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Cited by 357

The DOI matches its Crossref record; 116 of the 116 references it cites were found in a registry or an index.

Targeted therapies in breast cancer: New challenges to fight against resistance

Open access
Masoud, Viviana, Pagès, Gilles·2017·World Journal of Clinical Oncology

Abstract

Breast cancer is the most common type of cancer found in women and today represents a significant challenge to public health. With the latest breakthroughs in molecular biology and immunotherapy, very specific targeted therapies have been tailored to the specific pathophysiology of different types of breast cancers. These recent developments have contributed to a more efficient and specific treatment protocol in breast cancer patients. However, the main challenge to be further investigated still remains the emergence of therapeutic resistance mechanisms, which develop soon after the onset of therapy and need urgent attention and further elucidation. What are the recent emerging molecular resistance mechanisms in breast cancer targeted therapy and what are the best strategies to apply in order to circumvent this important obstacle? The main scope of this review is to provide a thorough update of recent developments in the field and discuss future prospects for preventing resistance mechanisms in the quest to increase overall survival of patients suffering from the disease.

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Crossref · 10.5306/wjco.v8.i2.120

Cites

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Citations

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Metadata

Authors
Masoud, V., & Pagès, G.
Venue
World Journal of Clinical Oncology
Published
2017
Volume
8
Issue
2
Pages
120
ISSN
2218-4333 (ISSN-L)
OpenAlex
W2604622211
Cited by
357
References
116
FWCI
19.44
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Targeted therapies in breast cancer: New challenges to fight against resistance. https://app.cochat.ai/papers/10.5306/wjco.v8.i2.120
The paper
Masoud, V., & Pagès, G. (2017). Targeted therapies in breast cancer: New challenges to fight against resistance. World Journal of Clinical Oncology. https://doi.org/10.5306/wjco.v8.i2.120

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.