Adrenal crises in children treated with high-dose inhaled corticosteroids for asthma
Abstract
Three children presented with adrenal crises, manifested by vomiting and hypoglycaemia, after protracted courses of high-dose inhaled corticosteroids for asthma. Significant dose reduction was possible in all three without loss of asthma control, emphasising the importance of back-titration to minimise dose. Parents of children taking high doses of inhaled corticosteroids should be alerted to the clinical features of adrenal insufficiency. If suspected, prompt medical assessment should be arranged, including serum glucose and cortisol measurement.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In a case series, 3 children with asthma on high dose inhaled corticosteroids were found to have secondary adrenal insufficiency after presenting with hypoglycaemia, accompanied by vomiting, drowsiness and tiredness.
“In a case series, 3 children with a background of asthma who were on a high dose of inhaled corticosteroids, were found to have SAI after presenting with hypoglycaemia, accompanied by vomiting, drowsiness and tiredness.”
From Hypoglycaemia in adrenal insufficiency (2023) · cites this paper as [30]
The citation lists haven’t been fetched yet
References 19 · Cited by 54
- Authors
- Macdessi, J. S., Asperen, P. P., Randell, T. L., Donaghue, K. C., Ambler, G. R., & Mellis, C. M.
- Affiliations
- Children's Hospital at Westmead (AU)
- The University of Sydney (AU)
- Venue
- Medical Journal of Australia
- Publisher
- AMPCo
- Published
- 2003-03
- Volume
- 178
- Issue
- 5
- Pages
- 214-216
- ISSN
- 0025-729X (ISSN-L)
- 1326-5377
- OpenAlex
- W20194251
- Cited by
- 54
- References
- 19
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2019: 2 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 5 · 2013: 2 · 2012: 1
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- The Medical Journal of Australia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Keywords
- adrenal crisis, adrenal insufficiency, inhaled corticosteroids, asthma, children, hypoglycemia, vomiting, dose reduction, back titration, asthma control
- MeSH terms
- Adrenal Cortex Hormones, Adrenal Insufficiency, Asthma, Child, Child, Preschool, Humans, Hydrocortisone, Hypoglycemia, Male, Vomiting
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
