The DOI matches its Crossref record.
Focused Ultrasound for Essential Tremor: Review of the Evidence and Discussion of Current Hurdles
Open accessAbstract
Background: While there is no breakthrough progress in the medical treatment of essential tremor (ET), in the past decades several remarkable achievements happened in the surgical field, such as radiofrequency thalamotomy, thalamic deep brain stimulation, and gamma knife thalamotomy. The most recent advance in this area is magnetic resonance-guided focused ultrasound (MRgFUS). Methods: The purpose of this review is to discuss the new developments and trials of MRgFUS in the treatment of ET and other tremor disorders. Results: MRgFUS is an incisionless surgery performed without anesthesia and ionizing radiation (no risk of cumulative dose and delayed side effects). Studies have shown the safety and effectiveness of unilateral MRgFUS-thalamotomy in the treatment of ET. It has been successfully used in a few patients with Parkinson’s disease-related tremor, and in fewer patients with fragile X-associated tremor/ataxia syndrome. The safety and long-term effects of the procedure are still unclear, as temporary and permanent adverse events have been reported as well as recurrence of tremor. Discussion: MRgFUS is a promising new surgical approach with a number of unknowns and unsolved issues. It represents a valuable option particularly for patients who refused or could not be candidates for other procedures, deep brain stimulation in particular.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In summary, surgery, DBS, and focused ultrasound are effective second-line treatments (50–52).”
From A Review on Wearable Technologies for Tremor Suppression (2021) · cites this paper as [52]
Citations
Cites
Still being checked.
Cited by
Sorted by citations
Tremor habituation to deep brain stimulation: Underlying mechanisms and solutions
Fasano, A. A., & Helmich, R. C. G. (2019) · Movement Disorders · doi:10.1002/mds.27821 · Cited by 112
Self-citationFocused Ultrasound for Immunomodulation of the Tumor Microenvironment
Joiner, J. B., Pylayeva‐Gupta, Y., & Dayton, P. A. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.1901430 · Cited by 90
Giordano, M., Caccavella, V. M., Zaed, I., Manzillo, L. F., Montano, N., Olivi, A., & Polli, F. M. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-323216 · Cited by 87
A Review on Wearable Technologies for Tremor Suppression
Lora-Millan, J. S., Delgado-Oleas, G., Benito-León, J., & Rocon, E. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.700600 · Cited by 62
Kapadia, A., Elias, G., Boutet, A., Germann, J., Pancholi, A., Chu, P. P. W., Zhong, J., Fasano, A., Munhoz, R., Chow, C., et al. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-322745 · Cited by 53
Self-citation
Metadata
- Authors
- Rohani, M., & Fasano, A.
- Affiliations
- Iran University of Medical Sciences (IR)
- University of Toronto (CA)
- Corresponding author
- Fasano, Alfonso
- Venue
- Tremor and Other Hyperkinetic Movements
- Publisher
- Ubiquity Press, Ltd.
- Published
- 2017-05-05
- Volume
- 7
- Issue
- 0
- Pages
- 462
- ISSN
- 2160-8288 (ISSN-L)
- OpenAlex
- W4232352638
- Cited by
- 73
- References
- 0
- Citations by year
- 2026: 5 · 2025: 16 · 2024: 10 · 2023: 5 · 2022: 8 · 2021: 5 · 2020: 9 · 2019: 8 · 2018: 7
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc-nd
- creativecommons.org/licenses/by/4.0 (vor)
- Locations
- Tremor and Other Hyperkinetic Movements (publishedVersion, cc-by-nc-nd)
- Columbia Academic Commons (Columbia University)
- Funders
- Michael J. Fox Foundation for Parkinson's Research
- University of Toronto
- Topics
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Physical Sciences › Engineering › Biomedical Engineering › Ultrasound and Hyperthermia Applications
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Keywords
- essential tremor, MR-guided focused ultrasound, MRgFUS thalamotomy, tremor disorders, fragile X-associated tremor/ataxia syndrome, deep brain stimulation, adverse events
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Focused Ultrasound for Essential Tremor: Review of the Evidence and Discussion of Current Hurdles. https://app.cochat.ai/papers/10.5334/tohm.378
- The paper
- Rohani, M., & Fasano, A. (2017). Focused Ultrasound for Essential Tremor: Review of the Evidence and Discussion of Current Hurdles. Tremor and Other Hyperkinetic Movements. https://doi.org/10.5334/tohm.378
