Effects of age of diagnosis and dietary compliance on growth parameters of patients with celiac disease
Open accessAbstract
INTRODUCTION: The objective of this study was to evaluate the relation between age at diagnosis and compliance to gluten free diet (GFD) on growth in children with celiac disease and the factors that influenced compliance to GFD. POPULATION AND METHODS: Celiac disease (CD) patients with villous atrophy followed in our hospital between January 2015 and January 2017, were included. They were classified according to diagnosis age and GFD compliance. Patients' anthropometric characteristics at diagnosis and follow-up were compared. RESULTS: There were 73 patients with 10.4 ± 4.5 years of average age, 35 (47.9%) patients had a short stature at diagnosis, the ages of patients who had short stature (7.8 ± 4.2 years) were higher than those who did not (5.1 ± 4.3 years) (p= 0.005). At diagnosis, 33 (45.2%) patients were aged ≤6 years, 40 (54.8%) were aged >6 years. The height and weight z-scores of patients who were diagnosed at >6 years of age were significantly lower than those who were diagnosed ≤6 years of age both at diagnosis (p= 0.01 and 0.04) and at last control (p= 0.001 and 0.001), respectively. Forty-five (61.6%) patients were fully compliant with GFD. In comparison of anthropometric data in terms of GFD compliance, the increase in BMI and weight z-score in the fully compliant group was found to be significantly higher when compared with the other group. CONCLUSIONS: Delay in CD diagnosis negatively affected both the height and weight and other growth parameters. GFD compliance positively affected the patients' all growth parameters, especially weight and BMI z-score.
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Negative TGA is associated with rapid weight recovery but does not seem to have the same long-term effect on catch-up of height.
“Negative TGA is associated with a rapid weight recovery but does not seem to have the same long-term effect on catch-up of height (29, 59, 60).”
From ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease. (2022) · cites this paper as [59]
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Effect of gluten-free diet on the growth and nutritional status of children with coeliac disease
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ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease.
Mearin, M. L., Agardh, D., Antunes, H., Al‐toma, A., Auricchio, R., Castillejo, G., Catassi, C., Ciacci, C., Discepolo, V., Dolinsek, J., et al. (2022) · Journal of pediatric gastroenterology and nutrition · doi:10.1097/mpg.0000000000003540 · Cited by 186 · see citing works
- Authors
- Comba, A., Çaltepe, G., Yüce, Ö., Erena, E., & Kalaycı, A. G.
- Affiliations
- Ondokuz Mayıs University (TR)
- Venue
- Archivos Argentinos de Pediatria
- Publisher
- Sociedad Argentina de Pediatria
- Published
- 2018-08-01
- Volume
- 116
- Issue
- 4
- Pages
- 248-255
- ISSN
- 0325-0075 (ISSN-L)
- OpenAlex
- W2980294434
- Cited by
- 19
- References
- 1
- Citations by year
- 2025: 1 · 2024: 3 · 2023: 5 · 2022: 2 · 2021: 1 · 2020: 5 · 2019: 2
- FWCI
- 1.93
- Type
- journal article
- Language
- es
- Open access
- diamond
- doi.org
- Locations
- Archivos Argentinos de Pediatria (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Medicine › Surgery › Eosinophilic Esophagitis
- Keywords
- celiac disease, age at diagnosis, gluten-free diet compliance, growth parameters, short stature, height z-score, weight z-score, body mass index, pediatric celiac disease, villous atrophy
- MeSH terms
- Adolescent, Age Factors, Anthropometry, Body Height, Body Weight, Celiac Disease, Child, Child, Preschool, Female, Follow-Up Studies, Humans, Infant, Male, Patient Compliance, Body Mass Index, Diet, Gluten-Free, Delayed Diagnosis
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