Cited by 8Posttraumatic Stress Disorder ResearchCOVID-19 and Mental HealthPsychotherapy Techniques and Applications

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Online narrative therapy intervention improves post-traumatic stress disorder symptoms, perceived stress, anxiety, and depression in nurses: a randomized controlled trial

Open access
Xue, Mengxin, Yu, Ping, Gu, Zhie, Sun, Yanfei·2025·Brazilian Journal of Psychiatry

Abstract

OBJECTIVE: To evaluate the effect of narrative therapy on post-traumatic stress disorder (PTSD) symptoms, perceived stress, anxiety, and depression in nurses. METHODS: A total of 92 clinical nurses with positive PTSD symptom screening results were randomly assigned (1:1) to the intervention or control group. The intervention group received narrative therapy and a psychological stress leaflet, while the control group received only a psychological stress leaflet. PTSD, perceived stress, anxiety, and depression were measured before and after the intervention to assess the effect of narrative therapy. RESULTS: After the intervention, the intervention group showed significantly lower PTSD symptom levels (p = 0.025), perceived stress (p = 0.033), anxiety (p = 0.004), and depression (p = 0.015) than the control group. Regarding the dichotomous PTSD, anxiety, and depression outcomes, there was a statistically significant decrease in the number of positive cases of PTSD (p = 0.030) and anxiety (p = 0.002), but no significant change in the number of positive cases of depression (p = 0.060). CONCLUSION: Narrative therapy is expected to alleviate PTSD symptoms, stress, anxiety, and depression among frontline clinical nurses, and healthcare managers should consider narrative therapy interventions to improve the mental health of their nursing staff. CLINICAL TRIAL REGISTRATION: ChiCTR2200058472. Registration date: April 09, 2022. Date of first recruitment: June 1, 2022.

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TL;DR

In a two-hospital cluster-randomized trial of 92 clinical nurses with positive PTSD screening, an 8-week online narrative therapy program plus a stress leaflet improved PTSD symptoms, perceived stress, anxiety, and depression compared with leaflet only. Positive cases decreased significantly for PTSD and anxiety but not depression.

Key findings

  • After the intervention, the intervention group had significantly lower PTSD symptom levels (p = 0.025), perceived stress (p = 0.033), anxiety (p = 0.004), and depression (p = 0.015) than the control group.
  • For PTSD symptom clusters, criteria B, D, and E scores were significantly lower in the intervention group than the control group (p < 0.05), while criterion C (avoidance) did not differ significantly (p > 0.05).
  • The number of positive PTSD cases (p = 0.030) and anxiety cases (p = 0.002) decreased significantly in the intervention group versus control, but there was no significant change in positive depression cases (p = 0.060).
  • Baseline demographic characteristics and PTSD, perceived stress, anxiety, and depression scores did not differ significantly between groups (p > 0.05).

Methods

  • Cluster randomized controlled trial conducted in two tertiary hospitals in Jiangsu Province from June 2022 to August 2022. A total of 92 registered nurses aged ≥ 18 years with a PTSD checklist score ≥ 33 were randomized 1:1 to intervention (n = 46) or control (n = 46); the target sample size was 88 based on G*Power.
  • The intervention group received a psychological stress leaflet plus one-to-one online narrative therapy video calls of 45-60 minutes once weekly for 8 weeks; the control group received only the psychological stress leaflet. Outcomes were measured with the PTSD Checklist for DSM-5, Perceived Stress Scale, Generalized Anxiety Disorder Scale, and Patient Health Questionnaire-9 before and after the intervention.
  • Intention-to-treat analysis was used for missing data. Categorical variables were analyzed with Pearson’s chi-square test; continuous variables used independent sample t-tests or Mann-Whitney U tests. SPSS 26.0 was used, with p < 0.05 considered statistically significant (two-tailed). Two intervention participants discontinued and four control participants did not complete the final assessment.

Limitations

  • The paper states: PTSD symptoms were assessed with the self-reported PTSD Checklist for DSM-5 rather than a structured clinical interview; the sample was 96.7% women; the study used a quantitative design only; time elapsed since the traumatic experience was not determined; and long-term effects were not assessed.
  • Evident from the text: the sample was small (92 nurses) and drawn from only two tertiary hospitals, with cluster randomization by institution, which may limit generalizability and introduce cluster-level confounding.
  • Evident from the text: the methods do not describe blinding of participants, interventionists, or outcome assessors, and the control condition was a leaflet only rather than an active comparator.

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Integrity signals

Registry

Crossref · 10.47626/1516-4446-2024-3740

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Figures

Figure 1 Flowchart of participant inclusion according to The Consolidated Standards of Reporting Trials protocol.
Figure 1 Flowchart of participant inclusion according to The Consolidated Standards of Reporting Trials protocol.CC BY-NC · PubMed Central
Figure 2 Comparison of PTSD scores, and scores for criteria B, C, D, and E between groups after the intervention. PTSD = post-traumatic stress disorder.
Figure 2 Comparison of PTSD scores, and scores for criteria B, C, D, and E between groups after the intervention. PTSD = post-traumatic stress disorder.CC BY-NC · PubMed Central

Verification

Claims the paper makes

9 Own result · 8 Not checked yet · 5 Own method · 4 Own interpretation · 1 Sources not found

Verify all 13 references — free account

Show all 18 claims

  • It may state two separate claims as one. 6
  • Probably not a substantial claim. 4
9 of 9
  • The paper relies on this without support.

    The psychological stress leaflet given to both groups does not itself substantially reduce PTSD symptoms, perceived stress, anxiety, or depression.

    “The intervention group received narrative therapy and a psychological stress leaflet, while the control group received only a psychological stress leaflet.”
    “Two groups of nurses received psychological stress leaflets, on the basis of which the intervention group underwent a one-to-one online NT intervention program, while the control group did not.”
  • The paper relies on this without support.

    The 92 nurses from two tertiary hospitals in Jiangsu Province are representative of frontline clinical nurses in general.

    “Ultimately, we recruited 92 registered nurses from two hospitals (intervention group = 46, control group = 46).”
    “Narrative therapy is expected to alleviate PTSD symptoms, stress, anxiety, and depression among frontline clinical nurses, and healthcare managers should consider narrative therapy interventions to improve the mental health of their nursing staff.”
  • The paper relies on this without support.

    The observed benefits are attributable to the specific narrative therapy techniques rather than to nonspecific factors such as additional attention or therapeutic contact.

    “The intervention group received narrative therapy and a psychological stress leaflet, while the control group received only a psychological stress leaflet.”
    “After 8 weeks of intervention, with the exception of criterion C, the intervention group showed lower criteria B, D, and E PTSD symptoms than the control group.”
3 of 3

Citations

Cites

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Metadata

Authors
Xue, M., Yu, P., Gu, Z., & Sun, Y.
Affiliations
  • Nanjing General Hospital of Nanjing Military Command (CN)
  • Northern Jiangsu People's Hospital (CN)
Venue
Brazilian Journal of Psychiatry
Published
2025
Volume
47
Pages
e20243740-e20243740
ISSN
  • 1516-4446 (ISSN-L)
  • 1809-452X
OpenAlex
W4402901222
Cited by
8
References
1
Citations by year
2026: 5 · 2025: 3
FWCI
2.88
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Brazilian Journal of Psychiatry (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • PubMed Central (publishedVersion, cc-by-nc)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Nanjing University
Topics
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords
narrative therapy, post-traumatic stress disorder, nurses, perceived stress, anxiety, depression, online intervention, workplace mental health
MeSH terms
Adult, Anxiety, Depression, Female, Humans, Male, Middle Aged, Nurses, Stress Disorders, Post-Traumatic, Stress, Psychological, Treatment Outcome, Young Adult, Narrative Therapy

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