The DOI matches its Crossref record.
Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate).
Open accessAbstract
Permanent parkinsonism was observed in a man with chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). Symptoms developed at 37 years of age, two years after exposure had ceased. To our knowledge, this is the second report on parkinsonism associated with exposure to maneb. Manganese is a well-known parkinsonigen toxin in humans. More recently, it has been shown that dithiocarbamates can also induce extrapyramidal syndromes. The biochemical effects of manganese and dithiocarbamates are reviewed and their possible neurotoxic mechanisms are discussed. Both of these components may have played a role in this case.
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Cited by
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Wirdefeldt, K., Adami, H.-O., Cole, P., Trichopoulos, D., & Mandel, J. (2011) · European Journal of Epidemiology · doi:10.1007/s10654-011-9581-6 · Cited by 1,199
Potential developmental neurotoxicity of pesticides used in Europe
Bjørling-Poulsen, M., Andersen, H. R., & Grandjean, P. (2008) · Environmental Health · doi:10.1186/1476-069x-7-50 · Cited by 407
Mokgobu, M. I., Cholo, M. C., Anderson, R., Steel, H. C., Motheo, M. P., Hlatshwayo, T. N., Tintinger, G. R., & Theron, A. J. (2015) · Journal of Immunotoxicology · doi:10.3109/1547691x.2014.902877 · Cited by 30
Metadata
- Authors
- Meco, G., Bonifati, V, Vanacore, N., & Fabrizio, E.
- Venue
- Scandinavian Journal of Work, Environment & Health
- Published
- 1994-08
- Volume
- 20
- Issue
- 4
- Pages
- 301-305
- ISSN
- 0355-3140 (ISSN-L)
- 1795-990X
- OpenAlex
- W2075943484
- Cited by
- 200
- References
- 0
- FWCI
- 1.96
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). https://app.cochat.ai/papers/10.5271/sjweh.1394
- The paper
- Meco, G., Bonifati, V, Vanacore, N., & Fabrizio, E. (1994). Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). Scandinavian Journal of Work, Environment & Health. https://doi.org/10.5271/sjweh.1394
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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