmaceutical Chemistry Journal, vol. 53, no. 6, 2019, pp. 564–571.
  26. Seetaramaiah, K. et al. “Preservatives in food products: A review.” International Journal of Pharmaceutical and Biological Archives, vol. 2, no. 2, 2011, pp. 583–599.
  27. Kalpana, V.N. and V.D. Rajeswari. “Preservatives in beverages: Perception and needs.” Preservatives and Preservation Approaches in Beverages, Academic Press, 2019, pp. 1–30.
  28. Bensid, A. et al. “Antioxidant and antimicrobial preservatives: Properties, mechanism of action and applications in food.” Critical Reviews in Food Science and Nutrition, 2020, pp. 1–17.
  29. Kulkarni, C. et al. “Assessment of microbial contamination in commercial herbal oral medicinal liquids.” International Journal of Pharmaceutical Research and Development, vol. 2, no. 9, 2010, pp. 191–193.
  30. Noecker, R. “Effects of common ophthalmic preservatives on ocular health.” Advances in Therapy, vol. 18, no. 5, 2001, pp. 205–215.
  31. Yim, E. et al. “Contact dermatitis caused by preservatives.” Dermatitis, vol. 25, 2014, pp. 215–231.
  32. Reeder, M. and A.R. Atwater. “Parabens: The 2019 nonallergen of the year.” Cutis, vol. 103, no. 4, 2019, pp. 192–193.
  33. Abril, C. et al. “Uptake and translocation of multiresidue industrial and household contaminants in radish.” Chemosphere, vol. 268, 2021, article 128823.
  34. Guo, Y. and K. Kannan. “A survey of phthalates and parabens in personal care products from the United States.” Environmental Science and Technology, vol. 47, no. 24, 2013, pp. 14442–14449.
  35. Aubert, N. et al. “Systemic exposure to parabens: Pharmacokinetics and tissue distribution in rats.” Food and Chemical Toxicology, vol. 50, nos. 3–4, 2012, pp. 445–454.
  36. Moos, R.K. et al. “Parabens in 24-hour urine samples of the German Environmental Specimen Bank.” International Journal of Hygiene and Environmental Health, July 2015.
  37. Alvarez, M.A. et al. “Removal of parabens from water by UV-driven advanced oxidation processes.” Chemical Engineering Journal, vol. 379, 2020, article 122334.
  38. Cherian, P. et al. “Amended safety assessment of parabens as used in cosmetics.” International Journal of Toxicology, vol. 39, no. 1 suppl., 2020, pp. 5S–97S.
  39. Soni, M. et al. “Safety assessment of esters of p-hydroxybenzoic acid (parabens).” Food and Chemical Toxicology, vol. 43, no. 7, 2005, pp. 985–1015.
  40. Tade, R.S. et al. “Safety and toxicity assessment of parabens in pharmaceutical and food products.” Inventi Rapid: Pharmacy Practice, vol. 3, 2018, pp. 1–9.
  41. Ortega Morente, E. et al. “Biocide tolerance in bacteria.” International Journal of Food Microbiology, vol. 162, 2013, pp. 13–25.
  42. Williamson, D.A. et al. “Current and emerging topical antibacterials and antiseptics.” Clinical Microbiology Reviews, vol. 30, 2017, pp. 827–860.
  43. Membré, J.-M. and S. Dagnas. “Modeling microbial responses: Application to food spoilage.” Modeling in Food Microbiology, Elsevier, 2016, pp. 33–60.
  44. Alkafajy, S.A.Q. and R.A.A. Abdul-Jabbar. “Comprehensive effects of parabens in human physiology.” Annals of Tropical Medicine and Public Health, vol. 23, suppl. 20, 2020.
  45. Matwiejczuk, N. et al. “Protective effect of rosmarinic acid against methylparaben and propylparaben.” Nutrients, vol. 12, no. 5, 2020, article 1282.
  46. Dubey, D. et al. “Photosensitized methyl paraben induces apoptosis in human skin cells.” Food and Chemical Toxicology, vol. 108, 2017, pp. 171–185.
  47. Nassan, F.L. et al. “Personal care product use and urinary concentrations of parabens.” Environmental Health Perspectives, vol. 125, no. 8, 2017, article 087012.
  48. Nishihama, Y. et al. “Association between paraben exposure and menstrual cycle.” Reproductive Toxicology, vol. 63, 2016, pp. 107–113.
  49. Jiménez-Díaz, I. et al. “Menstrual blood concentrations of parabens and benzophenones.” Environmental Research, vol. 183, 2020, article 109228.
  50. Gálvez-Ontiveros, Y. et al. “Presence of parabens and bisphenols in food commonly consumed in Spain.” Foods, vol. 10, no. 1, 2021, article 92.
  51. Kim, J. and J. Chevrier. “Exposure to parabens and prevalence of obesity and metabolic syndrome.” Science of the Total Environment, vol. 713, 2020, article 135116.
  52. Nowak, K. et al. “Parabens and their effects on the endocrine system.” Molecular and Cellular Endocrinology, vol. 474, 2018, pp. 238–251.
  53. Bronowicka-Kłys, D.E. et al. “Role and impact of estrogens and xenoestrogens on cervical cancer.” Biomedicine and Pharmacotherapy, vol. 84, 2016, pp. 1945–1953.
  54. Berger, K. et al. “Associations of maternal exposure to triclosan and parabens.” Environmental Research, vol. 165, 2018, pp. 379–386.
  55. Aker, A.M. et al. “Repeated measures study of phenol and paraben biomarkers during gestation.” Environmental Health, vol. 18, 2019, article 28.
  56. Jurewicz, J. et al. “Environmental exposure to parabens and sperm chromosome disomy.” International Journal of Environmental Health Research, vol. 27, no. 5, 2017, pp. 332–343.
  57. Ahmed, Q.A. et al. “Effect of olive oil and hydroxytyrosol on sex hormones in male rats.” NVEO–Natural Volatiles and Essential Oils Journal, 2021, pp. 13072–13086.
  58. Ahmed, Q.A. et al. “The effect of olive oil and hydroxytyrosol on sex hormones and oxidative stress in male rats.” NVEO–Natural Volatiles and Essential Oils Journal, 2021, pp. 13072–13086.
  59. Šramkova, M. et al. “Parabens and their relationship to obesity.” Proceedings of the 21st European Congress of Endocrinology, vol. 63, BioScientifica, 2019.
  60. Quirós-Alcalá, L. et al. “Parabens and measures of adiposity among adults and children.” International Journal of Hygiene and Environmental Health, vol. 221, no. 4, 2018, pp. 652–660.
  61. Pollack, A.Z. et al. “Exposure to bisphenol A, chlorophenols, benzophenones, and parabens in relation to reproductive hormones in healthy women: A chemical mixture approach.” Environment International, vol. 120, 2018, pp. 137–144.
  62. Liu, W. et al. “Parabens exposure in early pregnancy and gestational diabetes mellitus.” Environment International, vol. 126, 2019, pp. 468–475.
  63. Kim, Y.R. et al. “Synergistic effects of octylphenol and isobutyl paraben on calbindin-D(9)K expression.” International Journal of Molecular Medicine, vol. 29, 2012, pp. 294–302.
  64. Halliwell, B. and J.M. Gutteridge. Free radicals in biology and medicine. Oxford University Press, 2015.
  65. Perez-Albaladejo, E. et al. “Comparative toxicity and endocrine disruption potential of plasticizers.” Toxicology in Vitro, vol. 38, 2017, pp. 41–48.
  66. Ahmed, Q.A. et al. “Effect of hydroxytyrosol and olive oil on hepcidin hormone.” Plant Archives, vol. 20, no. 2, 2020, pp. 1895–1902.
  67. Ahmed, Q. et al. “Effect of hydroxytyrosol and olive oil on oxidative stress in liver.” International Journal of Medical Sciences, vol. 5, no. 1, 2022, pp. 43–54.
  68. Ahmed, Q. et al. “Effect of hydroxytyrosol and olive oil on lipid profile and heart histology.” International Journal of Medical Sciences, vol. 5, no. 2, 2022, pp. 44–54.
  69. Yesilbursa, D. et al. “Lipid peroxides in obese patients and effects of weight loss.” International Journal of Obesity, vol. 29, no. 1, 2005, pp. 142–145.
  70. Alsudani, A.A. and H.A. Alhamadawi. “Physiological effects of food additives on the HPT axis.” Journal of Physics: Conference Series, vol. 1664, no. 1, 2020, article 012122.
  71. Smith, K.W. et al. “Urinary paraben concentrations and ovarian aging.” Environmental Health Perspectives, vol. 121, nos. 11–12, 2013, pp. 1299–1305.
  72. Vo, T.T. et al. “Potential estrogenic effects of parabens in female rats.” Reproductive Toxicology, vol. 29, no. 3, 2010, pp. 306–316.
  73. Wan, H.T. et al. “Targeting testis-specific proteins to inhibit spermatogenesis.” Expert Opinion on Therapeutic Targets, vol. 17, no. 7, 2013, pp. 839–855.
  74. Taylor, J.A. et al. “Estrogenic environmental chemicals and male urogenital development.” Journal of Steroid Biochemistry and Molecular Biology, vol. 127, nos. 1–2, 2011, pp. 83–95.
  75. Stukenborg, J.B. et al. “Endocrine disruptors and the male reproductive system.” Best Practice and Research: Clinical Endocrinology and Metabolism, vol. 35, no. 5, 2021, article 101567.
  76. Rahman, M.S. et al. “Gestational exposure to bisphenol A affects sperm function.” Environmental Health Perspectives, vol. 125, no. 2, 2017, pp. 238–245.
  77. Sharma, A. et al. “Endocrine-disrupting chemicals and male reproductive health.” Reproductive Medicine and Biology, vol. 19, no. 3, 2020, pp. 243–253.
  78. Fontenele, E. et al. “Testosterone and endocrine disruptors.” Testosterone, Springer, 2017, pp. 353–374.
  79. Boberg, J. et al. “Possible endocrine disrupting effects of parabens.” Reproductive Toxicology, vol. 30, 2010, pp. 301–312.
  80. Fransway, A.F. et al. “Paraben toxicology.” Dermatitis, vol. 30, 2019, pp. 32–45.
  81. Ara, C. et al. “Turmeric plays protective role against paraben-induced lesions.” Punjab University Journal of Zoology, vol. 35, no. 1, 2020, pp. 7–12.
  82. Cano, R. et al. “Endocrine-disrupting chemicals and fatty liver disease.” International Journal of Molecular Sciences, vol. 22, no. 9, 2021, article 4807.
  83. Cano-Sancho, G. et al. “Use and interpretation of blood biomarkers of endocrine disruptors.” Molecular and Cellular Endocrinology, vol. 499, 2020, article 110606.
  84. Szeląg, S. et al. “Propylparaben-induced disruption of energy metabolism.” Toxicology in Vitro, vol. 31, 2016, pp. 30–34.
  85. Adegoke, A.O. et al. “Effect of quercetin on liver oxidative stress induced by butylparaben.” International Journal of Medical and Health Sciences Research, vol. 8, no. 1, 2021, pp. 1–7.
  86. Özdemir, E. et al. “Antiandrogenic properties of propyl paraben.” Toxicology Research, vol. 7, no. 2, 2018, pp. 235–243.
  87. Kizhedath, A. et al. “Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro models.” Toxicology in Vitro, vol. 55, 2019, pp. 108–115.
  88. Kaur, K. et al. “Bisphenol A induces oxidative stress in lymphoblasts.” Free Radical Biology and Medicine, vol. 76, 2014, pp. 25–33.
  89. Selivanov, V.A. et al. “Reactive oxygen species production in mitochondria.” PLoS Computational Biology, vol. 7, 2011, article e1001115.
  90. Binukumar, B.K. et al. “Mitochondrial impairment following dichlorvos exposure.” Toxicology, vol. 270, 2010, pp. 77–84.
  91. Chen, S.C. et al. “Dioxin-induced mitochondrial dysfunction in trophoblast cells.” Molecular Human Reproduction, vol. 16, 2010, pp. 361–372.
  92. Khan, S. et al. “Bisphenol A-induced mitochondrial dysfunction.” Environmental Toxicology, vol. 31, no. 12, 2016, pp. 1922–1934.
  93. Priego, A.R. et al. “Bisphenol A modulates autophagy and kidney damage.” International Journal of Molecular Sciences, vol. 22, no. 13, 2021, article 7189.
  94. Arfaeinia, H. et al. “Urinary levels of unmetabolized parabens in women.” Environmental Research, vol. 200, 2021, article 111771.
  95. Zhang, Q. et al. “Sirtuin 3 deficiency aggravates kidney injury.” Journal of Translational Medicine, vol. 16, 2018, article 313.
  96. Perry, H.M. et al. “Dynamin-related protein 1 deficiency promotes AKI recovery.” Journal of the American Society of Nephrology, vol. 29, 2018, pp. 194–206.
  97. Peerapanyasut, W. et al. “N-acetylcysteine attenuates liver dysfunction after AKI.” Antioxidants, vol. 8, no. 10, 2019, article 497.
  98. Li, M. et al. “Prenatal exposure to propylparaben accelerates ovarian aging.” Environmental Pollution, vol. 285, 2021, article 117254.
  99. Kang, K.S. et al. “Decreased sperm number in offspring exposed to butylparaben.” Journal of Veterinary Medical Science, vol. 64, 2002, pp. 227–235.
  100. Jurewicz, J. et al. “Ovarian reserve parameters and urinary parabens.” Environmental Health, vol. 19, 2020, article 26.
  101. Lee, J.H. et al. “Parabens accelerate ovarian dysfunction.” International Journal of Environmental Research and Public Health, vol. 14, no. 2, 2017, article 161.
  102. Otasevic, V. et al. “Reactive oxygen, nitrogen and sulfur species in male fertility.” BioFactors, vol. 46, no. 2, 2020, pp. 206–219.
  103. Moeen, M.E.E. et al. “Oxidative stress alterations in rats treated with food additives.” International Journal of Advanced Research in Biological Sciences, vol. 5, no. 6, 2018, pp. 118–123.
  104. Santiago, J. et al. “Testicular signaling in sperm production.” Tissue-Specific Cell Signaling, Springer, 2020, pp. 225–255.
  105. Hubbard, T.D. et al. “Butylparaben multigenerational reproductive assessment.” Reproductive Toxicology, vol. 96, 2020, pp. 258–272.
  106. Sharma, R.P. et al. “Crosstalk mechanisms of endocrine disruptors.” Environment International, vol. 99, 2017, pp. 1–14.
  107. Wagner, H. et al. “Role of reactive oxygen species in male infertility.” Arab Journal of Urology, vol. 16, no. 1, 2018, pp. 35–43.
  108. Barati, E. et al. “Oxidative stress and male infertility.” Cellular and Molecular Life Sciences, vol. 77, no. 1, 2020, pp. 93–113.
  109. Darbandi, M. et al. “Reactive oxygen species and male reproductive hormones.” Reproductive Biology and Endocrinology, vol. 16, no. 1, 2018, article 87.
  110. Kovacik, A. et al. “Trace elements in semen and sperm quality.” Journal of Trace Elements in Medicine and Biology, vol. 50, 2018, pp. 399–407.
  111. Schreiber, E. et al. “Oxidative stress in testes exposed to n-butylparaben.” Food and Chemical Toxicology, vol. 131, 2019, article 110573.
  112. Smarr, M.M. et al. “Urinary antimicrobial biomarkers and semen quality.” Reproductive Toxicology, vol. 77, 2018, pp. 103–108.
  113. Samarasinghe, S.V.A.C. et al. “Parabens generate reactive oxygen species in human spermatozoa.” Andrology, vol. 6, no. 4, 2018, pp. 532–541.

Authors
Mohammed Kamel Ahmed, T., Mohammed Bakr, M., & Assi Ahmed, Q.
Venue
Scientific Research Journal of Pharmacy
Published
2022-10-27
Volume
02
Issue
02
Pages
1-11
ISSN
2788-9564 (ISSN-L)
OpenAlex
W7129077747
Cited by
3
References
0
Citations by year
2026: 2 · 2025: 1
FWCI
0.11
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
Scientific Research Journal of Pharmacy (publishedVersion, cc-by)
Topics
  • Physical Sciences › Chemistry › Analytical Chemistry › Dye analysis and toxicity
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural safety and regulations
Keywords
food preservatives, natural preservatives, antimicrobial agents, antioxidants, food spoilage prevention, endocrine disruption, oxidative stress, reproductive toxicity, environmental pollution, pharmaceutical preservatives

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