The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Caffeine-induced cardiac arrhythmia: an unrecognised danger of healthfood products
Abstract
We describe a 25-year-old woman with pre-existing mitral valve prolapse who developed intractable ventricular fibrillation after consuming a "natural energy" guarana health drink containing a high concentration of caffeine. This case highlights the need for adequate labelling and regulation of such products.
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“In general, acute intake of caffeine stimulates a modest increase in blood pressure (both systolic and diastolic), effects on heart rate (bradycardia or tachycardia, depending on dose), and neuroendocrine effects (release of epinephrine, norepinephrine, and renin) (101).”
From The Safety of Ingested Caffeine: A Comprehensive Review (2017) · cites this paper as [101]
Citations
Cites
Goodman & Gilman's The Pharmacological Basis of Therapeutics
Brunton, L. L. (1985) · Cited by 7,321
Prevalence and Clinical Outcome of Mitral-Valve Prolapse
Freed, L. A., Levy, D. A., Levine, R. A., Larson, M. G., Evans, J. C., Fuller, D. L., Lehman, B. T., & Benjamin, E. J. (1999) · New England Journal of Medicine · doi:10.1056/nejm199907013410101 · Cited by 1,174
Alternative Medicine — The Risks of Untested and Unregulated Remedies
Angell, M. E., & Kassirer, J. P. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809173391210 · Cited by 689
Harmless Herbs? A Review of the Recent Literature
Ernst, E. (1998) · The American Journal of Medicine · doi:10.1016/s0002-9343(97)00397-5 · Cited by 632
CRC Handbook of Medicinal Herbs
Duke, J. A. (1990) · International Clinical Psychopharmacology · doi:10.1097/00004850-199001000-00014 · Cited by 504
Goldfrank's Toxicologic Emergencies.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-821_6 · Cited by 478
Long-term follow-up of idiopathic mitral valve prolapse in 300 patients: A prospective study
Düren, D. R., Becker, A. E., & Dunning, A. J. (1988) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(88)90164-7 · Cited by 272
Toxicity of Over-the-Counter Stimulants
Pentel, P. R. (1984) · JAMA · doi:10.1001/jama.1984.03350140044023 · Cited by 183
Kessler, D. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200006083422309 · Cited by 104
Five Cases of Fatal Overdose from Caffeine-Containing "Look-Alike" Drugs
Garriott, J. C., Simmons, L. M., Poklis, A., & Mackell, M. A. (1985) · Journal of Analytical Toxicology · doi:10.1093/jat/9.3.141 · Cited by 79
Cited by
Sorted by citations
Health effects of energy drinks on children, adolescents, and young adults
Seifert, S. M., Schaechter, J. L., Hershorin, E. R., & Lipshultz, S. E. (2011) · Pediatrics · doi:10.1542/peds.2009-3592 · Cited by 893
The Safety of Ingested Caffeine: A Comprehensive Review
Temple, J. L., Bernard, C., Lipshultz, S. E., Czachor, J. D., Westphal, J. A., & Mestre, M. A. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00080 · Cited by 557
Safety issues associated with commercially available energy drinks
Clauson, K. A., Shields, K. M., McQueen, C. E., & Persad, N. (2008) · Journal of the American Pharmacists Association · doi:10.1331/japha.2008.07055 · Cited by 300
Energy drinks: health risks and toxicity
Gunja, N., & Brown, J. A. (2012) · The Medical Journal of Australia · doi:10.5694/mja11.10838 · Cited by 240
Cardiac arrest in a young man following excess consumption of caffeinated “energy drinks”
Berger, A., & Alford, K. (2009) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2009.tb02263.x · Cited by 222
Metadata
- Authors
- Cannon, M. E., Cooke, C. T., & McCarthy, J. S.
- Affiliations
- Fremantle Hospital (AU)
- Queen Elizabeth II Medical Centre (AU)
- The University of Western Australia (AU)
- ORCID
- McCarthy, James S
- Venue
- Medical Journal of Australia
- Publisher
- AMPCo
- Published
- 2001-05
- Volume
- 174
- Issue
- 10
- Pages
- 520-521
- ISSN
- 0025-729X (ISSN-L)
- 1326-5377
- OpenAlex
- W56477952
- Cited by
- 136
- References
- 17
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 6 · 2020: 6 · 2019: 4 · 2018: 7 · 2017: 13 · 2016: 4 · 2015: 7 · 2014: 7 · 2013: 10 · 2012: 15
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- The Medical Journal of Australia (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Keywords
- caffeine, cardiac arrhythmias, ventricular fibrillation, guarana, health foods, functional beverages, mitral valve prolapse, product labeling, food regulation, adverse drug reactions
- MeSH terms
- Adult, Beverages, Caffeine, Drug Combinations, Female, Humans, Mitral Valve Prolapse, Theobromine, Theophylline, Ventricular Fibrillation, Fatal Outcome, Food, Organic
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