The carbon footprint of pathology testing
Open accessAbstract
Objectives To estimate the carbon footprint of five common hospital pathology tests: full blood examination; urea and electrolyte levels; coagulation profile; C-reactive protein concentration; and arterial blood gases. Design, setting Prospective life cycle assessment of five pathology tests in two university-affiliated health services in Melbourne. We included all consumables and associated waste for venepuncture and laboratory analyses, and electricity and water use for laboratory analyses. Main outcome measure Greenhouse gas footprint, measured in carbon dioxide equivalent (CO2e) emissions. Results CO2e emissions for haematology tests were 82 g/test (95% CI, 73–91 g/test) for coagulation profile and 116 g/test (95% CI, 101–135 g/test) for full blood examination. CO2e emissions for biochemical tests were 0.5 g/test CO2e (95% CI, 0.4–0.6 g/test) for C-reactive protein (low because typically ordered with urea and electrolyte assessment), 49 g/test (95% CI, 45–53 g/test) for arterial blood gas assessment, and 99 g/test (95% CI, 84–113 g/test) for urea and electrolyte assessment. Most CO2e emissions were associated with sample collection (range, 60% for full blood examination to 95% for coagulation profile); emissions attributable to laboratory reagents and power use were much smaller. Conclusion The carbon footprint of common pathology tests was dominated by those of sample collection and phlebotomy. Although the carbon footprints were small, millions of tests are performed each year in Australia, and reducing unnecessary testing will be the most effective approach to reducing the carbon footprint of pathology. Together with the detrimental health and economic effects of unnecessary testing, our environmental findings should further motivate clinicians to test wisely.
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The carbon emissions of one complete STR profile are comparable to those generated by a full blood examination in a hospital setting.
“However, a rough theoretical LCA suggests that one complete STR profile contributes roughly 0.1 kg carbon dioxide equivalent (CO2e) (Table 4), comparable to the carbon emissions generated by a full blood examination in a hospital setting [150].”
From Genetic Insights into the Economic Toll of Cell Line Misidentification: A Comprehensive Review (2026) · cites this paper as [150]
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Genetic Insights into the Economic Toll of Cell Line Misidentification: A Comprehensive Review
Weiskirchen, R. (2026) · Medical Sciences · doi:10.3390/medsci14010025 · Cited by 4 · see citing works
- Authors
- McAlister, S., Barratt, A. L., Bell, K. J., & McGain, F.
- Affiliations
- The University of Melbourne (AU)
- The University of Sydney (AU)
- Corresponding author
- McAlister, Scott
- Venue
- Medical Journal of Australia
- Publisher
- Wiley
- Published
- 2020-04-18
- Volume
- 212
- Issue
- 8
- Pages
- 377-382
- ISSN
- 0025-729X (ISSN-L)
- 1326-5377
- OpenAlex
- W3016965265
- Cited by
- 198
- References
- 1
- Citations by year
- 2026: 36 · 2025: 48 · 2024: 41 · 2023: 24 · 2022: 20 · 2021: 20 · 2020: 9
- FWCI
- 6.55
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- The Medical Journal of Australia (publishedVersion)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- The Sydney eScholarship Repository (The University of Sydney) (submittedVersion)
- Funders
- Department of Health, State Government of Victoria
- National Health and Medical Research Council (1104136)
- Topics
- Physical Sciences › Environmental Science › Environmental Engineering › Environmental Impact and Sustainability
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Health Sciences › Health Professions › General Health Professions › Healthcare cost, quality, practices
- Keywords
- carbon footprint, greenhouse gas emissions, life cycle assessment, venipuncture, phlebotomy, sample collection, coagulation parameters, C-reactive protein, arterial blood gases, laboratory reagents, power consumption, water consumption, unnecessary testing, environmental impact of healthcare
- MeSH terms
- Australia, Humans, Pathology, Specimen Handling, Phlebotomy, Carbon Footprint
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