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Cited by 115Ovarian function and disordersClinical practice guidelines implementationReproductive Health and Technologies

The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.

Translation and implementation of the Australian‐led PCOS guideline: clinical summary and translation resources from the International Evidence‐based Guideline for the Assessment and Management of Polycystic Ovary Syndrome

Open access
Teede, Helena J, Misso, Marie L, Boyle, Jacqueline A, Garad, Rhonda M, McAllister, Veryan, Downes, Linda, Gibson‐Helm, Melanie, Hart, Roger J, Rombauts, Luk, Moran, Lisa, Dokras, Anuja, Laven, Joop, Piltonen, Terhi, Rodgers, Raymond J, Thondan, Mala, Costello, Michael F, Norman, Robert J, the International PCOS Network, Baye, Estifanos, Brennan, Leah, Harrison, Cheryce, Hutchison, Samantha, Joham, Anju, Johnson, Louise, Jordan, Cailin, Kulkarni, Jayashri, Mansfield, Darren, Marsh, Kate, Mol, Ben W, Peña, Alexia, Rodgers, Raymond, Speight, Jane, Stepto, Nigel, Tassone, Eliza C, Wan, Angela, Woolcock, Jane·2018·Medical Journal of Australia
DOI 10.5694/mja18.00656
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Abstract

INTRODUCTION: We have developed the first international evidence-based guideline for the diagnosis and management of polycystic ovary syndrome (PCOS), with an integrated translation program incorporating resources for health professionals and consumers. The development process involved an extensive Australian-led international and multidisciplinary collaboration of health professionals and consumers over 2 years. The guideline is approved by the National Health and Medical Research Council and aims to support both health professionals and women with PCOS in improving care, health outcomes and quality of life. A robust evaluation process will enable practice benchmarking and feedback to further inform evidence-based practice. We propose that this methodology could be used in developing and implementing guidelines for other women's health conditions and beyond. Main recommendations: The recommendations cover the following broad areas: diagnosis, screening and risk assessment depending on life stage; emotional wellbeing; healthy lifestyle; pharmacological treatment for non-fertility indications; and assessment and treatment of infertility. Changes in management as a result of this guideline: •Diagnosis:▪when the combination of hyperandrogenism and ovulatory dysfunction is present, ultrasound examination of the ovaries is not necessary for diagnosis of PCOS in adult women;▪requires the combination of hyperandrogenism and ovulatory dysfunction in young women within 8 years of menarche, with ultrasound examination of the ovaries not recommended, owing to the overlap with normal ovarian physiology; and▪adolescents with some clinical features of PCOS, but without a clear diagnosis, should be regarded as "at risk" and receive follow-up assessment.•Screening for metabolic complications has been refined and incorporates both PCOS status and additional metabolic risk factors.•Treatment of infertility: letrozole is now first line treatment for infertility as it improves live birth rates while reducing multiple pregnancies compared with clomiphene citrate.

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Research works printed but not linked: 3

  1. TeedeH LegroR NormanR.A vision for change in PCOS through international collaboration.Semin Reprod Med2018; in press.
  2. National Institutes of Health.NIH evidence‐based methodology workshop on Polycystic Ovary Syndrome: executive summary. 3‐5 Dec2012.https://prevention‐archive.od.nih.gov/docs/programs/pcos/FinalReport.pdf(viewed Aug 2018).
  3. Australian Bureau of Statistics, 2006, 4715.0 National Aboriginal and Torres Strait Islander Health Survey, 2004‐05

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Metadata

Authors
Teede, H. J., Misso, M. L., Boyle, J. A., Garad, R. M., McAllister, V., Downes, L., Gibson‐Helm, M., Hart, R. J., Rombauts, L., Moran, L., Dokras, A., Laven, J., Piltonen, T., Rodgers, R. J., Thondan, M., Costello, M. F., Norman, R. J., the International PCOS Network, Baye, E., Brennan, L., Harrison, C., Hutchison, S., Joham, A., Johnson, L., Jordan, C., Kulkarni, J., Mansfield, D., Marsh, K., Mol, B. W., Peña, A., Rodgers, R., Speight, J., Stepto, N., Tassone, E. C., Wan, A., & Woolcock, J.
Affiliations
  • Monash Health (AU)
  • National Health and Medical Research Council (AU)
  • The University of Western Australia (AU)
  • Monash University (AU)
  • University of Pennsylvania (US)
  • Erasmus MC (NL)
  • Oulu University Hospital (FI)
  • National Health and Medical Research Council Centre for Research Excellence in PCOS, Monash and Adelaide Universities, Melbourne, VIC
  • Harp Family Medical Centre, Melbourne, VIC
  • UNSW Sydney (AU)
Corresponding author
Teede, Helena J
ORCID
Venue
Medical Journal of Australia
Publisher
Wiley
Published
2018-10
Volume
209
Issue
S7
Pages
S3-S8
ISSN
  • 0025-729X (ISSN-L)
  • 1326-5377
DOI
10.5694/mja18.00656
OpenAlex
W2893517293
Cited by
115
References
27
Citations by year
2026: 2 · 2025: 9 · 2024: 10 · 2023: 18 · 2022: 16 · 2021: 20 · 2020: 24 · 2019: 11 · 2018: 3
FWCI
15.55
Type
journal article
Language
en
Open access
Licence
Locations
  • The Medical Journal of Australia (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
  • UWA Profiles and Research Repository (UWA) (submittedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
Keywords
polycystic ovary syndrome, guideline translation, patient information resources, hyperandrogenism, ovulatory dysfunction, PCOS diagnosis, PCOS screening, metabolic risk assessment, infertility treatment, letrozole, clomiphene citrate, adolescents, women's health
MeSH terms
Letrozole, Adolescent, Adult, Clomiphene, Female, Humans, Infertility, Female, Polycystic Ovary Syndrome, Pregnancy, Reproductive Medicine, Evidence-Based Medicine, Disease Management, Internationality, Young Adult

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